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111 Cards in this Set
- Front
- Back
In the newborn exam, what are 4 things that you should ask in the History?
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- Genetic history (mother + father)
- Prior pregnancies and outcomes - Antipartum/Intrapartum events (prenatal care, substance use, maternal illness/medications, infections like GBS HBV and HSV, preterm labor, intact vs. ruptured membranes, blood type) - Delivery: Vaginal or Caesarian Section |
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What is better, a low or high APGAR score?
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High
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-What is considered full term in weeks for a newborn?
-What is considered pre-term? -What is considered post-term? |
Term = 37-42 weeks
Preterm = < 37 weeks Post-term = > 42 weeks |
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What are normal vital signs for a newborn? (HR, RR, BP)
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HR = 100-160
RR = 30-60 (with periodic breathing) BP = 65/30 to 90/60 |
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With a newborn physical exam, what are 3 things to look for in assessing their skin?
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-Perfusion: cyanosis, acryanosis, mottling
-Birthmarks: hemangiomas, mongolian spots - Jaundice (it's pathologic within 1st 24 hours of life) |
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With a newborn physical exam, what are 3 things to look for in assessing their HEENT?
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Head (fontanelles, caput vs. cephalohematoma)
Eyes: red flexes, subconjunctival hemorrhage Throat/mouth: cleft lip/palate, natal teeth |
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With a newborn physical exam, what are 3 things to look for in assessing their heart? (the 3 Ps)
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PDAs, PACs, pulses:
Murmurs (PDA closure) Arrhythmias (PAC's) Cardiovascular (femoral pulses) |
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With a newborn physical exam, what are some things to look for in assessing their lungs?
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Grunting, flairing, retracting
breath sounds - symmetry |
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With a newborn physical exam, what are 3 things to look for in assessing their abdomen?
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- Umbilical cord: 2 arteries - 1 vein
- Omphalocoele or gastroschisis (intestines poking out of belly button) - Anus: patent (open) or imperforate (no butthole or blocked butthole) |
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With a newborn physical exam, what are things to look for in assessing their genitalia? (male, female... other... yeah)
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males: hypospadius (undescended testes)
Female: vaginal discharge Ambiguous genitalia... seriously... yikes |
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With a newborn physical exam, what are things to look for in assessing their hands/feet/hips/clavicle?
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Hips: ortolani/barlow maneuvers (DHD)
Feet/hands: Clubfoot, metatarsus adductus, polydactyly (extra digits), syndactyly (webbed digits) Clavicle fracture with trauma |
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With a newborn physical exam, what are things to look for in assessing their neurologic function? Including spine/back?
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-Tone, reflexes, nerve palsies (brachial plexus)
-Jitteriness, irritability -Spine/back: sacral dimple |
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How frequent are major congenital abnormalities in newborns (% of live births, % of perinatal/neonatal deaths)?
-What are some examples of dysmorphologies/syndromes? |
1.5% of live births have major congenital defects.
15-20% of perinatal/neonatal deaths due to this. -Ex. Trisomy 21, neural tube defects |
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What are 3 examples of prophylactic measures for newborns?
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- Ophthalmic prophylaxis
- Vitamin K (prevents hemorrhagic disease of newborn) - Hepatitis B Vaccine (add HBIG if mother is HbsAg (+) withing 12 hours) |
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Name 2 examples of newborn screening?
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-Oto-acoustic emissions (OAE)
-Newborn metabolic screening (PKU, hypothyroidism, galactosemia, hemoglobinopathies). FYI: in 2006 expanded to 36 disorders!... Utah added Cystic Fibrosis in '09. -Repeat at 2 weeks |
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Name some benefits of breast feeding for newborns?
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- They get host resistance factors (IgE, IgA)
-Decreases URI, GI infections in infancy -Enhances neurodevelopment outcome |
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What's normal weight loss for a newborn? When should they return to normal birthweight?
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- up to 7-10% is acceptable
- should return to birthweight by 2 weeks |
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Upon discharging a newborn from the nursery, what are 4 things you should make sure the patients know?
