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76 Cards in this Set
- Front
- Back
This is both an Anticholinergic and Benzo
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Librax
Clidinium/Chlordiazepoxide |
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This class should be dosed in the evening at 6pm for best effect
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H2 receptor Agonists
(Tagamet Zantac Pepcid Axid) |
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_________ is the most powerful stimulant of acid production
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Histamine
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Which GI class should be renally adjusted
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H2 antagonists
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THis is the only H2RA that chelates (Cannot take w antacids)
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Tagamet (Cimetidine)
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This H2RA is available in an effervescent tab
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Zantac
(Ranitidine) |
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This H2RA is available as an ODT
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Pepcid (famotidine)
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This class are acid activated prodrugs and should be gicen in association with meals (30-60 min before breakfast..)
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PPIs
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This PPI is used in combo w amox for eradication of H. pylori
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Prevacid (Lansoprazole)
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OTC PPI
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Prilosec
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This is the PPI with the fastest oral absorption
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Prilosec (omeperazole)
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Omeperazole, Sodium Bicarb
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Zegerid
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Isomer of Prilosec
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Nexium (esomeprazole)
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This PPI may be taken with or without food
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Aciphex (Rabeprazole)
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Isomer of Lansoprazole
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Kapidex (Deslansoprazole)
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most PPIs are DR and destroyed by stomach acid if released early... name the one exception
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Zegerid
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this is Aluminum-Sulfated Sucrose
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Sucralfate
(Carafate) |
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Used for Duodenal Ulcers
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Carafate (Sucralfate)
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Counsiling points for Sucralfate
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take with water
60 min before a meal separate from other drugs may cause CONSTIPATION (Al binds to food) |
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This is a Prostaglandin Analog
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Cytotec (Misoprostol)
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This GI Product has an unlabeled use for pregnancy termination (BBW Pregnancy)
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Cytotec (Misoprostol)
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AE of Cytotec
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Diarrhea
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This is a Ach Agonist (GI prokinetic) and DA agonist (Antiemetic)
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Reglan (Metoclopramide)
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SE of Reglan (Metoclopramide)
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Diarrhea, EPS
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ODT Reglan
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Metozolv
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Antiemetic Suppository
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Compazine (prochorperazine)
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This antiemetic is a DA and Ach ANTAgonist
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Compazine (Prochlorperazine)
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This antiemetic Inhibits CTZ
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Tigan (Trimethobenzamide)
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C-V Controlled drug as an adjunct Tx of diarrhea
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Lomotil (Diphenoxylate/Atropine sulfate)
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This drug Activates Cl- Channels and enhances intestinal fliud for the tx of constipation
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Amitiza (Lubiprostone)
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These products are 5-ASAs acting as an antiinflammatory locally on the gut mucosa
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Mesalamine Products
asacol Pentasa Rowasa Canasa Dipentum lialda |
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DESI drug
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Tigan (Trimethobenzamide)
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CI in Parkinsons pts
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Reglan (Metoclopramide)
DA antagonist |
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antiemetic with CNS depression in the elderly
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Reglan (Metoclopramide)
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Prodrugs for Ulcerative Colitis
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Azulfidine (Sulfasalazine)
Colazal (Balasalazide) |
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Check sulfa allergy for this drug
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Azulfidine (Sulfasalazine)
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acts locally on in the colon to dec the inflammatory response and systemically interferes with secretion by INHIBITING PROSTAGLANDIN SYNTHESIS
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Azulfidine (Sulfasalazine)
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Azulfidine is a prodrug that forms into -->
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Mesalamine (5-ASA*) and sulfapyridine
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This is a Budesonide capsule (Glucocorticoid anti-inflammatory drug)
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Entocort E.C.
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These are 5HT3 receptor antagonists
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Zofran (Odansetron)
Kytril (Granisetron) |
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This class of GI drugs should be avoided in pts with alzheimers
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Anticholinergic
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This is two 5-ASA molecules liked by an Azo bond
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Dipentum (Olsalazine)
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Name pancrelipase Brand names
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Pancrease, Ultrase, Creon, Viokase
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This GI Med is contraindicated in pregnant patients
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Cytotec
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Which GI drugs are renally excreted and need adjustments when given to renally compromised patient?
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tagamet
Zantac |
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This GI drug has many DI because it is metabolized by CYP450
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Tagamet
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Name common uses for H2 blockers
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GERD
Heartburn Ulcers |
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Dicyclomine blocks the ______ receptor
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Cholinergic
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Cimetidine blocks the
_____ receptor |
H2
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Misoprostol STIMULATES the _______ receptor
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Prostaglandin
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This antiemetic has a similar structure to Serotonin. It has affinity but no activity at the receptors
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Zofran (Odansetron)
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This class of GI drugs have been used to treat IBS
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Anticholinergics
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this class of GI drugs may relax the LES and contribute to GERD... you may also NOT want to use them on pts with Alzheimers
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Anticholinergics
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Common dose of Bentyl (Dicyclomine)
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10mg PO TID or PRN
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______ is an isomer of atropine
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Levsin (L-hyoscyamine)
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Donnatal
Generic Class Dose |
Belladonna(contains atropine) AND phenobarbital
antispasmotic/ anticholinergic 16.2mg/dose |
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Librax
generic Class |
Clidinium and Chlordiazepoxide
Antispasmotic |
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Tagamet (Cimetidine) dose
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Tagamet HB 200mg
RX:300-400-800mg tabs |
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Which is more potent, Zantac of pepcid
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Pepcid
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Zantac (Ranitidine) dose
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75 and 100mg
RX 150-300mg |
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Pepcid (Famotidine) dose
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20 & 40mg
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Name the products in Pepcid Complete
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famotidine 10mg with calcium carbonate and Magnesium hydroxide
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Name the Products in Prevpac
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Lansoprazole (prevacid)/ amoxicillin/Clarithromycin
used in erradication of H. Pylori infection |
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Caution w all meds that raise pH for prolonged periods of time: may lead to malabsorption of ________
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Vitamin B12
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Carafate Tab and suspension dose
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Tab 1g
Suspension: 1g/10ml |
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MOA of Reglan
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Cholinergic Agoinst(ProKinetic) and DA agonist (Antiemetic)
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Reglan SE
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EPS
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AMITIZA
generic dose indication MOA |
Lubiprostone
8MCG and 24mcg (very small) Chronic Idiopathic Constipation/IBS increases intestinal fluid secretion (increasing motility in the intestine |
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Tigan
generic MOA |
Trimethobenzamide
Inhibits CTZ |
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corticosteroid used in crohns disease
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Encocort EC (Budesonide)
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With This rectal suspension the patient should lie on their left side
dose |
Rowasa
4g/60ml |
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where does 5-ASA work?
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local on the gut mucosa
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Is Mesalamine a salicylate?
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YES
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Azulfidine (Sulfasalazine) has two metabolites... what are they?
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Mesalamine and sulfapyridine
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Dipentum
generic dose |
Olsalazine
250mg : 4 caps BID |
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This is Two 5-ASA molecules linked by an Azo Bond
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Dipentum (Olsalazine)
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