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10 Cards in this Set

  • Front
  • Back

Regulation of glycolysis and gluconeogenesis

Regulation of Krebs cycle

Inhibitors of ETC

Amytal = complex I



Antimycin = complex III



CO = Fe2+ in complex IV


Cyanide = Fe3+ in complex IV

Glucose transporters

GLUT1: basal uptake by all cells



GLUT2: basal uptake and export by pancreatic B cells, liver cells, etc



GLUT3: basal uptake by all cells



GLUT4: insulin dependent basal uptake into muscle and fat



GLUT5: fructose uptake in SI

Energy released by breakdown of ATP into ADP/AMP

ADP: -30.5 kJ/mol


AMP: -45.6 kJ/mol

Why does RER lose accuracy during exercise?

Bicarbonate buffering

Regulation of glycogenolysis

Glycogen phosphorylase


(-) ATP, glucose, glu-6-P


(+) Ca2+


FA breakdown (inc. regulation)

TAG breakdown enzymes

ATGL (from perilipin) - HS lipase - MAG lipase


Regulation in fed state

Glycogenesis


Glycogen synthase


(-) glucagon


(-) Ca2+



FA Synthesis


Acyl CoA carboxylase (RLS)


(-) palmitoyl CoA


(+) citrate