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93 Cards in this Set
- Front
- Back
What are the 4 types of glial cells in the Central Nervous System?
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Astrocytes, Oligodendrocytes, Microglia, Ependymal Cells
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Astrocytes
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1. Physically support neurons in proper spatial relationships
2. Serve as a scaffold during fetal brain development 3. Induce formation of blood-brain barrier 4. Form neural scar tissue 5. Take up and degrade released neurotransmitters into raw materials for synthesis of more neurotransmitters 6. Take up excess K+ to help maintain proper brain ECF ion concentration and normal neural excitability 7. Enhance synapse formation and strengthen synaptic transmission via chemical signaling with neurons |
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Oligodendrocytes
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the plasma membranes of oligodendrocytes serve as an insulator around axons- allows for action potentials to be transmitted faster
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Microglia
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Play role in defense of brain as phagocytic scavengers-they are motile in response to chemical signals
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Ependymal cells
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1. Serve as neural stem cells with the potential to form new glial cells (and neurons in the hippocampus)
2. Line internal cavities of brain and spinal cord 3. Contribute to formation of cerebrospinal fluid |
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How many cranial neurons are there?
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12
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How many spinal neurons are there?
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31
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What is the Cauda Equina?
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a thick bundle of nerve roots at lower vertebral canal
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How many cervical neurons are there?
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8
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How many thoracic neurons are there?
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12
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How many lumbar neurons are there?
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5
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How many sacral neurons are there?
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5
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How many coccygeal neurons are there?
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1
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What are the functions of the cerebral spinal fluid?
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shock absorption, brain floating, and some circulation.
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Where is the cerebral spinal fluid?
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fills ventricles and subarachnoid space
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How is anything transported through the tight junctions of the blood-brain barrier?
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It has to be lipid soluble so it can diffuse through the cells. It has to be carried through the blood.
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Where is the primary motor cortex located?
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In the frontal lobe of the cerebral cortex.
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what is the function of the thalamus?
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relay synaptic input and motor pathways.
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What are the functions of the hypothalamus?
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# Regulation of many homeostatic functions: Body Temperature, Thirst, Urine Output, Food intake
# Emotion # Basic Behavior patterns # Role in Sleep-Wake Cycle # Regulates Anterior pituary Function (Growth, Sexual function, Stress Hormone Release, Lactation, Thyroid Function) # In class he discussed that it produces and secreates nuerohormones |
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What are the functions of the Basal Nuclei?
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# Inhibition of muscle tone
# Coordination of slow, sustained movements # Suppression of useless patterns of movement # Dysfunctions-resting tremors (Parkinsons disease); muscular rigidity |
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What are the functions of the cerebellum?
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* subconscious control of motor activity
* monitors and makes corrective adjustments in motor activities elicited by other parts of the brain * compares actual position and rate of change of position with intentions * used in skilled voluntary muscle activity, stores procedural memories * vital role in maintaining balance. |
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Oculomotor nerves-
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efferent- controls skeletal muscles that move eyeball up, down, and medially, muscle that raise upper eyelid, and controls smooth muscle that constrict pupil and alters lens shape for near and far vision
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Olfactory nerves-
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afferent nerve- carries sensory input from receptors in olfactory (smell) neuroepithelium
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Optic nerves
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afferent nerve- carries sensory input from receptors in eye
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Trigeminal nerves-
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1. efferent- innervates skeletal chewing muscles 2. afferent- transmits information from receptors in skin, skeletal muscles of face, nose, and mouth, and teeth sockets.
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Vagus nerves-
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1. efferent-innervates skeletal muscles of pharynx and larynx, and smooth muscle and glands of thorax and abdomen 2. afferent- transmits information from receptors in thorax and abdomen.
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Vestibulocochlear nerves
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-afferent- transmits information from receptors in ear
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Sensory Receptor-
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an afferent neuron's peripheral ending which is specialized to respond to a particular stimulus in its environment.
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Receptor Site-
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membrane protein that binds with a specific extracellular chemical messenger
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Mechanoreceptors-
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sense tension. i.e. stretching or bending
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Nociceptors-
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sense pain
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Photoreceptors-
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sense light.
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Acetylcholinesterase-
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enzyme that breaks down ACh to Cholin and acetate at the neuromuscular junction in a muscle fiber.
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where is cerebrospinal fluid formed?
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at the choroid plexus by ultrafiltration of the blood.
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How is the blood-brain barrier formed?
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By astrocytes and tight-junctions between the capillary cells.
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What are the special senses.
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# Taste
# Smell # Vision # Balance # Hearing |
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Sleep Stage 1 -
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transition between sleep and wakefulness, eyes begin to roll, lasts only a few minutes
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Sleep Stage 2
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peaks of brain waves become higher, lasts only a few minutes
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Sleep Stage 3
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20-50% slow brain waves (delta waves) aka "Delta Sleep"
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Sleep Stage 4
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same as stage three but more than 50 % delta waves
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Sleep Stage 5
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frequent bursts of rapid eye movement, vivid dreaming, muscle twitches
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Slow-Wave Sleep Stage
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1. Consists of first four stages and accounts for 80% of sleep.
