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77 Cards in this Set

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This CV drug also relaxes esophageal spasms and has been used to treat peripheral vascular problems
Procardia

Adalat CC

(NIFEDIPINE)
Name a SE a patient might get from Procardia (Nifedipine)
Gum Hyperplasia
Dynacirc

Generic
Class
Dose
isradipine
DHP CCB
2.5, 5mg
CR: 5, 10mg
Sular

Generic
Class
Dose
Nisoldipine
DHP CCB
ONCE A DAY (Various mg)
Norvasc

Generic
Class
Dose
Amlodipine
DHP CCB
2.5, 5, 10mg
ONCE A DAY
Name 2 DHP CCBs that are NOT taken once daily
Procardia
Cardene
Cardene

Generic
Class
Dose
Dosing
Nicardipine
DHP CCB
20, 30mg
30,45,60mg
TID-BID
Caduet
Generic
Class
Dose
Amlodipine/atorvastatin
DHP CCB/ statin
2.5/10,20,40
5/...
10/...
Lotrel

generic
dose
Amplodipine/benazepril
2.5/10, 5/10, 20
10/20mg
Usually CCBs arent recommended for arrhythmias with the expecption of which drug?
Cardizem (Diltiazem)
These CCBs may cause Constipation
Verapamil Diltiazem
Digoxin taken with which CCB may increase Dig toxicity
Verapamil
Name some brand names for Diltiazem
Cardizem
Dilt CD
Tiazac
Taztia XT
Dilacor XR
DILTXR
Diltia XR
Cartia XR
Name some brand names for Verapemil
Calan
Isoptin SR
Verelan
Verelan PM
Covera HS
Which disease states would you use Calan and which would you use Calan SR?
Calan: angina, arrhythmias, HTN

Calan SR: HTN
This Verapamil is taken at bedtime
Covera HS
T/F tale Isoptin SR and other SR NON-DHP CCBs with food
TRUE
What is the MOA of ACE-I
blocks conversion of ATI-->ATII which DECREASED Aldosterone

Enhances Vasodilation by increasing Bradykinin levels (ACE breaks dwn BK: ACE-I inc levels)
What antihypertensive medications would you recommend for a patient on her 2nd trimester of pregnancy?
Aldomet (Methyldopa)
Apresoline (hydralazine)
ACE-I are __ sparing
Potassium

WATCH SALT SUBSTITUTES
SE of ACE-I
Angioedema, Cough
Capoten

Generic
Dose
Captopril
*12.5, 25, 50, 100*
Vasotec

Generic
Dose
Enalapril *2.5*, 5, 10, 20
Enalaprilat-Injection *1.25*
Altace

Generic
Dose
Ramipril

*1.25, 2.5, 5, 10*
This ACE-I is for patients who cannot swallow... caps may be opened and taken w applesauce
ALTACE (ramipril)
This ACE-I is eliminated 50% in urine and feces

ADVANTAGE in renally impared
Monopril
(forinpril)
Prinivil, Zestril

Generic
Dose
Lisinopril

*2.5*, 5, 10, 20, *30*,40mg
Lotensin

Generic
Dose
Benazepril
5, 10, 20, 40
Accupril
quinapril
5, 10, 20, 40
Aceon

Generic
Dose
perindopril
2, 4, 8mg
Mavik

Generic
Dose
trandolapril
1, 2, 4mg
Univasc

Generic
Dose
moexipril
7.5, 15mg
Tarka

Generic
Tandolapril w/ Verapamil
New Product: Direct Renin Inhibitor
Tekturna
MOA of ARBs
Block ATII at type AT1 receptors
Cozaar