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- Umbilical cord care
- Sleep position (back to sleep!) - Car seat... rear facing back seat - 1st routine office appointment at 2 days... then 2 weeks |
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What's the most common organism that causes neonatal sepsis? What are some other causes?
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-Group B Streptococcus
- E. Coli, strep viridans, staph aureus, enterococcus |
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What are some risk factors for neonatal sepsis? (~6 things)
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- Prematurity
- Prolonged rupture of membranes (>18 hrs) - Maternal fever - Maternal GB strep carriage - Hx of prior infant with GB strep disease - Increased risk with multiple births (twins/triplets) |
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What's the presentation of neonatal sepsis?
-What's the mortality rate of GBS sepsis? |
- Usually w/in 12-24 hours of birth
- Respiratory distress - Poor perfusion/hypotension - Temperature instability - Lethargy or hypotonia - Apnea - Poor feeding - (GBS) septis mortality = ~5% |
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What will the lab reports show in neonatal sepsis?
- What is the definitive Dx? |
- increased WBC (>30,000) or decreased (<10,000)
- Increased ratio of immature to mature neutrophils - Absolute neutrophil count (ANC <1,000) -Thrombocytopenia - Ches X-Ray: Infiltrates (pneumonia) - Definitive Dx = (+) blood culture |
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What's the Tx for neonatal sepsis?
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Ampicillin + gentamicin
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How frequent does jaundice occur in preterms?
- what percentage of infants are affected in 1st week of life? -At what serum level is jaundice noted? - Where does it start on the body and how does it progress? |
80% of the time
- 65% - 5 mg/dl - Starts on the head, progresses inferiorly |
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What presentation in a newborn would merit an evaluation for SEVERE jaundice?
-What lab values would merit this? |
-Jaundice in FIRST 24 hours of life
- if persists beyond 2 weeks - If any ill infant then gets jaundice - bilirubin increases 5 mg/dl in 24 hrs - Serum bilirubin > 15 or direct bilirubin > 1 mg/dl |
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What's the Tx for jaundice?
- Why treat? |
Phototherapy... can also do an exchange transfusion (if bilirubin is > 20-25)
- to avoid kernicterus (bilirubin encephalopathy) |
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Outside of treatment, what can you recommend to manage jaundice?
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- More frequent feedings (8-12 times daily)
ALSO: monitor and therapy using the Bhutani nomogram |
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Give 2 major problems arising from an infant from a mother with diabetes?
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- Macrosomia (large sized baby)
- Hypoglycemia (due to acclimation of higher glucose and insulin levels in utero) OTHERS: hypocalcenemia, polycythemia (high [hemoglobin] in blood) |
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Name a few difficulties that a premature child can have?
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- Difficulty maintaining their temperature
- hard to control respiration (apnea) - surfactant production is low... - holes in heart (PAD, PFO, etc) - poor suck, swallow and breathing - poor renal function - poor cerebral vasculature - more susceptible to infection |
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What is Transient Tachypnea of the newborn (TTN)?
-What's its Sx, CXR findings, Tx, prognosis? |
Retained amniotic fluid
Sx: respiratory distress first breaths of life CXR: fluid in interlobar fissures Tx: O2 support Resolves w/in 12-24 hrs. |
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What's Hyaline membrane disease (HMD)?
- Sx?, CXR findings?, Tx? |
It's surfactant deficiency.
Sx: respiratory distress in premature infants CXR: "Ground-glass" appearance Tx: O2 support, mechanical ventilation, and surfactant |
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What's Bronchial pulmonary dysplasia (BPD)? Sx? Tx:?
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Chronic lung disease that follows hyaline membrane disease and respiratory stress syndrome
Sx: persistent O2 needs Tx: O2 support, diuretics, bronchodilators, RSV prophylaxis |
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What's Necrotizing entercolitis (NEC)?
Sx? Tx? CXR findings? Complications with it? |
Intestinal necrosis (like my niece Chantel had) +/- perforation and affects distal ileum/proximal colon.
