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56 Cards in this Set
- Front
- Back
Name Generic, Dose and Indication
Zyloprim |
Allopurinol
100-300mg QD Gout |
|
These 2 drugs inhibit Xanthene Oxidase (which causes production of uric acid) for patients with gout
|
Zyloprim (Allopurinol)
Uloric (Febuxostat) |
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what must you do in a patient who is on Zyloprim (Allopurinol) and Imuran or Purinethol?
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Decrease the dose of Purinethol to 1/3 to 1/4 the original dose
|
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What is good dietary counselling advice for a patient with gout?
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No Lobster, shellfish, clams, wine or organ meats
commonly provokes a gout attack |
|
Name Generic, Dose, and Indication
Uloric |
Febuxostat
40-80mg QD Gout |
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Drug interaction with Uloric (febuxostat)
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Imuran/6-MP
|
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Name Generic, Dose, and Indication
Benemid and ColBenemid |
Probenecid and ColProbenecid
Probenecid 500mg BID ColProbenecid 500mg probenecid + colchicine 0.5mg/tab BID |
|
This is an organic acid.
It inhibits resorption of uric acid in the proximal renal tubules |
Benemid, ColBenemid
|
|
_______ are contraindicated when a patient is taking Probenecid.
Why? |
Salicylates
because they are also organic acids and compete for the same site |
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IF a patient is on Probenecid and Aspirin 81mg, should you d/c the Aspirin?
|
NO- not clinically significant
|
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Bisphosphonates inhibit _________________
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Osteoclasts
|
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Name Generic, Dose, and Indication
Fosomax |
Alendronate
5, 10, 40mg once weekly 35, 70mg ORAL 75ML contains 70MG (ONCE WEEKLY) Osteoporosis |
|
what is in Fosomax Plus D?
|
70mg Fosomax plus 2,800 or 5,600 units of Vitamin D
|
|
Counselling Instuctions for Fosomax (Alendronate)
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Take 30 min before breakfast on empty stomack (no juice, coffee, milk, food)
take with plenty of water and sit up straight for 30 minutes |
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what is a major problem with Fosamax (Alendronate)?
|
Esophageal irritation
|
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when would you give Higher Doses of Fosamoa?
|
Pagets disease
|
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Fosamax dosage for treatment and Prevention
|
70mg one a week for treatment
35mg once a week for Prevention |
|
Name Generic, Dosage, and Indication
Actonel |
Bisphosphonate
Regular: 5, 30mg Once a week 35mg once a month: 150mg Osteoporosis |
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Actonel with Calcium Dosage
|
35 mg tab once weekly on an empty stomach and Calcium Carbonate 1250mg(500mg elemental Ca++) daily for the next 6 days with food to increase absorption
|
|
Name Generic, Dose, Indication
Boniva |
Ibandronate
2.5mg/day 150mg tablet once a month Osteoporisis |
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This is a Hormone that decreases Bone resorption
|
Miacalcin and fortical
(calcitonin Salmon) |
|
This is a nasal spray for Osteoporosis
|
Miacalcin and Fortical
(Calcitonin Salmon) |
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This is a selective Estrogen Receptor Modulator (SERM)
|
Evista (Raloxifene
|
|
Name Generic, Dose, Indication
Evista |
Raloxifene
60mg QD Osteoporosis |
|
Adverse Effects include peripheral edema and hot flashes
|
Evista (Raloxifene)
|
|
This drug Selectively binds certain estrogen receptors, inhibits bone resorption and lowers LDL
|
Evista (Raloxifene)
|
|
This has a black box warning for increased risk of venous thromboembolism and death from stroke
|
Evista (Raloxifene)
|
|
what is the dosage equivalence of synthroid to TH?
|
0.05-0.1mg equals the potency of about 60mg of TH
|
|
This is indicated in Hypothyroidism (elevated TSH)
|
synthroid (Levothroid, Levoxyl)
|
|
Drug Interaction with Synthroid
Patient Counselling |
Al, Fe, Antacids
Take on an empty stomach |
|
Two AntiThyroid Drugs
|
Propylthiouracil (PTU)
Methimazole (Tapazole) |
|
This inhibits the preipheral conversion of T4 to T3
|
PTU
|
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These inhibit the synthesis of Thyroid Hormones
|
PTU, Methimazole
|
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Which Antithyroid is preferred in pregnancy
|
PTU preferred because doesnt cross placenta as easily as methimazole
both Preg cat D |
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Drug Interaction with PTU
|
Oral Anticoagulants
|
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This is indicated for Dyspareunia (painful intercourse)
|
Premarin
|
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What is in the prempro Combination
|
Premarin and Progestin
|
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What estrogen vaginal cream can be substituted for Permarin?
|
Estrace
|
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Name Generic, Dose and Indication
Pletal |
Cilostazol
50,100mg BID Platelet Aggregation Inhibitor |
|
this inhibits PDEIII.This supresses cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, leading to vasodilation and inhibition of platelet aggregation
|
Pletal (Cilostazol)
|
|
this has a BBW- Contraindicated in patients with CHF
|
Pletal (Cilostazol)
|
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Interaction with ______ in Pletal (Cilostazol)
|
CYP450 Inhibitors
|
|
Alternative for Pletal (Cilostazol)
|
Trental (Pentoxifylline)
|
|
Name Generic, Dose, and MOA
Plavix |
Clopidogrel
75mg selectively inhibits the binding of ADP to its platelet receptor and activation of the glycoprotein GPIIb/IIIa complex thereby inhibiting platelet aggregation |
|
Decrease plavix __ days prior to surgery
|
5
|
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Alternative for Plavix
|
Ticlid (Ticlopidine)
|
|
this is a belladonna alkaloid. It inhibits ACh in the vestibular apparatus and input to the CNS
|
Scopolamine
|
|
this is effective in Motion Sickness
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Transderm Scop (Scopolamine)
|
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how do you use Transderm SCop
|
apply one patch behind the ear about 4 hours before the effect is required. Leave on for 3 days
|
|
an off label use is for terminally ill patients to dry Bronchial secretions. What is an alternative for this purpose?
|
Atropine Sulfate 1% opthalmic solution
|
|
Name generic, dose, MOA
Antivert |
Meclizine
12.5m 25, 50mg Antihistamine with some anticholinergic action |
|
Interaction with Colase, Surfak (Docusate Sodium and Calcium)
|
mineral oil'
|
|
Name generic. Dose, MOA
Colase |
Docusate Sodium
50, 100mg cap syrup 60mg/15ml liquid 150mg/15ml facilitates admixture of fat and water to soften stool |
|
Name Generic Dose, MOA
Enulose |
Lactulose
10g/15ml metabolized by colonic bacteris in colon to mild acids. Increased osmolarity causes osmotic evacuation |
|
This binds water and causes water to be retained within the stool
|
MiraLax
|
|
Miralax Generic
|
PEG 3350
|