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47 Cards in this Set

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  • Back
What is gynecomastia?
If the breast appear enlarged, distinguish between the soft fatty enlargment of obesity and the firm disc of grandular enlargement, called gynecoastia
What are the causes of gynecomastia?
Arises from the imbalance of estrogen and androgens sometimes drug related.
What are the causes of male breast cancer?
Risks are BRCA2 mutations obsity, family hx of male or female breast cancer, testicular disorder, and work exposure to high tempertures and exhaust emission.
What are the significance of findings on palpation of tender cords
Tender cords suggest mammary duct ectasia, a benign but sometimes painful condition of dilated ducts with surrounding inflammtion
What are the significance of findings on palpation of tender nodules?
Tender nodules are hard, irregular, poorly circumscribed nodules, fixed to the skin or underlying tissues, stringly suggests breast cancer.
What are the findings and significance of acanthosis nigrican in the axilla?
Deeply pigmented, velvety axillary skin suggests acanthosis nigricans - one form is associated with internal malignancy.
what are the causes of enlarged axillary lymph nodes?
from infection of the hand or arm, recent immunizations or skin test in the arm, or part of a generalized lymphadenopathy.
What are the features of malignant axillary lymph nodes?
Nodes that are large ( equal to or more 1cm) and firm and hard, matted togeather, or fixed to the skin or to underlying tissues suggest malignant involvment.
What are the 4 groups of lymph nodes in axilla?
?Central nodes, pectoral nodes (anterior), subscapular nodes (posterior), and lateral
Where are their 4 lymph nodes in the axilla locationed?
Central nodes - high in the axillary and midway between the anterior and posterior axillary folds.
Pectoral nodes (anterior), - along the lower border of the pectoralis major inside the anterior axillary fold. Subscapular nodes (posterior)- located along the lateral border of the scapula;palpated deep in the axillary fold.
Lateral - located along the upper humerous.
What are the areas of drainage for all 4 lymph nodes in the axilla
Central nodes;drain channels from three other groups of lymph nodes, which are seldom palable.
Pectoral nodes (anterior); Drains the anterior chest wall and much of the breast.
Subscapular nodes (posterior); They drain the posterior chest wall and a portion of the arm.
Lateral node; They drain most of the arm.
Where do the lymph nodes in the axilla empty their lymph?
pectoral, subscapular, and lateral nodes all drain into the central nodes. Lymph then drains from the central node to the infraclavicular and supraclavicular nodes.
What other lymph nodes the malignant cells from breast may mestastisize?
?Not all the lympathics of the breast drain into the axilla. Malignant cells from a breast cancer may spread directly to the infraclavicular nodes or deep channels within the chest.
Define nonpuerperal galactorrhea?
Milky discharge unrelated to a prior pregnancy
What are the causes of nonpuerperal galactorrhea?
hypothyroidism, pituitary prolactinoma and drugs that are dopamine agonists, including many psychotrophic agents and phenothiazines.
What are the causes of spontaneous unilateral bloody discharge?
evaluate for;
intraductal papilloma
ductal carcinoma in situ
paget's disease of the breast
What are the signs of recurrence of breast cancer after mastectomy?
masses, nodlarity, and change in the color or inflammation, especailly in the incision line, suggest recurence of breast cancer.
How will you instruct a pt for breast self eaxamination.Lying supine
1. Lie down with a pillow under your right shoulder. Place your right arm behind your head.
2. use the finger pads of the three middle fingers on your left hand to feel lumps in the right breast.
3. press firmly enough to know hoe your breasts feels.A firm ridge in the lower curve of each breast is normal. If you're not sure how hard press, talk with your health provider.
4. Press firmly on the breast in an up and down or strip pattern. you can also use a circular or wedge pattern, but be sure to use the same pattern each time. Check entire breast each month.
5. Repeat on left breasts
6. Any masses lumps or skin changes, see you doc!
How will you instruct a pt for breast self eaxamination.Standing
Reapeat the examination of both breast while standing, with one arm behind your head. The upright position makes it easier to check the upper outer part of the breasts( towards the armpit) This is where about half of breast cancer is found, You may want do in shower! soapy hands make it easier to glide over the skin!
2. check breasts in mirror each month- note changes
3. Any masses lumps or skin changes, see you doc
What are the three most common causes of breast nodules?
Fibroadenoma ( benign tumor)
Cysts
Cancer
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Usual age
Fibroadenoma ( benign tumor)- 15-25 usually puberty and young adulthood, but up to age 55
Cysts- 30-50 regress after menopause except with estrogen therapy.
Cancer- 30-90 most common over 50
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Number
Fibroadenoma ( benign tumor)- usually single may be multiple
Cysts - single or multiple
Cancer- usually single, although may coexist with other nodule
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Shape
Fibroadenoma ( benign tumor)- Round, disclike,or lobular
Cysts- Round
Cancer- irregular or stellate
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Consistency
Fibroadenoma ( benign tumor)- may be soft, usually firm
Cysts- soft to firm, usually elastic
Cancer- firm or hard
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Delimitation
Fibroadenoma ( benign tumor)- Well delineated
Cysts- Well delineated
Cancer- Not clearly delineated from surrounding tissue
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Mobility
Fibroadenoma ( benign tumor)- very mobile
Cysts- mobile
Cancer- fixed to the skin or underlying tissues
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Tenderness
Fibroadenoma ( benign tumor)- usually nontender
Cysts- often tender
Cancer- usually non tender
What are the differences between them Fibroadenoma ( benign tumor),Cysts and Cancer in different aspects; Retraction signs
Fibroadenoma ( benign tumor)- Absent
Cysts- Absent
Cancer- may be present
What are the rectraction signs of breast cancer?
As breast cancer advances it causes fibrosis( scar tissue) Shortening of this tissue produces, dimpling changes in contour and retraction deviation of the nipple.
What are the other causes of brest rectraction?
fat necrosis and mammary duct ectasia
What is the Peau d' orange sign in the breast?
Edema of the skin is produced by lymphatic blockage. It appears as thickened skin with enlarged pores. Often seen first in the lower portion of the breast or areola.
What is the visible sign in Paget's disease of the nipple?
Scaly, eczemalike lesion that may weep, crust or erode.
What is the milk line?
This is the area where occasionally one or more extra nipples are located. Only a small nipple and areola are present, often mistaken for a common mole. There is no pathologic significance.
Lymphatic Drainage of the Breast
- mostly drain down towards the axilla
- of the axillary nodes the central nodes are palpable most frequently.
- the pectoral anterior nodes, subscapular posterior nodes and Lateral nodes all drain into the central nodes deep within the axilla, then the lymph drains from the central axillary nodes to the infraclavicular and supraclavicular nodes.
What is galactorrhea?
Galactorrhea is the inappropriate discharge of milk-containing fluid.
It is abnormal if it occurs 6 or more months after childbirth or cessation of breastfeeding.
Name the palpable masses of the breast at different ages
15-25 Fibroadenoma, usually smooth rubbery, round, mobile, non tender.
25-50 Cysts, usually soft to firm, round mobile, often tender.
Fibrocystic changes, Nodular and rope-like.
Cancer Irregular, firm, may be mobile or fixed to surrounding tissue.
Over 50- Cancer until proven otherwise
The relative risk factors for breast cancer and strength of the risks.
Relative risk is > 4.0 for being female, Greater than 65, greater than 45 if you are a Black woman, certain inherited genetic mutations for breast cancer (BRCA1 and or BRCA 2) Two or more 1st degree relatives with breast cancer diagnosed at an early age. personal hx of breast cancer, high breast tissue density, biopsy confirmed atypical hyperplasia.

