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73 Cards in this Set
- Front
- Back
How would you discontinue a benzo?
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Taper daily dose down by 1/4 Q 14 days
after 14 days, reduce the morning fose, then HS dose. |
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This Benzo available sublingually
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Ativan (Lorazepam)
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Ativan
generic dose |
Lorazepam
0.5, 1, 2 Sublingual, injection |
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This intermediate acting Benzo can be used for sleep
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Restoril (Temazepam)
Xanax (Alprazolam) Klonopin (Clonazepam) |
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Restoril
Generic dose |
(Temazepam)
7.5, 15, 22.5, 30mg |
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This intermediate acting Benzo requires low gastric pH
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Tranxene (Clorazepate)
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Tranxene
Generic Dose |
(Clorazepate)
3.75, 7.5, 15mg |
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This benzo is used IV for epilepsy
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Valium (Diazepam)
lipid soluble |
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T/F Valium lacks an active metabolite
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FALSE
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Valium
Generic dose |
Diazepam
2,5,10mg Soln: 5/5ml |
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Xanax
Generic Dose |
Alprazolam
0.25, 0.5, 1, 2 XR: 0.5, 1, 2, 3 |
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This Benzo is fast acting and has a short duration
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Halcion (Triazolam)
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Halcion
Generic Dose |
Triazolam
0.125, 0.25 |
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this benzo is HIGHLY lipid soluble
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Klonopin (clonazepam)
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Klonapin
Generic dose |
Clonazepam
0.5, 1, 2 wafers: 0.125, 0.25, 0.5, 1, 2 |
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Ambien
Generic Dose MOA |
Zolpidem
5,10mg CR:6.25, 12.5mg Bind to GABA omega-1 receptor (more specific for sleep) |
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What is the difference between Ambien and Sonata?
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Sonata has a shorter onset and duration
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Sonata
generic dose MOA |
Zalepion
5,10mg Binds to GABA omega-1 receptor specific for sleep |
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Lunesta
Generic dose MOA |
Eszopidem
1,2,3mg Binds to GABA omega-1 receptor specific for sleep Active isomer of Ambien |
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BuSpar
Generic Dose MOA |
Buspirone
5,10mg also 15,30mg in divided dose 5HT1A partial agonist, normalizes 5HT |
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T/F ALL TCA's produce anticholinergic effects
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TRUE
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Elavil
Generic Dose Class MOA |
Amitriptyline
10,25,50,75, 100, 150 TCA bind and block the transporters that re-uptake NE and 5HT This increases neurotransmitters in the cleft |
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Norpramin
Generic Dose Class MOA |
Desipramine
10,25,50,75,100,150 TCA Blocks reuptake of NE |
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These TCAs produce less Anti-cholinergic effects than the others
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Norpamin (Desipramine)
Pamelor (Nortriptyline) |
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Pamelor
Generic Dose Class MOA |
Nortriptyline
10, 25, 50, 75 TCA Blocks the transporters that re-uptake NE and 5HT |
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This TCA is available in an injection
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Elavil (Amitriptyline)
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This TCA is available as an oral solution
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Pamelor (Nortriptyline)
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Anafranil
Generic Dose Class MOA |
Clomipramine
25,50,75mg TCA 5HT reuptake inhibitor |
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This TCA is indicated for OCD
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Anafranil (Clomipramine)
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This TCA should be taken with food to reduce GI SE
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Anafranil (Clomipramine)
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This is an activating SSRI and should be taken in the AM
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Prozac (Fluoxetine)
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This is a ADR for all SSRIs
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Sexual Dysfunction
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What is the Boxed warning for antidepressants?
