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73 Cards in this Set

  • Front
  • Back
How would you discontinue a benzo?
Taper daily dose down by 1/4 Q 14 days

after 14 days, reduce the morning fose, then HS dose.
This Benzo available sublingually
Ativan (Lorazepam)
Ativan

generic
dose
Lorazepam
0.5, 1, 2

Sublingual, injection
This intermediate acting Benzo can be used for sleep
Restoril (Temazepam)
Xanax (Alprazolam)
Klonopin (Clonazepam)
Restoril

Generic
dose
(Temazepam)
7.5, 15, 22.5, 30mg
This intermediate acting Benzo requires low gastric pH
Tranxene (Clorazepate)
Tranxene

Generic
Dose
(Clorazepate)
3.75, 7.5, 15mg
This benzo is used IV for epilepsy
Valium (Diazepam)

lipid soluble
T/F Valium lacks an active metabolite
FALSE
Valium

Generic
dose
Diazepam
2,5,10mg
Soln: 5/5ml
Xanax

Generic
Dose
Alprazolam
0.25, 0.5, 1, 2
XR: 0.5, 1, 2, 3
This Benzo is fast acting and has a short duration
Halcion (Triazolam)
Halcion

Generic
Dose
Triazolam

0.125, 0.25
this benzo is HIGHLY lipid soluble
Klonopin (clonazepam)
Klonapin

Generic
dose
Clonazepam
0.5, 1, 2

wafers: 0.125, 0.25, 0.5, 1, 2
Ambien

Generic
Dose
MOA
Zolpidem
5,10mg
CR:6.25, 12.5mg

Bind to GABA omega-1 receptor (more specific for sleep)
What is the difference between Ambien and Sonata?
Sonata has a shorter onset and duration
Sonata

generic
dose
MOA
Zalepion

5,10mg

Binds to GABA omega-1 receptor specific for sleep
Lunesta

Generic
dose
MOA
Eszopidem

1,2,3mg

Binds to GABA omega-1 receptor specific for sleep

Active isomer of Ambien
BuSpar

Generic
Dose
MOA
Buspirone
5,10mg also 15,30mg in divided dose

5HT1A partial agonist, normalizes 5HT
T/F ALL TCA's produce anticholinergic effects
TRUE
Elavil

Generic
Dose
Class
MOA
Amitriptyline
10,25,50,75, 100, 150

TCA

bind and block the transporters that re-uptake NE and 5HT
This increases neurotransmitters in the cleft
Norpramin

Generic
Dose
Class
MOA
Desipramine
10,25,50,75,100,150

TCA
Blocks reuptake of NE
These TCAs produce less Anti-cholinergic effects than the others
Norpamin (Desipramine)
Pamelor (Nortriptyline)
Pamelor

Generic
Dose
Class
MOA
Nortriptyline

10, 25, 50, 75

TCA

Blocks the transporters that re-uptake NE and 5HT
This TCA is available in an injection
Elavil (Amitriptyline)
This TCA is available as an oral solution
Pamelor (Nortriptyline)
Anafranil

Generic
Dose
Class
MOA
Clomipramine
25,50,75mg

TCA
5HT reuptake inhibitor
This TCA is indicated for OCD
Anafranil (Clomipramine)
This TCA should be taken with food to reduce GI SE
Anafranil (Clomipramine)
This is an activating SSRI and should be taken in the AM
Prozac (Fluoxetine)
This is a ADR for all SSRIs
Sexual Dysfunction
What is the Boxed warning for antidepressants?
suicide
This SSRI has a long acting active metabolite
Prozac (Fluoxetine)
Prozac

Generic
dose
Fluoxetine

10,20,40mg

sol 20mg/5ml

Weekly 90 mg caps
Zoloft

Generic
Dose
Class
Sertraline
25,50,100
sol: 20mg/ml

SSRI
This is the shortest acting SSRI
Paxil (Paroxetine)
This SSRI should be avoided in Alzheimers patients
Paxil (Paroxetine)
This SSRI has the most anticholinergic effects
Paxil (Paroxetine)
Paxil

