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6 Cards in this Set
- Front
- Back
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Hypoxia
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Lack of sufficient oxygen. (The single most common cause of cellular injury.)
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What are the causes of Hypoxic injury?
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Decreased O2 in the air, loss of hemoglobin or it's function, decreased production of RBCs, diseases of the heart/lung systems & poisoning of the oxidative enzymes w/in the cells. Most common cause is Ischemia.
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Ischemia
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Reduced blood supply.
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Anoxia
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Total lack of O2.
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Reperfusion Injury
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Results from the restoration of O2-Cellular damage occurs from the generation of high reactive O2 intermediates, including hydroxyl radical, superoxide, & hydrogen peroxide.
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What is Lipid Peroxidation?
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Destruction of polyunsaturated lipids leading to membrane damage and increased permeability.
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