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28 Cards in this Set
- Front
- Back
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Has long acting blocking action at 5HT2 reception Treatment of carcinoid tumor(diarrhea, bronchiconstriction, flushing) |
Phenoxybenzamine |
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Resembles the phenothiazine antihistaminic agent in chemical structure and has potent H1-receptor blocking and 5HT2blocking actions. |
Cyprohepatidine |
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Blocks 5HT1c and 5HT2 receptors and has little or no reported antagonist activity at other 5HT or H1 receptors. Used for carcinoid syndome |
Ketanserin |
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Another 5HT2 antagonist, has little or no alpha blocking action. It has been reported to alter bleeding time and to reduce thromboxane formation, presumably by altering platelet function. |
Ritanserin |
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5HT3 antagonist Prevention of nausea and vomiting associated with surgery and cancer therapy |
Granisetron (Kytril, Sancuso), Ondansetron (Zofran, Nozuka) |
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Specific 5HT2A- and 5HT2C- receptor antagonist |
Clozapine (Clozaril) |
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Antagonist at 5HT2A-, 5HT2C-, an dopamine (D2)- receptors |
Risperidone (Risperdal) |
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Antagonist: Antipsychotic |
Agonist: Antidepressant |
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Antagonist: Hypertension |
Agonist: Migraine |
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Antagonist: Antiemetic |
Agonist: Anxiolytic |
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Antagonist: Carcinoid Tumor |
Agonist: Gastroprokinetic |
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COX 1:ConstitutivePresent in kidneyMaintain healthy gastric juice |
COX 2:InducibleInflammationInhibited by celecoxibPresent in connective tissues COX 2:InducibleInflammationInhibited by celecoxibPresent in connective tissues |
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Dinoprostone (PGE3)Administered vaginally for useAbortion Dinoprostone (PGE3)Administered vaginally for useAbortionCervical retinin Cervical retinin |
Oxytocic |
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Carboprost Tromethamine (15- methyl-PGF2a) Intra-amniotic injection2nd trimester abortion |
Abortion |
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PGE2 , PGF2a |
Facilitation of Labor |
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PGI1 peripheral pulmonary and coronary resistance Prostacyclin (PGI2, Epoprostenol)Iloprost Treprostinil |
Pulmonary Hypertension |
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PGE and PGI2 |
Peripheral Vascular Disease |
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Alprostadil (PGE1) |
Patent Ductus Arteriosus |
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Propionic acid derivative |
Ibuprofen |
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Tolmetin |
Pyrrolealkanoic acid derivative |
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Flubiprofen |
Phenylalkanoic acid derivative |
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Indomethacin |
Indole derivative |
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Diclofenac |
Phenylacetic acid derivative |
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Pyrazolone derivative |
Phenylbutazone |
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Meclofenamate acid |
Fenamate |
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Piroxicam |
Oxicam |
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Naphthylacetic acid prodrug |
Nabumetone |
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Kinins Vasoactive Intestinal Peptides (VIP) Substance P-Neurotransmitter and as a neuromodulator belongs to the tachykinin |
IcabitantNeurokinin receptor antagonistAprepitant |
