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24 Cards in this Set
- Front
- Back
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Indirect acting cholinergic drugs |
Neostigmine - prototype anti cholinesterase drug; primarily usenin Myasthenia Gravis
Donepezil - works in CNS to inhibit Acetylcholinesterase; treat Alzheimer's Disease |
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Prototype anti cholinesterase drug; primarily usenin Myasthenia Gravis |
Neostigmine |
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Muscarinic poisoning treatment; prototype |
Atropine |
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Competitive antagonists; all systems except musculo-skeletal |
Muscarinic antagonist |
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Antipasmodic to decrease intestinal cramping in IBS |
Dicyclomine HCL |
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Strongest ,general use |
Atropine |
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Overactive bladder |
Oxybutynin Tolterodine |
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Sedation, motion sickness |
Scopolamine |
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Tiotropium: lungs |
Ipratropium |
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IBS, diarrhea |
Dicyclomine |
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Mechanism: block muscarinic receptors by Acetylcholine Route: PO, eye, injection |
Atropine |
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Vasoconstriction |
Alpha 1 activation |
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Cardiac arrest Heart Failure |
Beta 1 activation |
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Bronchodilator |
Beta 2 activation |
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Increase HR and contractility |
Dopamine |
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Activates alpha-2 receptors in CNS |
Clonidine |
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Suppresses NE synthesis and promotes MAO-mediated destruction Similar to Guanethidine (but fewer CNS |
Reserpine |
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Similar to clonidine, but are taken up in brain and convert alpha2 agonist |
Methyldopa |
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Moderate stimulation |
Eg., Drunk |
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Pause, freeze, and blanky |
Absence seizure |
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Very important in hospitals |
Naloxone |
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For veterinarian only |
Neuroleptanalgesia |
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Inhibit/ induce GABA |
Benzodiazepines |
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Reduce neuronal exitability by inhibiting neutotransmission |
GABA (gamma-Aminobutyric acid) |