Generic
dose
Lostartan

25, 50, 100mg
Diovan

Generic
Dose
Valsartan

40, 80, 160, 320mg
Avapro

Generic
Dose
irbesartan

75, 150, 300mg
**Atacand**

Generic
Dose
Candesartan
**4, 8, 16, 32**
Benicar

Generic
Dose
Olmesartan
5, 20, 40
**Teveten**

Generic
Dose
Eprosartan
400,600mg
Micardis

Generic
Dose
Telmisartan
20,40,80mg
This drug is an alpha-2 agonist (AUTORECEPTOR AGONIST) and cholinergic agonist.. also decreases NE
Catapres
Catapres TTS 1, 2, 3 patches
SE of Catapres
Dry Mouth Constipation
(Anti-Ach SE)
These alpha-1 agonists can also be used for BPH.
Hytrin (Terazosin)
Cardura (Doxazosin)
Counselling points for Hytrin (terazosin) and Cardura (Doxazosin)
first dose: take at 8pm bc of syncope

caution OTC meds like Sudafed, anticholinergics, Benadryl)
This alpha 1 agonist is taken BID or TID
Minipress
(prazosin)
This antihypertensive is an ARTERIOLAR vasodilator
Apresoline
(Hydralazine)
Name 2 fibrate derivative Lipid lowering agents and state their MOA
Lopid (gemfibrozil)
Tricor (fenofibrate) Antara Lofibra

Lower TG and LDL by activating Lipoprotein Lipase
Which Lipid Lowering agent must you be cautious of Rhabdomyolysis?
Lopid (Gemfibrozil)
Statins
Large amts of Tricor
T/F it is recommended you take Lopid w food
False... better absorption 30 min before meals

GI Upset is a common SE
Which Statin has NO CYP450 Interactions?
Pracachol (pravastatin)
statin Dose Equivalencies:
Rosuvastatin 5mg
Atrovastatin 10mg
Simvastatin 20mg
Lovastatin 40mg
Pravastatin 40mg
Fluvastatin 80mg

Rose And Sam Love Pringles w Flavor
which statin is it recommended to take on HS?
Altoprev ER (lovastatin)
Crestor
Rosuvastatin
5,10,20,40
Lipitor
Atrovastatin
10,20,40,80mg
Zocor
Simvastatin
5, 10, 20, 40, 80
Mevacor
Lovastatin
10, 20, 40
20, 40, 60mg (Altoprev)
Pravachol
pravastatin
10, 20, 40, 80
Lescol
Lescol XL
fluvastatin
20, 40
80mg
Simcor
Niacin w Simvastatin
Common SE is flushing..

... take HS after a low-fat snack

ER minimizes flushing
Niaspan
(niacin)

500,750,1000mg
Advicor
Lovastatin/Niacin
This Lipid lowering agent inhibits absorption of cholesterol but has a very small effect on reduction of LDL
Zetia ezetimibe
Vytorin
ezetimibe/simvastatin
Questran

Generic
Dose
MOA
Counselling points
cholestyramine

4g resin/9g powder= 1 dose

Bile acide Sequestrant (Binder)
drink 2nd glass of water to prevent constipation

Binds to drugs so take other meds 2 hrs before or 4-6hrs after taking Questran
Antuarrythmics Classes

I
II
III
IV
I- Na+ channel blockers

II- Beta Blocker (Inderal, Sotalol, Metoprolol)

III- Amiodarone and Sotalol (Cor-da-rone)

IV- CCB (Verapamil
DI w Quinidine
Tonic Water
Digoxin
Quinidex
vs
Quinaglute
Quinidine Sulfate
vs
Quinidine Gluconate
Tambocor

Generic
MOA
Dose
flecainide
Blocks Na+ channels
50, 100, 150mg Q12H!
Rythmol
Propafenone

dose decreased or intervals increased for HEPATICALLY impaired
This anti-arrythmic is on the Beers List
Cordarone
(amiodarone)
Cordarone

Generic
Use
SE
Dose
DI
use: VENTRICULAR arrythmias

SE: Thyroid, smurf syndrome

Dose: 200mg LONG HALF LIFE! 8 mo to SS

DI: Warfarin, Difoxin, CYP3A4 substrate
Betapace

Generic
Class
Dose
Sotalol

Non-Selective BB
Class III anti-arrhythmic

80, 120, 160, 240
you must not administer this antiarrhythmic w/i 2 hrs of AL or MG containing acids
Betapace AF (Sotalol)
This is indicated for A-Flutter
Betapace AF

NOT ideal for COPD patients
T/F Non-DHP CCBs have more vasodilation so a patient may feel dizzy or have swollen ankles
FALSE!!

DHP MORE VASODILATION