Relative risk is 2.1-4.0 if you have 1 first degree relative with breast cancer.
Have had high dose radiation to the chest. High bone density (postmenopausal)

Relative risk is 1.1-2.0 late age at first full term pregnancy (>30 years old). Early menarche (<12)Late menopause(>55). No full term pregnancies. Never breastfed. Recent oral contraceptive use. Recent and or long term use of hormone replacement therapy
Obesity postmenopausal

Other factors may include personal history of endometrium, ovary, or colon cancer
Alcohol consumption. height(tall) high socio economic status, Jewish heritage.
What are the risk factors of breast cancer that can be modified?
Modifiable risks include: postmenopausal obesity, use of HRT, alcohol ingestion, physical inactivity, choices about breastfeeding, and type of contraception.
What is the relations of mammographic breast density with causation of breast cancer?
Most undervalued and underused risk factor.
omen with radiologically density is more than 60 to 75% of the breast are 4 to 6 times more at risk of Breast cancer...read more!
What is the recommendations of screening mammography, CBE,and BSE
Mommagraphy- ages 40-50 - every 1 to 2 years
CBE ( clinical breast examination)- 20 -40 every 3 years
BSE( breast self examination)-American cancer society no longer recommends monthly BSE! should be monthly 5 to 7 days after the onset of menses.
What are the 4 views of inspection of the breast.
arms at side.
Arms over head
arms pressed against hips
Leaning forward.
What are the causes of breast redness
from local infection or inflammatory carcinoma.
What are the causes of breast redness thickening and prominent pores in the skin of breasts
Suggest breast cancer
What are the causes of breast flattening of the normal convex?
Suggest breast cancer
What causes dimpling of the breast? What is it's significance?
When a cancer or its associated fibrous strands are attached to both the skin and the fascia overlaying the pectoral muscle, pectoral contraction can draw the skin inwards. Suggest breast cancer-can be a benign lesion- should check!
What is nipple retraction? What is it's significance?
Recent of fixed flattening or depression of the nipple suggests nipple retraction. May be broadened of thickened suggesting an underlying cancer.
What are the different findings on palpation of breasts in breast cancer?
Hard irregular poorly circumscribed nodules, fixed to the skin or underlying tissues, cysts inflamed ares; some cancer can be tender.A mobile mass that becomes fixed when the arm relaxes is attached to the ribs and intercostal muscles; if fixed when the hand is pressed against the hip, it is attached to the pectoral fascia. thickening of the nipple and loss of elasticity suggest underlying breast cancer.