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51 Cards in this Set

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Macrolides
Quinolones
Tetracyclines
Atypicals - (Mycoplasma, Chlamydia, Legionella)
Atypicals cause respiratory infections
Piperacillin/tazobactam (Zosyn)
S, S, E, H, E, P, B
Amoxicillin/clavulanate - (Augmentin)
Ampicillin/Sulbactam - (Unasyn)
S, S, E, H, E, B
Loses Pseudomonas coverage
Nafcillin, Oxacillin, Methicillin, Dicloxacillin, Cloxacillin
Staph and Strep
Ampicillin & Amoxicillin
Strep and Enterococci
Weak Gram (-)
Penicillin
Strep
Enterococci
What bug does is not covered by cephalosporins?
Enterococci
Cephalexin (Keflex)
Cefazolin (Ancef)
Gram (+) --> Staph, Strep
Weak Gram (-) -->
If you have a patient with a community acquired E. coli UTI and the patient had not received a lot of antibiotic courses previously or been recently admitted to the hosptial, what do you treat with?
1st Gen. Cephalosporin
Cephalexin (Keflex)
Cefazolin (Ancef)
Cefotetan /Cefprozil/ Cefuroxime/Ceftriaxone
S, S, H, E, B
Ceftriaxone (Rocephin)
This should be a 2nd generation as it does not capture any new organisms. S, S, H, E
Ceftazidime (Fortaz)
Lost gram (+) activity, but picked up Pseudomonas. weak gram (+) and H, E, P
cefepime (Maxipime)
Think of ceftriaxone + ceftazidime. S, S, H, E, P
Ceftaroline (Teflaro)
Think of ceftriaxone (rocehpin) + MRSA coverage. S, S, H, E
What are the 4 carbapenems?
Doripenem
Meropenem
Imipenem
Ertapenem
What do the carbapenems cover?
S, S, E, H, E, P, B
Except for Ertapenem, no P
Aztreonam (Azactam)
H, E, P
Cipro
weak gram (+)
H, E, P and atypicals
Moxifloxacin
S, S, E, H, E, B and atypicals
Levofloxacin
S, S, E, H, E, P and atypicals
Clindamycin (Cleocin)
S, S, B and MRSA
Macrolides
Clarithromycin
Azithromycin
S, S, H and atypicals
Septra
S, S (not group A), H, E, MRSA
Tetracyclines
Doxy/Mino/Tetra
S, S, H, MRSA and atypicals
Vancomycin
MRSA and gram (+) w/ pts who have type 1 penicillin allergy
Linezolid
MRSA and VRE
Daptomycin
MRSA and VRE
Tigecycline
MRSA and VRE, also the only gram (+) resistant antibiotic that has good gram (-) activity
Metronidazole
B frag
Nitrofurantoin
S, S, E, Enterics
What are the key side effects for B-lactamase Inhibitors (Augmentin, Unasyn)
Diarrhea, TTP, Hypersensitivity
What are the key side effects for Anti-staph Penicillins
Acute Interstitial Nephritis
What are the key side effects of the extended penicillins
Seizures, anaphylaxis, C. Diff, TTP
What are the key side effects of Cephalosporins
Seizures, hypersensitivity, C. Diff, TTP (1st gen) hemolytic anemia (2nd gen)
What are the key side effects of Carbapenems
Seizures, hypersensitivity, C. Diff, dec. hgb, inc. pt count
What are the key side effects of Quinolones
QT prolongation, C. Diff, Tendonitis/tendon rupture, hypersensitivity
What are the key side effects of aminoglycosides
NM blockers, C. Diff., rash, Oto and nephrotoxicity
What are the key side effects of Macrolides
QT prolongation (rare), Diarrhea - Erythromycin, Metallic taste - Clarithromycin
What are the key side effects of Bactrim/Septra
C. Diff, agranulocytosis, anemia, hyperK, Stevens-Johnson syndrome, rash, Nephrotoxicity, SCr assay issues
What are the key side effects of tetracyclines
C. Diff, photosensitivity, tooth discoloration
What are the key side effects of Aztreonam?
neutropenia, rash
What are the key side effects of Vancomycin
TTP, Red Man Syndrome, nephro and ototoxicity
What are the key side effects of Telavancin
QT Prolongation, Rash, nephrotoxicity, foamy urine
What are the key side effects of Linezolid
myelosupression, rash, lactic acidosis, peripheral neuropathy
What are the key side effects of Synercid
Hepatotoxicity, rash, phlebitis
What are the key side effects of Clindamycin
NM blockade, C. Diff, agranulocytosis, TTP, rash
What are the key side effects of Tigecycline
anaphylaxis, pancreatitis, Severe N/V, anemia TTP, photosensitivity, tooth discoloration
What are the key side effects of Daptomycin
anemia, rash, myopathy, CPK elevation
What are the key side effects of Metroidazole
seizures, encephalopathy (long term tx) rash, disulfram rxn, peripheral neuropathy, metallic taste
What are the key side effects of nitrofurantoin
hepatic impairment, anaphylaxis, rash
What are the key side effects of Rifampin
hepatotoxicity, arthralgias/myalgias, red discoloration of body fluids, nephrotoxicity