Pda I Final

Front 1

Class IA Antiarrhythmics

Back 1

Moderate potency Na+ blockers
Also block K+ channels
Inc refractoriness and AP duration
Inc QRS and QT
Dec conduction velocity
FOR: Atrial and Ventricular arrhythmias

Front 2

Class IB Antiarrhythmics

Back 2

Low potency Na+ blockers
Dec automaticity
Inc refractoriness
Shortens AP
Inc QRS but not QT

Front 3

Class IC Antiarrhythmics

Back 3

High potency Na+ blockers
Dec phase 0 and AP conduction
Inc AP duration
Inc QRS and PR intervals

Front 4

Class IA Antiarrhythmic

Back 4

Procainamide

Front 5

Class IA Antiarrhythmic

Back 5

Quinidine

Front 6

Class IA Antiarrhythmic

Back 6

Disopyramide (NORPACE)

Front 7

Class IB Antiarrhythmic

Back 7

Lidocaine

Front 8

Class IC Antiarrhythmic

Back 8

Flecainide

Front 9

Class IC Antiarrhythmic

Back 9

Propafenone (RHYTHMOL)

Front 10

Class II Antiarr.

Back 10

Propranolol (INDERAL)

Front 11

Class II Antiarr

Back 11

Sotalol (BETAPACE)

Front 12

Class II Antiarr

Back 12

Esmolol (BREVIBLOC, B1)

Front 13

Class III Antiarr

Back 13

Amiodarone

Front 14

Class III Antiarr

Back 14

Dronederone

Front 15

Class IV Antiarr

Back 15

Verapamil

Front 16

Class IV Antiarr

Back 16

Diltiazem

Front 17

Simulates adenosine receptors

Back 17

Adenosine

Front 18

Inc AV node refractoriness

Back 18

Digoxin

Front 19

Induces labor in last trimester
Promotes milk letdown

Back 19

Oxytocin (Pitocin)

Front 20

Synthetic arginine vasopressin - used when there is impaired renal conservation of water due to inadequate vasopressin (diabetes insipidus)

Back 20

dDAVP

Front 21

Non-endocrine systemic use of glucocorticoids, treat inflammation

Back 21

Prednisone, Methylprednisone

Front 22

Drug for menopause - estrogen conjugated to a sulfate ester

Back 22

PREMARIN

Front 23

Drug for menopause, conjugated estrogen and progestin

Back 23

PREMPRO, PREMPHASE

Front 24

Drug for menopause, synthetic conjugated estrogen, chem. modified from plants

Back 24

cenestin (DURAMED)

Front 25

SERM, first generation
-estrogen antag in breast
-estrogen agonist in bone, lipid profile, and uterus

Back 25

Tamoxifen (NOLVADEX)

Front 26

SERM, second generation
-estrogen antag at breast, uterus, and blood vessels
-estrogen agonist at bone and lipid profile

Back 26

Raloxefine (EVISTA)

Front 27

Progestin, most androgenic activity

Back 27

Norgestrel

Front 28

Progestin, moderate androgenic activity

Back 28

Norethindrone

Front 29

Progestin, least androgenic activity

Back 29

Norgestimate

Front 30

IM Injection of medroxyprogesterone every 3 months

Back 30

DEPOPROVERA

Front 31

Competitive antagonist of progesterone receptor, Abortifacient

Back 31

Mifepristone (RU486)

Front 32

Levonorgestrel, to be taken within 72 hrs of unprotected sex

Back 32

Plan B

Front 33

Fertility drug
-Estrogen agonist at hypothalamus, AP, and ovary
-Increases GnRH secretion

Back 33

Clomiphene (CLOMID)

Front 34

Fertility Drug
-GnRH analog given in pulses and cause release of LH/FSH

Back 34

Gonadorelin (FACTREL)

Front 35

Fertility Drug
-FSH and LH

Back 35

PERGONAL

Front 36

Fertility drug
-Just FSH

Back 36

METRODIN

Front 37

IM injections of replacement androgens 2-3x per week

Back 37

Testosterone, Testosterone Propionate

Front 38

IM injecttions of replacement androgens every 2-4 wks

Back 38

Testosterone Enthanate, Testosterone Cypionate

Front 39

Replacement androgens, orally active

Back 39

Methyl Testosterone, Fluoxymesterone

Front 40

Patches of testosterone

Back 40

Testoderm, Androderm

Front 41

Cream version of testosterone

Back 41

Androgel

Front 42

Treatment for BPH
-Inhibits 5-alpha reductase

Back 42

Finasteride (PROSCAR, PROPECIA)
Dutasteride (AVODART)

Front 43

Alpha 1 adrenergic receptor antagonists for BPH
-can be used with finasteride

Back 43

Prazosin, Terazosin, Tamsulosin

Front 44

Androgen antagonist, blocks androgen receptor to help BPH

Back 44

Flutamide (EULEXIN)

Front 45

Synthetic T4, converted to T3 by body
-to help hypothyroidism

Back 45

SYNTHROID

Front 46

To treat hyperthyroidism, inhibits production of thyroid hormones

Back 46

Methimazole

Front 47

To treat hyperthyroidism
-Dec thyroid peroxidase rxns
-Dec periph deiodination

Back 47

Propylthiouracil

Front 48

Drug becomes incorporated into bone, decreases osteoclast activity and number of osteoclasts

Back 48

Bisphophonates (-ronates)

Front 49

Drug therapy for osteoporosis, maintains bone mass, decreases fractures (~60%)

Back 49

Calcitonin (Miacalcin, Calcimar)

Front 50

Drug therapy for osteoporosis, estrogen agonist
-Decrease bone loss, decrease fractures (~40-50%)

Back 50

SERMS (Osteopor)

Front 51

1st 34 AAs of PTH
SQ, low dose
9-13% increase in bone mass density
Approved for ~2yrs - in rats causes bone tumors

Back 51

Teriparatide (FORTEO)

Front 52

Somatostatin analogue
-3 SQ injections/day

Back 52

Ocreotide (SANDOSTATIN)

Front 53

Somatostatin analogue
-Slow release, IM every 4 wks

Back 53

SANDOSTATIN LAR

Front 54

Somatostatin analogue
-IM every 10-14 days,

Back 54

lanreotide (SOMATULINE LA)

Front 55

Dopamine agonist, used to treat excess GH - dec. GH secretion

Back 55

Bromocriptine (PARLODEL)

Front 56

A GH antagonist that binds GH but doesn't activate phosphorylation signaling cascade

Back 56

Pegvisomant (SOMAVERT)

Front 57

Idential to human GH plus one AA, treat deficient GH

Back 57

Somatrem (PROTROPIN)

Front 58

Identical to human GH, treat deficient GH

Back 58

Somatropin (HUMATROPE)

Front 59

Synthetic GHRH - NOT effective if AP is defective

Back 59

Sermorelin Acetate

Front 60

Synthesizes and releases aldosterone

Back 60

Zona Glomerulosa - Adrenal cortex

Front 61

Synthesizes and releases androgens and glucocorticoids (mostly cortisol)

Back 61

Zona Fisciculata - Adrenal cortex

Front 62

Synthesizes and releases androgens and glucocorticoids (mostly DHEA)

Back 62

Zona Reticularis - Adrenal Cortex