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81 Cards in this Set
- Front
- Back
Describe the structure of Triglycerides
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Have a glycerol backbone, and 3 fatty acid chains attached to each carbon in the glycerol backbone..
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Steroids
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Are lipids, but are circular (the structure consists of 3 hexagons and one pentagon). Examples are Cholesterol, Sex hormones, Adrenal Cortical hormones, and vitamin D derivatives
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disaccharides
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sucrose, maltose, lactose
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polysaccharides
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glycogen or starch
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What can Glycerol and fatty acids join to form?
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triglycerides
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pH of urine =
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6.0
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pH of semen =
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7.5
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pH of blood =
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7.4
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pH of vaginal secretions =
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acidic
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molecules that have polar bonds- may contain O-H groups or S-H groups are hydro________?
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philic
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molecules that have long carbon chains are hydro________?
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phobic
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Nearnst equation
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Ek = 62mV log (k+)b / (k+)a
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Differentiation:
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Process by which cells become specialized to carry out specific functions
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Skeletal:
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* Bones
* Structure, Movement |
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Muscular:
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* Muscles
* Movement |
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Nervous:
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* Brain (i.e. memory)
* Spinal Cord * Nerves * Sensory, Regulation of everything |
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Integument
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* Skin
* Maintain body temperature |
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Immune / Lymphatic:
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* White blood cells
* Spleen, thymus, lymph nodes and liver |
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Digestive:
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* Mouth, esophagus, stomach, small intestine, large intestine / colon
* obtain energy and nutrients from food |
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What are the 11 body systems
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Reproductive
Urinary Circulatory Respiratory Endocrine Digestive Immune (Lymphatic) Integument (Skin) Nervous Muscular Skeletal |
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Respiratory:
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* trachea, lungs
* gas exchange |
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Endocrine:
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* Pituitary, thyroid, thymus, adrenals, pancreas, ovaries / testes (aka gonads)
* send hormones throughout the body to maintain homeostasis - regulation |
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Urinary:
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* Kidney, bladder, urethra
* filter blood, pH balance |
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Circulatory:
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* heart, blood vessels
* pump blood to all the body, transport of important biomolecules |
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Reproductive:
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* Female: Mammary gland, ovary, ovarian tubes, uterus, vagina
* Male: Testes, prostate, penis |
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Epithelial Tissue:
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Tissue that forms protective barriers and line organs (i.e. skin, lining of digestive tract)
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Tissue Types:
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Muscle, Nerve, Epithelial, Connective.
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Types of Connective Tissue
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blood, bone, cartilage and adipose
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Largest cell
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Nerve
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Smallest Cell
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Sperm
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RER (rough endo reticulum) -
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contains ribosomes which synthesize proteins
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Ribosomes
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* the site of PROTEIN SYNTHESIS
* Two populations: Free ribosomes- manufacture proteins to be used in that cell, and RER ribosomes- manufacture proteins to be secreted from cell. |
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SER (smooth endo reticulum)
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- lacks ribosomes, proliferates in an effort to detoxify drugs, stores calcium
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golgi
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* Golgi apparatus is the site of protein and lipid modification, packaging and distribution
o Flattened membranous sacs o Modifications include phosphorylation and glycosylation |
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Lysosomes
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* Contain enzymes! that degrade cellular or extracellular debris
* Over 40 acid hydrolases have been isolated from lysosomes * "suicide packets" which (aid in programed cell death)transport enzymes, digestion by phagocytosis, and destruction of damaged and worn organelles |
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Peroxisomes
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* Membranous sacs containing enzymes
* degenerates potentially toxic molecules in cell * Produces then decomposes Hydrogen peroxide. * Changes chemical composition to water and oxygen * deals with cell's own wastes that could be harmful to cell |
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Mitochondrion
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* where energy for the cell (ATP) is converted from food to ATP
* Present in all body cells except red blood cells * through kreb's cycle energy sources( proteins, lipids, carbohydrates) are oxidized into CO2 and H2O |
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Vault
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* An Organelle in search of a definitive function
o Transport vehicle from nucleus to cytoplasm o hypothesized to inadvertantly defend cancer cells- poliferate around nuclear envelope (many prevent anti cancer drugs from reaching the nucleus- number of vaults increases when drugs are administered) |
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Nucleolus
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Protein and rRNA
where ribosomes are made |
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What organelles are found in every body cell except red blood cells?
