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8 Cards in this Set
- Front
- Back
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How common is PCH?
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Least of all AIHAs; 2%
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What are the 2 forms of PCH?
In whom are they seen? |
Acute - children post-viral inf.
chronic - elderly |
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What is the dat result in PCH?
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Complement only
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What antibody class causes PCH?
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Biphasic Hemolysin, IgG
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What is the name of the antibody that causes PCH?
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Donath Landsteiner antibody
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How does the Donath Landsteiner Ab behave?
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1. Binds RBCs at cold temps
2. Causes hemolysis as it warms 3. Activates complement |
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What is the usual SPECIFICITY of the donath landsteiner Ab?
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Anti-P
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Do transfusions need to be P1 neg then?
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no, only if the patient doesn't respond to P1 pos units.
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