Sx: Abdominal distention, vomiting, bloody stools X-ray: air in bowel wall (Pneumotosis interstinalis) Tx: broad-spectrum antibiotics, surgery! Complications: interstitial perforation, sepsis (mortality ~10%) |
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What's intraventricular hemorrhage (IVH)?
Sx:, Complications |
ischemia, reperfusion and vessel rupture in areas of low cerebral blood flow.
Sx: lethargy, apnea, seizures, shock Complications: ventriculomegaly |
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WRESTLE WITH THE ALGORITHM ON PAGE 77...
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Okay? He told us to...
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DON'T forget to work with the algorithm on page 77....
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Sound good?... YOU'RE A HANDSOME MAN!
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What's the criteria for SIDS?
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Sudden unexpected death
- infant under 1 y.o. - death during sleep - unexplained after thorough evaluation including autopsy and review of Hx. |
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Risk factors for SIDS?
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Low birth weight
- Teenage mother - Maternal smoking/drug use - lack of breastfeeding - late or absent prenatal care - low SES (socioeconomic status) - Fam Hx |
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What are some things to avoid in child's sleep environment?
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- Sleeping on a soft surface (pillow, quilts, comforters)
- Any loose bedding (blankets or sheets) - Co-sleeping - Overheating - PUT THEM on their back! Avoid PRONE! BE supine. |
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what's the cause of SIDS?
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Not known...
Proposed hypothesis are: - delayed development of arousal or cardiorespiratory control (breastfed children get this) -Airway obstruction - Brain stem immaturity or injury |
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What's the relationship of APNEA and SIDS?
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none really... most kids with apnea don't die from SIDS. Most kids that died from SIDS don't have a Hx of apnea.
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What does positioning have to do with SIDS?
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INCREASED incidence of SIDS in infants with prone positioning. So......
"Back to sleep campaign"... (man he likes to plug things). |
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What are some consequences of non-prone (supine) sleeping?
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- No increase of aspiration
- delayed attainment of gross motor skills - increased incidence of occipital plagiocephaly (flattening out of back of head) |
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Who's most affected by SIDS?
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Infants 21 days - 9 months (peak of 2-4 months)
- happens mostly between midnight and 8 a.m. |
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What's ALTE?
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- Apparent Life Threatening Events
Examples: - RSV or bacterial infection - Cardiomyopathies.. - gastroesophageal reflux - seizure - CNS infection - Poisoning - munchausen syndrome |
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What's the presentation of ALTE?
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Apnea
Color change Change in muscle tone Choking or gagging |
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How do you manage ALTE?
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-hospitalize for observation
- do Dx by Hx and presentation - Create a Tx directed at underlying cause - TEACH PARENTS CPR! prior to discharge |
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Is apnea home monitoring beneficial?
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No proven results that it is beneficial.
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What's the incidence of child abuse?
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~2% of all U.S. children are abused/neglected annually
Nearly 1700 children die from child abuse every year!!!! :( Every 10 seconds, a child is reported abused or neglected. |
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Name some risk factors of abusive families?
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- Poverty/economic strain (SES)
- Unmarried or teen mother - Substance abuse - Domestic violence FYI: 1/3 of abuse cases occur in EXTRAfamilial settings |
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What are some typical historical features with abuse cases?
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- Discrepant Hx (Hx doesn't match up)
- Delayed seeking care - Hx of abuse in caregiver's childhood - Stress in caregiver's family - Hx of caregiver losing control from child behavior |
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What are some clinical findings in a child that has been abused?
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- Multiple stages of healing
-abraisons, alopecia (hair loss), bites, bruises, burns, dental trauma, fractures, lacerations, ligature (strangulation) marks or scars. |
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What's the most common manifestation of physical abuse?
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Suspicious bruises
-i.e. genitals, ears don't usually get bruised. They'll have multiple bruises of varied ages and may be patterned (like belt, pinch or cord marks) - ANY bruise in a non-ambulatory patient raises concern! |
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What are some signs of abusive burning on a child?
FYI: 25% of all pediatric burns are due to abuse!!!! CRAZY! |
- Any burn with circumferential, sharply demarcated edges ('stocking-glove distribution)
- Absence of splash marks in an immersion burn (bath tub) - Cigarette, curling iron type burns |
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What should you think of when you see a rib fracture?
