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4 Cards in this Set
- Front
- Back
- 3rd side (hint)
ATROPHY
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Shrinkage of cells
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Physiologic; r/t decreased work load
Pathologic; r/t denervation of muscle, diminished blood supply & nutritional deficiency |
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HYPERTROPHY
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Increase in cell size resulting in enlargement of organs. It Mostly seen in cells that cannot divide, such as skeletal muscle (pumping iron), and cardiac muscle (hypertension). Changes usually revert to normal if cause is removed.
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HYPERPLASIA
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Increased number of cells in an organ or tissue. Hyperplasia may sometimes co-exist with hypertrophy.
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physiologic--hormonal
compensatory--regeneration of liver following partial hepatectomy. Various growth factors and interluekins are important in such hyperplasia. pathologic--excessive hormonal stimulation viral infection (papilloma viruses); neoplasms |
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METAPLASIA
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Transformation or replacement of one adult cell type to another adult cell type (e.g., the change from columnar to squamous cells in respiratory tract, from squamous to columnar in Barrett esophagitis). Also occurs in mesenchymal tissue
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