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13 Cards in this Set
- Front
- Back
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What is a potential side effect of St. John's wart in a teen who is using it for depression?
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She will need further backup contraception, because it increases elimination of P-450 meds which includes all OCPs.
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Which of these meds will be have decreased effect due to St. John's wort?
A) Digoxin B) OCP C) Anticoagulants D) HAART E) Iron F) All of the above |
F. It acts like an SSRI and increases elimination of P-450 meds
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What is echinacea used for? Who is it contraindicated in?
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URI prevention by modulating cellular immunity, so don't use it in immunocompromised.
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What is the side effect of valerian root?
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It is sedating, so don't use with alcohol or other sedatives.
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What is the percentage of kids who have a skin reaction to PCN who will have reaction to cephalosporin?
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< 10%
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A patient has recently been on ceclor and now presents with fever, LAD and joint aches. What is this?
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Serum sickness
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A 15yo boy is on metoprolol for history of SVT. His SVT does not seem to be responding to treatment. What is the most likely reason?
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Side effect of sexual dysfunction...non-compliance.
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What is the mechanism of action and resulting side effect of acetazolamide?
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It is a carbonic anhydrase inhibitor which blocks reuptake of bicarbonate and thus causes alkaline urine and metabolic acidosis.
"Acid Soul Amide" |
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What are the mechanism of action and resulting electrolyte side effects of lasix?
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Blocks Na and Cl absorption and causes wasting of calcium, K+ and H+. Thus it causes metabolic hypokalemic alkalosis
Picture Lasix in the great Hoop (I mean loop) of Henle. H hops out and the X knocks out K, Kloride and Kalcium...hypokloremic, hypokalemic alkalosis |
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Are the ototoxicity and renal toxicity of lasix dose dependent?
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Yes
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What is the mechanism of action and resulting side effect of HCTZ?
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Sodium and Chloride is lost at distal tubule. At distal tubule, you also lose water and keep bicarb instead of chloride...contraction and metabolic alkalosis
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How does mannitol work?
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It pulls fluid from cells to vessels and blocks fluid reabsorption at the kidneys.
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What is the mechanism of action and resulting side effect of spironolactone?
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Sodium is spiraled out while potassium is takin in. Potassium sparing. It does cause gyecomastia because of estrogen like effect.
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