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ABUSE!
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IMPORTANT!
What's the triad for Shaken Baby Syndrome? What's the outcomes? |
1) Severe intracranial injury
2) Retinal hemorrhages 3) with minimal or no external signs of trauma Outcome: 1/3 death, 1/3 permanent neurological sequelae, 1/3 'normal' |
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What are some indications of head and skeletal trauma in an abused child?
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Fractures in multiple stages of healing, and ones in specific bones (ribs, sternum, scapula, vertebrae)
- Subdural hemorrhages, retinal hemorrhages (usually bilateral) |
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What should you do if a child presents with skeletal or head trauma?
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Obtain a skeletal survey after any suspicious fracture (repeat survey in 2 weeks)
- obtain an ophthalmology consult |
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What organ is most commonly injured in abdominal trauma during child abuse?
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LIVER!!!!
Other organs injured are pancreas, small bowel, duodenum. |
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What's the 2nd leading cause of death in child abuse cases?
What type of imaging do you want to order if a child presents with this? |
- Abdominal trauma (mortality approaches 50%!!!!!!!!!)
Imaging = CT scan |
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What do sexually abused patients present with?
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NOTHING! (in 95% of patients there are no physical findings)
BUT: can have, - STDs, Sleep disturbance, difficulty holding bladder when toilet trained, recurrent genital or anal pain, phobias, sexual behaviors... etc (pg. 95) |
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What are some common presentations for emotional abuse?
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- Eroded child's self esteem
- Sleep disturbances, witness abuse headache and abdominal pain, avoidance behaviors (avoids being with parent's or uncle's house... or whoever!) |
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What are 3 categories of child neglect?
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- Emotional (no apparent child-parent attachment)
- Physical (not giving food, clothing etc) - Medical (not providing medical care) |
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What is failure to thrive (FTT), and what are some presentations of it?
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Someone is not providing enough nutrition to this child for their need.
- Marked growth deceleration (preservation of head circumference), loss of subcutaneous fat, Hx of social risk factors (family dysfunction, substance abuse) - Often reverses when child is placed with a new caregiver. |
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What's Munchausen Syndrome?
- Who is usually the perpetrator? |
"Fastitious Disorder by Proxy" Caregiver creates signs/symptoms of illness in child (like on the 6th Sense movie when they catch the mom poisoning her child)
- Mother 95% of the time |
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How do we manage abuse from Munchausen Syndrome?
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Immediately treat physical injuries!
- Establish a safe environment - MANDATORY reporting (child abuse hotline or a child protective service agency) - Use non-accusatory empathic actions. Remain objective and perform a open-ended question interview. - Investigation by social services and law enforcement |
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How do you prevent child abuse?
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- Use home health visitor to at-risk family
- Give education to parent regarding stress situations - Counsel mother about safe child care arrangements - Teach child about personal privacy (private parts, good touch and bad touch) - Educate parents about age-appropriate discipline |
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What is the definition of a child fever?
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T (rectal) > 38 degrees C (100.4 F)
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What are some causes of increased temperature?
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-Rise in hypothalamic set point (infection, cancer or collagen-vascular disease can cause hypothalmus disorders...)
- Body heat production exceeds heat loss mechanisms (malignant hypothermia) - Heat loss mechanisms are not working (ectodermal dysplasia) - Extrinsic heat sourses (hot weather, warm bath, excessive clothing, exercise) |
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What's the pathophysiology of a fever?
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- Infectious agent induces macrophages to release cytokines ==> endogenous pyrogen
- These interact with anterior hypothalmus ==> releases prostaglandins and other mediators - Prostaglandins increase metabolic rate ==> heat production, rise in core body temperature |
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What's the most common cause of a fever in a child?
- how long does it take to resolve? |
Viral infection.
- 3-4 days |
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At what temperature does a correlation between fever and serious bacterial infection occur?
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- When temp rises over 40 degrees C
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Can a fever cause brain damage?
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Apparently no... weird. I though it did.
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Is Matt a handsome man?
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YES! Much better than Coach Roscoe...
