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7 Cards in this Set
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Alkylating agents
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Cell cycle specific
First type of clinically used anticancer agents Alkylate DNA to form covalent cross-links preventing cell replication |
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Nitrogen mustards
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Alkylating agents.
mechlorethamine, chlorambucil, melphalan, bendamustine |
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Alkane sulfonates
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Alkylating agents.
busulfan, treosulfan |
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Aziridines
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Alkylating agents.
thiotepa, triethelyenemelamine (hexamethylmelamine) |
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Oxazaphosphorines
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Alkylating agents.
cyclophosphamide, ifosfamide, trofosfamide |
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Nitrosoureas
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Alkylating agents.
carmustine (BCNU), lomustine (CCNU), nimustine (ACNU), streptozocin, fotemustine, semustine |
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Miscelaneous alkylating agents
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procarbazine, dacarbazine, mitomycin C
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