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22 Cards in this Set

  • Front
  • Back
the science of study of disease

also a clinical specialty in human medicine
2 divisions of pathology
anatomic pathology

clinical pathology
anatomic pathology
surgical, cytolog, necropsy
clinical pathology
clinical chemistry, clinical microbiology, hematology, blood bank, immunology
pathology emphasizes
emphasizes the measurable aspects of disease, such as altered structure of cells, tissues, and organs (gross & microscopic) and lab findings
pathology draws from what sciences?
basic and clinical sciences; anatomy, physiology, biochemistry, cell and molecular biology, genetics, pharmacology, and pathology
how is pathophysiology different from other biomed sciences?
focus on the mechanisms of disease or the dynamic processes the give rise to the signs and symptoms
why do health care practitioners need to understand the mechanisms of disease?
interpretation of signs and symptoms, appropriate treatment, and prevention are logically related to knowing the disease
normal and disease
are complex and to an extent arbitrary and influenced by cultural values, as well as biologic factors
define disease
a failure of the organism to adapt or to maintain homeostasis; it is actually the sum of the physiologic processes that have been distorted
where does disease come from
often disease begins within the adaptive mechanisms of the body that have the potential to result in a good or bad outcome
- the study of causes or reasons for phenomena

- complex b/c most diseases are multifactorial and result from an interaction of intrinsic or genetic and environmental factors
knowing the cause of disease is important because...
without knowing the cause prevention would be very difficult
the sequence of events in the development of a disease from its earliest beginnings, including factors influencing its development
natural history of a disease
its usual course from beginning to end without treatment
a demonstrable structural change in the tissues produced by disease that is evident at a gross or microscopic level
observable (objective) clinical manifestations of disease, such as a heart murmur, hypertension, fever or a palpable mass
subjective feelings that something is wrong and can be reported only be the patient to an observer
ex. pain, nausea, vertigo, lethargy
sequela, sequelae (pl.)
the outcome or aftereffect of a disease or injury

ex. the sequela of acute rheumatic fever might be scarred and deformed heart valves
complication of disease
an accidental condition or second disease occurring in the course of a primary process
the subsidence of a disease process, as inflammation, and the return to normal of affected tissues
classification of diease
organ system or etiologic categories

any disease may include more than one category at one time