Generic
Dose
Class
Paroxetine
10,20,30,40
susp: 10mg/5ml
CR: 12.5, 25, 37.5

SSRI
This SSRI has less CYP450 interaction than the others
Celexa (Citalopram)
Celexa

Generic
dose
class
Citalopram

10,20,40,
sol. 10mg/5ml

SSRI
This is an isomer of citalopram
Lexapro
Lexapro

Generic
dose
class
Escitalopram
5,10, 20mg
soln 5mg/5ml
This antidepressent causes a potential for priapism in male patients
Desyrel (Trazodone)
Desyrel

Generic
Dose
MOA
Trazadone
50,100,150,300

Mild SSRI Action
This antidepressant causes Hepatotoxicity
Nefazodone
Remeron

Generic
Dose
Class
MOA
SE
Mirtazapine
15,30,45

Alpha-2-agonist
increases NE
SE: Drowsiness, Orthostasis
Effexor

Generic
dose
MOA
Venlafaxine
25,37.5,50,75,100mg
XR: 37.5 75,150mg

similar action as TCAs
Pristiq

Generic
Class
Desvenlafaxine
50,100mg

similar to Effexor (TCA like)
Cymbalta

Generic
Dose
Class
Duloxetine
20,30,60mg
SNRI
T/F Typical blocks DA > 5HT2
TRUE
Mellaril

generic
Dose
Alternative agent
Thioridazine
10,15,25,50,100,150,200

Thorazine (Chlorpromazine)
Prolonged QTc interval is a boxed warning associated with which drug?
Mellaril (Thioridazine)
This Typical antipsychotic produces more anti-Ach than the others
Mellaril (Thioridazine)
What is the max dose of mellaril (thioridazine)

what may happen if that dose is exceeded?
800mg/day

eye problems
Haldol

Generic
Dose
Alternative
Haldol (Haloperidol)

0.5, 1, 2, 5, 10, 20mg
Prolixin
This class of psychotropics has a boxed waring for elderly patients with dementia-related psychosis: increased risk of death: CV or infection
Atypical Antipsychotics
What is the class AE of atypical antipsychotics?
Weight gain
potential for DM
Risperdal

Generic
dose
Risperidone
0.25, 0.5, 1, 2, 3, 4mg
These atypical Antipsychotics can be given once a day
Risperdal (Risperidone)
Invega (Paliperidone)
This is the active metabolite of Risperidone

Alternative drug
Invega (Paliperidone)
Invega

generic
dose
Class
Paliperidone
ER:3,6,9
Atypical Antipsychotic
This Antipsychotic requires a dose reduction in renal impairment
Invega (Paliperidone)
Zyprexa

Generic
Dose
Class
Alternative
Olanzapine
2.5, 5, 7.5, 10, 15, 20mg
Dis: 5, 10, 15, 20
Clozapine
This atypical antipsychotic is indicated for the treatment of depressive episodes associated with bipolar disorder and also treatment resistant depression
Symbyax (Olanzapine-fluoxetine)
Symbyax

Generic
Dose
class
Olanzapine-fluoxetine
3/25, 6/25, 12/25, 12/50mg
Atypical Antipsychotics
what is contraindicated with Symbyax?
during or within 14 days of MAOIs
This antipsychotic has the lowest EPS in the class
Seroquel (Quetiapine)
This is the first line treatment for schizophrenia
Seroquel (Quetiapine)
Seroquel

Generic
dose
Class
Quetiapine
25,50,100,200,300,400mg
XR: 50,150,200,300,400

Atypical Antipsychotics
Geodon
dose
Class
(Ziprasidone)
20,40,60,80

Atypical
This has less weight gain than other atypicals
Geodon (Ziprasidone)