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What immediate evaluation should occur with a child presenting with a fever? (about 9 things...)
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- Age>3 months
- Fever Temp>40.6 C/ 105 F - Breathing is labored - Inconsolable crying - Child is difficult to arouse - Neck stiffness/sore (Nuchal rigidity) - Petechiae - Convulsion with fever - Child looks or act VERY sick! |
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How do you treat a childhood fever?
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- Check first for potential causes
- Use antipyretic therapy (goal is just to relieve discomfort, REDUCE temp) - Encourage more fluid intake - Limited sponging - tepid water |
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What are two drugs that can be used as antipyretics?
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- Acetominophen (tylenol)
- Ibuprofen (advil, motrin) |
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What drug should you AVOID as a fever treatment (antipyretic)?
- Why? |
ASPIRIN!
- Due to Reye's Syndrome. Can enhance fever risk due to influenza or varicella |
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What's important for you to identify in a child with a fever?
- What are examples of this? |
Serious Bacterial Infection (pg. 106)
- UTI (74%), Sepsis/bacteremia, meningitis, bacterial pneumonia, bacterial gastroenteritis, bone/soft tissue infections (osteomyelitis, septic arthritis, abscess) |
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What does "fever without a source" mean?
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Acute febrile illness, cause of fever is not apparent after a careful Hx and examination.
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What does "lethargy" mean?
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Altered level of consciousness.
- Decreased eye contact or level of interaction |
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What are some signs of toxicity in a child?
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- LETHARGY! but also... poor perfusion, cyanosis, hyper/hypo-ventillation
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What does "occult bacteremia" mean?
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When child isn't toxic appearing clinically, and has the presence of bacterial pathogens in blood.
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What does "sepsis" mean?
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Presence of bacteria in blood of a patient that is ALSO toxic!
-Different from occult bacteremia |
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What's a risk with hypothermia (temp < 36C)?
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severe bacterial infection (SBI)
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What's the correlation between an increase in fever and SBI?
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As fever increases, SBI risk increases.
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If a child age 1-90 days old presents with a fever and is toxic, what percentage of risk for SBI do they have?
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17%
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If a child age 1-90 days old presents with a fever and is not toxic, what percentage of risk for SBI do they have?
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9%
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If a child age 1-90 days old presents with a fever and is "low risk", what percentage of risk for SBI do they have?
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1.4%
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What's the Rochester criteria for low-risk infants? (page 108) ... this is stupid...
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It evaluates febrile infants < 60 days old that...
- have non-toxic appearance - were previously healthy - No skin, soft tissue, bone, joint or ear infection noted - have WBC: 5000-15,000 with <1500 bands (WBC count > 15,000 increases bacteremia risk 3 fold) - Urinalysis < 10 WBC/hpf |
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What is the most common pathogen in severe bacterial infection (SBI) fever?
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E. Coli (page 108)
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How do you manage a 1-30 day old child with severe bacterial infection (SBI) fever? (3 steps)
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1) Full sepsis workup
2) Hospitalize 3) IV antibiotics, pending culture results (ampicillin + cefotaxime and gentamicin)... if meningitis is suspected: triple the coverage. If just uti, then do the first two. |
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How do you manage a 30-90 day old child with severe bacterial infection (SBI) fever? (2 steps) [think high and low risk]
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1) If doesn't meet low risk criteria:
a) sepsis work-up, hospitalize, iv antibiotics 2) If low risk a) sepsis work-up, out patient antibiotics and follow-up in 24 hours b) Urine culture only, outpatient observation w/ no antibiotic, follow-up in 24 hours. |
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If a 28-90 days old child presents with a fever, and if WBC & differential urinalysis/stool exam (if diarrhea) comes back with positive labs, what should you do next? (algorithm on page 109)
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Admit them
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If a 28-90 days old child presents with a fever, and if WBC & differential urinalysis/stool exam (if diarrhea) comes back with negative labs, what two options do you have? (algorithm on page 109)
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Option A: Perform a urine culture, blood culture, CSF culture, give ceftiaxone and return in 24 hours
Option B: Urine culture, and observation |
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If a 28-90 days old child presents with a fever, and you receive a positive CSF culture, how do you manage that?