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suicide
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This SSRI has a long acting active metabolite
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Prozac (Fluoxetine)
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Prozac
Generic dose |
Fluoxetine
10,20,40mg sol 20mg/5ml Weekly 90 mg caps |
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Zoloft
Generic Dose Class |
Sertraline
25,50,100 sol: 20mg/ml SSRI |
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This is the shortest acting SSRI
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Paxil (Paroxetine)
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This SSRI should be avoided in Alzheimers patients
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Paxil (Paroxetine)
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This SSRI has the most anticholinergic effects
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Paxil (Paroxetine)
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Paxil
Generic Dose Class |
Paroxetine
10,20,30,40 susp: 10mg/5ml CR: 12.5, 25, 37.5 SSRI |
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This SSRI has less CYP450 interaction than the others
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Celexa (Citalopram)
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Celexa
Generic dose class |
Citalopram
10,20,40, sol. 10mg/5ml SSRI |
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This is an isomer of citalopram
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Lexapro
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Lexapro
Generic dose class |
Escitalopram
5,10, 20mg soln 5mg/5ml |
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This antidepressent causes a potential for priapism in male patients
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Desyrel (Trazodone)
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Desyrel
Generic Dose MOA |
Trazadone
50,100,150,300 Mild SSRI Action |
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This antidepressant causes Hepatotoxicity
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Nefazodone
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Remeron
Generic Dose Class MOA SE |
Mirtazapine
15,30,45 Alpha-2-agonist increases NE SE: Drowsiness, Orthostasis |
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Effexor
Generic dose MOA |
Venlafaxine
25,37.5,50,75,100mg XR: 37.5 75,150mg similar action as TCAs |
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Pristiq
Generic Class |
Desvenlafaxine
50,100mg similar to Effexor (TCA like) |
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Cymbalta
Generic Dose Class |
Duloxetine
20,30,60mg SNRI |
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T/F Typical blocks DA > 5HT2
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TRUE
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Mellaril
generic Dose Alternative agent |
Thioridazine
10,15,25,50,100,150,200 Thorazine (Chlorpromazine) |
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Prolonged QTc interval is a boxed warning associated with which drug?
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Mellaril (Thioridazine)
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This Typical antipsychotic produces more anti-Ach than the others
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Mellaril (Thioridazine)
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What is the max dose of mellaril (thioridazine)
what may happen if that dose is exceeded? |
800mg/day
eye problems |
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Haldol
Generic Dose Alternative |
Haldol (Haloperidol)
0.5, 1, 2, 5, 10, 20mg Prolixin |
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This class of psychotropics has a boxed waring for elderly patients with dementia-related psychosis: increased risk of death: CV or infection
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Atypical Antipsychotics
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What is the class AE of atypical antipsychotics?
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Weight gain
potential for DM |
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Risperdal
Generic dose |
Risperidone
0.25, 0.5, 1, 2, 3, 4mg |
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These atypical Antipsychotics can be given once a day
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Risperdal (Risperidone)
Invega (Paliperidone) |
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This is the active metabolite of Risperidone
Alternative drug |
Invega (Paliperidone)
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Invega
generic dose Class |
Paliperidone
ER:3,6,9 Atypical Antipsychotic |
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This Antipsychotic requires a dose reduction in renal impairment
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Invega (Paliperidone)
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Zyprexa
Generic Dose Class Alternative |
Olanzapine
2.5, 5, 7.5, 10, 15, 20mg Dis: 5, 10, 15, 20 Clozapine |
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This atypical antipsychotic is indicated for the treatment of depressive episodes associated with bipolar disorder and also treatment resistant depression
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Symbyax (Olanzapine-fluoxetine)
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Symbyax
Generic Dose class |
Olanzapine-fluoxetine
3/25, 6/25, 12/25, 12/50mg Atypical Antipsychotics |
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what is contraindicated with Symbyax?
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during or within 14 days of MAOIs
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This antipsychotic has the lowest EPS in the class
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Seroquel (Quetiapine)
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This is the first line treatment for schizophrenia
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Seroquel (Quetiapine)
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Seroquel
Generic dose Class |
Quetiapine
25,50,100,200,300,400mg XR: 50,150,200,300,400 Atypical Antipsychotics |
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Geodon
dose Class |
(Ziprasidone)
20,40,60,80 Atypical |
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This has less weight gain than other atypicals
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Geodon (Ziprasidone)
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