2. Dreams are rare 3. Decreased blood pressure, heart rate, respiration 4. EEG slow waves .5-2/second |
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REM Sleep Stage
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1. Occurs every 90 minutes and lasts 5-30 minutes
2. Active dreaming (remembered) 3. Muscle tone depressed 4. Brain highly active- EEG comparable to an awake person 5. Asleep with active EEG=Paradox |
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ascending tract
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afferent nerves
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descending tract
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efferent nerves
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What are the components of a reflex arc.
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1. Stimulus (hammer on knee @ doctor's office)
2. Sensory Receptor: 1. Sensitive to changes in the internal or external environment 2. Generates action potentials in the sensory neuron 3. Sensory Neuron(Afferent): 1. Neuron associated with the receptor that transmits impulses to the CNS 4. CNS Integrating Center(Inter-Neuron): 1. Sensory information is received and meaningful responses generated 5. Motor Neuron(Efferent): 1. Transmits the action potential to the muscle 6. Effector Organ(Muscle): 1. Muscle that responds by contracting |
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What are the cranial nerves?
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Olfactory, optic, occulomotor, trigeminal, vagus, vestibulocochlear
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What are the monosynaptic reflexes?
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muscle spindle stretch reflex
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What are the polysynaptic reflexes?
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all other reflexes besides muscle spindle stretch.
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What is the autonomic nervous system?
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it is the system that controls the visceral organs and is comprised of the sympathetic and para sympathetic systems.
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What is the somatic nervous system?
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It is the system that controls voluntary movement of skeletal muscles and motor neurons.
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What does the brain need to make ATP?
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glucose and oxygen
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Perception:
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Mental awareness of sensory stimulation; occurs when the cerebral cortex interprets the meaning of sensations
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Sensation:
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Conscious or subconscious awareness of the external environment or internal conditions of the body
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what are the four conditions necessary to generate a sensation?
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1. stimulus
2. stimulus converted into A.P. 3. impulse must travel to brain 4. brain must integrate impulse into a sensation |
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Phasic Receptors:
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sensory receptors that adapt almost completely to stimuli after a period of time
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Tonic receptors:
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sensory receptors that adapt only partially
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Pitch
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tone or frequency; a low note will have low frequency, where as a high note will have high frequency
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Intensity
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(loudness) depends on amplitude; a sound with a small amplitude will be soft and a sound that has high amplitude will be loud
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Timbre:
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(quality) depends on overtones; timbre allows us to distinguish between the sounds of a saxophone and a trumpet
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Tympanic membrane-
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receives vibrations from the ear canal and passes it into the inner ear
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Malleus/Incus/Stapes-
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help pass vibrations to the inner ear; they preserve the frequency of a stimulus while amplifying it
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Oval window
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stapes vibrates through the oval window which creates vibrations through fluid in the cochlea
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Perilymph-
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the fluid in the cochlea that ripples
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Endolymph
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fluid in the cochlear duct
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Hair Cells in the cochlear duct
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are immersed in endolymph; they rub against an overhanging membrane which produces a receptor potential
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What is the order of the structures of the ear?
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1. tympanic membrane
2. Maleus/incus/stapes 3. Oval window 4. Parilymph 5. Endolymph 6. Hair cells |
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What is the range of human hearing?
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20-20,000 Hz
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How do we descriminate between high and low frequency sounds?
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High freq. waves are discerned early in the cochlear duct while low freq. sounds are detected deeper in the duct.
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how is an AP transmitted at a neuromuscular junction?
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1 Ca voltage gated channels open and Ca rushes into neuron
2 ACh is released and goes to motor end plate 3 ACh opens chem channels in muscle cell causing diffussion of Na and K |
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What filaments are present in the I band of a sarcomere?
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actin only
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What filaments are present in the A Band of a sarcomere?
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myosin primarily, actin also
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What filaments are present in the H zone of a sarcomere?
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myosin only
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What filaments are present in the M line of a sarcomere?
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myosin only-no cross bridges
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what is muscle tension?
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the constant subconscious tensing of muscles to keep balance.
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Lubb
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Closure of artioventricular valves
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Dubb -
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closure of semilunar valves: The Pulmonary valve and the Aortic valve
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P Wave -
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atrial depolarization
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QRS complex -
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ventricular depolarization
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t-wave
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ventricular repolarization
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Mean arterial pressure=
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1/3 sys + 2/3 dias or, dais+ 1/3 pulse pressure
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Arterial pressure=
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Cardiac output X Total peripheral resistance.
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Systemic veins volume
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64%
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Systemic arteries volume
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13%
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Pulmonary vessels volume
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9%
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Heart volume
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7%
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Systemic capillaries volume
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5%
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Systemic arterioles volume
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2%
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Where is the cerebral spinal fluid formed?
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in the coroid plexus
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What center of the brain controls breathing, digestion, circulation?
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the brainstem
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What's weird about the primary motor cortex?
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the left side controls the right side of body and vis versa.
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What center of the brain performs preliminary processing?
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the thalamus
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What is the ideal serving temperature for Dry Sherry and Dry Madeira?
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43-47 degrees F
6-8 degrees C |