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6 Cards in this Set

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Hypoxia
Lack of sufficient oxygen. (The single most common cause of cellular injury.)
What are the causes of Hypoxic injury?
Decreased O2 in the air, loss of hemoglobin or it's function, decreased production of RBCs, diseases of the heart/lung systems & poisoning of the oxidative enzymes w/in the cells. Most common cause is Ischemia.
Ischemia
Reduced blood supply.
Anoxia
Total lack of O2.
Reperfusion Injury
Results from the restoration of O2-Cellular damage occurs from the generation of high reactive O2 intermediates, including hydroxyl radical, superoxide, & hydrogen peroxide.
What is Lipid Peroxidation?
Destruction of polyunsaturated lipids leading to membrane damage and increased permeability.