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Nucleus and mitochondria
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Micro tubules
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long hollow tubes made of tubulin- they coordinate cell movement, are components of cilia and flagella, serve as highways for cell transport, and form mitotic spindle fibers
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Microfilaments
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helical chains made of actin- they are important in cell contraction systems, and act as the mechanical stiffener in microvilli
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Intermediate filaments
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every other cytoskeletal component (very diverse)- generally, they provide structural support and relieve mechanical stress in cells.
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Membrane protein functions:
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1. Structural support 2. Transport (pores) 3. Enzymatic control of chemical reactions 4. receptors for hormones 5. cellular markers
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Membrane Carbohydrate functions:
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1. Repel charged objects 2. receptors 3. cell markers
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Microvilli-
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closely spaced finger-like projections, increase surface area for transport and absorption ex. intestine epithelial cells
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Stereocilli-
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long microvilli, functions: absorption (in male reproductive cell, absence=sterile), and sensory receptors (in inner ear- used for balance)
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Glycocalyx-
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fuzzy delicate coat of protein, glycoprotein, and or sugar residues that cover cell surface : function- protection and recognition (ex. cell marker)
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Cilia-
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elongated motile extensions of cell, Functions: movement of fluid and particles
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* Desmosome junction:
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prevents cells from being pulled apart
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Hyperplasia-
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stimulated mitotic divisions in cells by increased functional demands, (ex: getting callouses from weightlifting)
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Dysplasia-
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deranged cellular growth resulting in variations in size, cells GONE WILD (ex: tumor)
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Metaplasia-
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the transformation of one cell type into another-( ex. an epithelial cell transforming into a fibroblast (which secrets collagen), which aid in healing)
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Pinocytosis
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– small vesicles (cell drinking)
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Phagocytosis –
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very large vesicles (cell eating)
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hyperpolarization
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when membrane potential becomes even more negative than the resting potential
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depolarization
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movement of the membrane potential from resting toward zero
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repolarization
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movement of the membrane potential back to resting
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Hypopolarization
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when the membrane potential becomes less negative or more positive
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Acetylcholine Neurotransmitters
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Cholinergic Neurons
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Amino Acid Neurotransmitters
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Glutamate (stimulatory), Aspartate (stimulatory), GABA (inhibitory), Glycine (mostly inhibitory, but stimulatory when bind to glutamate receptor)
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Amine Neurotransmitters
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Norepinephrine, Epinephrine, Dopamine, Serotonin, Histamine (all derived from amino acids)
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Polypeptide Neurotransmitters
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Substance P, Endorphines and Enkephalins, Cholecystokinin (CKK), Antidiuretic Hormone (ADH)- pleasure neurotransmitters
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Purine Neurotransmitters
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Adenosine monophosphate (AMP), Adenosine triphosphate (ATP)
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Gas Neurotransmitters
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Nitric Oxide (NO) (made from oxygen and arginine-freely diffuses and binds to proteins in cells)
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what types of cell functions do hormones alter?
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* gene transcription, Protein synthesis, enzyme activation
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lipophilic hormone
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a hormone that can go through the membrane and can change cell function directly. It needs a carrier in the blood cause water and lipids don't mix
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lipophobic hormone
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a hormone that binds on a receptor outside the cell. A protein that instigates a second messenger response to do the work and not the actual hormone.. ( ex. cAMP, and IP3, Ca++) A lipophobic hormone is usually a protein
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What second messenger does glucagon cause to be made?
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it causes adenilate cyclase to convert ATP into cAMP. As a second messenger, cAMP can cause enzyme activation, enzyme synthesis, or cell secretion
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What second messenger does epinephrine cause to be activated?
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it causes the release of IP3, which, in turn mobilizes Ca++. As a second messenger, Ca++ causes enzyme activation and cell secretion.
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What contains 40 hydrolyses?
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lysosomes
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Which is smaller, a polypeptide or a protein?
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polypeptide
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What system is not entirely concerned with maintaining homeostasis?
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reproductive system
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What two systems are most concerned with homeostasis?
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nervous and endocrine systems
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What is the driving force of the body's reactions?
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homeostasis
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What is a desmosome junction?
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they anchor cells together because they are made up of filaments that are bound to the membranes,
for strength |
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are steroids lipophilic or phobic?
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philic
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do platelets secrete prostacyclin?
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no
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are antibodies proteins?
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yes
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What doesn't the filtrate pass through?
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podocyte plasma
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Where is the Na/K pump located in tubular cells?
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in the basolateral membrane
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