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Admit them, give IV antibiotics (ampicillin + gentamicin + CEF)
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If a 28-90 days old child presents, and you receive a positive blood culture, how do you manage that?
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If it's S. pneumonia (non-resistant) and patient is stable (afebrile): give ceftriaxone (IM), then oral amoxicillin x 10 days
- If a different pathogen, admit, IV antibiotics (ampicillin + CEF) |
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If a 28-90 days old child presents, and you receive a positive urine culture, how do you manage that?
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If afebrile w/o bacteremia, give oral antibiotic (cefdinir) x 10 days
- If febrile or bacteremic, admit and iv antibiotics (ampicillin + CEF)/ (ceftriaxone if > 60 days) |
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If a 28-90 days old child presents with a fever, and if WBC & differential urinalysis/stool exam (if diarrhea) comes back with positive labs, what should you do next? (algorithm on page 109)
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Admit them
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If a 28-90 days old child presents with a fever, and if WBC & differential urinalysis/stool exam (if diarrhea) comes back with negative labs, what two options do you have? (algorithm on page 109)
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Option A: Perform a urine culture, blood culture, CSF culture, give ceftiaxone and return in 24 hours
Option B: Urine culture, and observation |
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If a 28-90 days old child presents with a fever, and you receive a positive CSF culture, how do you manage that?
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Admit them, give IV antibiotics (ampicillin + gentamicin + CEF)
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If a 28-90 days old child presents, and you receive a positive blood culture, how do you manage that?
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If it's S. pneumonia (non-resistant) and patient is stable (afebrile): give ceftriaxone (IM), then oral amoxicillin x 10 days
- If a different pathogen, admit, IV antibiotics (ampicillin + CEF) |
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If a 28-90 days old child presents, and you receive a positive urine culture, how do you manage that?
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If afebrile w/o bacteremia, give oral antibiotic (cefdinir) x 10 days
- If febrile or bacteremic, admit and iv antibiotics (ampicillin + CEF)/ (ceftriaxone if > 60 days) |
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What's the correlation with fever over 41 degrees and risk of occult bacteremia in infants 3-36 months?
- What's the common pathogen associated with a fever in this age group? |
risk increases
- E. coli... again! |
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How do you manage a fever in a child age 3-36 months? (hint: look at it with a fever over 39 toxic and non-toxic and under 39 degrees... what do you do?)
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1st: eliminate from consideration patients with obvious viral infection or those with a defined source (like Ottits Media)
-THEN: for fever < 39, evaluate, antipyretics, and follow-up - For fever > 39: IF TOXIC (or immuniodeficient)... admit, septic work-up, IV antibiotics IF NON-TOXIC use the screening tests! (these are described later on) |
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What are the screening tests used for non-toxic febrile (>39 degrees) children ages 3-36 months? (5 things)
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-WBC
- Blood culture - Urinalysis/Urine culture - Chest X-Ray - Stool culture Read page 111 of syllabus to understand details of these. |
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What are some management decisions that you need to make with a febrile child (>39 degrees) age 3-36 months?
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Get CBC... if WBC is > 15,000, obtain BCx and treat with ceftriaxone
- get Urine culture: in all females and males to check for UTI - Get chest X-ray or stool culture if clinically indicated |
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IF a child age 3-36 months gets a positive blood culture, what should you do?
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If afebrile with S. Pneumoniae, give ceftriaxone, then amoxicillin x 10 days
- If febrile, ill or non-S. pneumoniae: repeat blood culture, obtain CSF culture and admit for IV antibiotics |
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If a child age 3-36 months has a positive urine culture, what do you do?
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If afebrile: oral antibiotics x 10 days
If febrile or ill: admit for IV antibiotics. |
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IF a child over 90 days presents with a fever over 39 degrees and a WBC count under 15,000... what would you do?
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Just observe
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IF a child over 90 days presents with a fever over 39 degrees and a WBC count over 15,000... what would you do?
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Get a blood culture and treat with ceftriaxone.
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