Pcm Chapter 3 Geriatrics

Front 1

Name Generic, Dose and Indication

Zyloprim

Back 1

Allopurinol

100-300mg QD

Gout

Front 2

These 2 drugs inhibit Xanthene Oxidase (which causes production of uric acid) for patients with gout

Back 2

Zyloprim (Allopurinol)

Uloric (Febuxostat)

Front 3

what must you do in a patient who is on Zyloprim (Allopurinol) and Imuran or Purinethol?

Back 3

Decrease the dose of Purinethol to 1/3 to 1/4 the original dose

Front 4

What is good dietary counselling advice for a patient with gout?

Back 4

No Lobster, shellfish, clams, wine or organ meats

commonly provokes a gout attack

Front 5

Name Generic, Dose, and Indication

Uloric

Back 5

Febuxostat

40-80mg QD

Gout

Front 6

Drug interaction with Uloric (febuxostat)

Back 6

Imuran/6-MP

Front 7

Name Generic, Dose, and Indication

Benemid and ColBenemid

Back 7

Probenecid and ColProbenecid

Probenecid 500mg BID

ColProbenecid 500mg probenecid + colchicine 0.5mg/tab BID

Front 8

This is an organic acid.

It inhibits resorption of uric acid in the proximal renal tubules

Back 8

Benemid, ColBenemid

Front 9

_______ are contraindicated when a patient is taking Probenecid.

Why?

Back 9

Salicylates

because they are also organic acids and compete for the same site

Front 10

IF a patient is on Probenecid and Aspirin 81mg, should you d/c the Aspirin?

Back 10

NO- not clinically significant

Front 11

Bisphosphonates inhibit _________________

Back 11

Osteoclasts

Front 12

Name Generic, Dose, and Indication

Fosomax

Back 12

Alendronate

5, 10, 40mg
once weekly 35, 70mg
ORAL 75ML contains 70MG (ONCE WEEKLY)

Osteoporosis

Front 13

what is in Fosomax Plus D?

Back 13

70mg Fosomax plus 2,800 or 5,600 units of Vitamin D

Front 14

Counselling Instuctions for Fosomax (Alendronate)

Back 14

Take 30 min before breakfast on empty stomack (no juice, coffee, milk, food)

take with plenty of water and sit up straight for 30 minutes

Front 15

what is a major problem with Fosamax (Alendronate)?

Back 15

Esophageal irritation

Front 16

when would you give Higher Doses of Fosamoa?

Back 16

Pagets disease

Front 17

Fosamax dosage for treatment and Prevention

Back 17

70mg one a week for treatment
35mg once a week for Prevention

Front 18

Name Generic, Dosage, and Indication

Actonel

Back 18

Bisphosphonate

Regular: 5, 30mg
Once a week 35mg
once a month: 150mg

Osteoporosis

Front 19

Actonel with Calcium Dosage

Back 19

35 mg tab once weekly on an empty stomach and Calcium Carbonate 1250mg(500mg elemental Ca++) daily for the next 6 days with food to increase absorption

Front 20

Name Generic, Dose, Indication

Boniva

Back 20

Ibandronate

2.5mg/day 150mg tablet once a month

Osteoporisis

Front 21

This is a Hormone that decreases Bone resorption

Back 21

Miacalcin and fortical
(calcitonin Salmon)

Front 22

This is a nasal spray for Osteoporosis

Back 22

Miacalcin and Fortical
(Calcitonin Salmon)

Front 23

This is a selective Estrogen Receptor Modulator (SERM)

Back 23

Evista (Raloxifene

Front 24

Name Generic, Dose, Indication

Evista

Back 24

Raloxifene

60mg QD

Osteoporosis

Front 25

Adverse Effects include peripheral edema and hot flashes

Back 25

Evista (Raloxifene)

Front 26

This drug Selectively binds certain estrogen receptors, inhibits bone resorption and lowers LDL

Back 26

Evista (Raloxifene)

Front 27

This has a black box warning for increased risk of venous thromboembolism and death from stroke

Back 27

Evista (Raloxifene)

Front 28

what is the dosage equivalence of synthroid to TH?

Back 28

0.05-0.1mg equals the potency of about 60mg of TH

Front 29

This is indicated in Hypothyroidism (elevated TSH)

Back 29

synthroid (Levothroid, Levoxyl)

Front 30

Drug Interaction with Synthroid

Patient Counselling

Back 30

Al, Fe, Antacids

Take on an empty stomach

Front 31

Two AntiThyroid Drugs

Back 31

Propylthiouracil (PTU)

Methimazole (Tapazole)

Front 32

This inhibits the preipheral conversion of T4 to T3

Back 32

PTU

Front 33

These inhibit the synthesis of Thyroid Hormones

Back 33

PTU, Methimazole

Front 34

Which Antithyroid is preferred in pregnancy

Back 34

PTU preferred because doesnt cross placenta as easily as methimazole

both Preg cat D

Front 35

Drug Interaction with PTU

Back 35

Oral Anticoagulants

Front 36

This is indicated for Dyspareunia (painful intercourse)

Back 36

Premarin

Front 37

What is in the prempro Combination

Back 37

Premarin and Progestin

Front 38

What estrogen vaginal cream can be substituted for Permarin?

Back 38

Estrace

Front 39

Name Generic, Dose and Indication

Pletal

Back 39

Cilostazol

50,100mg BID

Platelet Aggregation Inhibitor

Front 40

this inhibits PDEIII.This supresses cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, leading to vasodilation and inhibition of platelet aggregation

Back 40

Pletal (Cilostazol)

Front 41

this has a BBW- Contraindicated in patients with CHF

Back 41

Pletal (Cilostazol)

Front 42

Interaction with ______ in Pletal (Cilostazol)

Back 42

CYP450 Inhibitors

Front 43

Alternative for Pletal (Cilostazol)

Back 43

Trental (Pentoxifylline)

Front 44

Name Generic, Dose, and MOA

Plavix

Back 44

Clopidogrel

75mg

selectively inhibits the binding of ADP to its platelet receptor and activation of the glycoprotein GPIIb/IIIa complex thereby inhibiting platelet aggregation

Front 45

Decrease plavix __ days prior to surgery

Back 45

5

Front 46

Alternative for Plavix

Back 46

Ticlid (Ticlopidine)

Front 47

this is a belladonna alkaloid. It inhibits ACh in the vestibular apparatus and input to the CNS

Back 47

Scopolamine

Front 48

this is effective in Motion Sickness

Back 48

Transderm Scop (Scopolamine)

Front 49

how do you use Transderm SCop

Back 49

apply one patch behind the ear about 4 hours before the effect is required. Leave on for 3 days

Front 50

an off label use is for terminally ill patients to dry Bronchial secretions. What is an alternative for this purpose?

Back 50

Atropine Sulfate 1% opthalmic solution

Front 51

Name generic, dose, MOA

Antivert

Back 51

Meclizine

12.5m 25, 50mg

Antihistamine with some anticholinergic action

Front 52

Interaction with Colase, Surfak (Docusate Sodium and Calcium)

Back 52

mineral oil'

Front 53

Name generic. Dose, MOA

Colase

Back 53

Docusate Sodium

50, 100mg cap
syrup 60mg/15ml
liquid 150mg/15ml

facilitates admixture of fat and water to soften stool

Front 54

Name Generic Dose, MOA

Enulose

Back 54

Lactulose

10g/15ml

metabolized by colonic bacteris in colon to mild acids. Increased osmolarity causes osmotic evacuation

Front 55

This binds water and causes water to be retained within the stool

Back 55

MiraLax

Front 56

Miralax Generic

Back 56

PEG 3350