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20 Cards in this Set

  • Front
  • Back
What is the broad definition of disease?
Disruption from homeostasis
What is homeostasis?
The maintenance of a nearly stable internal environment, where metabolic functions proceed at maximum efficiency.
What is the cytological explantion for drug tolerance?
Repeated use causes the smooth ER to proliferate in an effort to detoxify these drugs and protect the cell. The more smooth ER you have, the more drugs you can handle.
What is vitamin A intoxification?
Excessive consumption of vitamin A may cause lysosomal membranes to rupture, releasing the hydrolytic enzymes into the cytoplasm of cells with the subsequent destruction of the intracellular material.
What causes lysosomal membranes to rupture, releasing the hydrolytic enzymes into the cytoplasm of cells with the subsequent destruction of the intracellular material.
Vitamin A intoxification
What is rheumatoid arthritis?
Pain which is due to the release of enzymes by the lysosomes into the joint capsule and the digestion of the surrounding tissue.
What causes pain which is due to the release of enzymes by the lysosomes into the joint capsule and the digestion of the surrounding tissue.
Rheumatoid arthritis
What is Atrophy of the uterus?
The normal regression or atrophy, in size of the uterus following childbirth is due to lysosome digestive activity. These same lysosomes cause the regression in mammary tissue after weaning of an infant.
What is "Down's syndrome"?
There is an extra chromosome 21. This condition is also called trisomy-21 or mongolism. It is characterized by mental retardation, a small skull, short flat nose, and short fingers.
What is it called when there is an extra chromosome 21. This condition is also called trisomy-21 or mongolism. It is characterized by mental retardation, a small skull, short flat nose, and short fingers.
Down's syndrome.
What are inherited diseases?
Diseases that result from defective genes that are passed from parent to offspring. Many are caused from a single base change in the DNA which results in a change of the mRNA codon.
What are diseases that result from defective genes that are passed from parent to offspring. Many are caused from a single base change in the DNA which results in a change of the mRNA codon.
Inherited diseases
What is Leukemia?
a malignant blood disease in which there is a tremendous increase in the number of leukocytes. These leukocytes are immature and incapable of fighting infection.
What is a malignant blood disease in which there is a tremendous increase in the number of leukocytes? These leukocytes are immature and incapable of fighting infection.
Leukemia
What is Leukopenia?
Decreased produciton of WBC's; caused by radiation, drugs or chemicals.
What causes a decreased produciton of WBC's; caused by radiation, drugs or chemicals.
Leukopenia
What is Thrombocytopenia?
Is abnormally low number of platelets (below 50,000) and causes excessive bleeding.
What causes abnormally low number of platelets (below 50,000) and causes excessive bleeding.
Thrombocytopenia
What is Thrombocytopenia purpura?
Bleeding from many small vessels causing the skin to display many small, purplish blotches
What is Erythroblastosis fetalis?
hemolytic anemia in the newborn Rh positive baby caused by maternal antibodies against the Rh factor tthat have crossed the placenta.