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16 Cards in this Set
- Front
- Back
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Etiology of acute GN
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in the setting of infectious disease - pharyngeal or cutaneous infection with group A beta-hemolytic streptococci (but also other pathogens)
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Etiology of rapidly progressive GN
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Heterogenous group of disorder with rapidly progressive kidney failure (e.g., necrotizing vasculitis)
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Etiology of chronic glomerulonephritis
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heterogenous group of disorders leading to CRF
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Etiology of nephrotic syndrome
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Variant of acute GN, rapidly progressive GN or chronic GN with massive proteinuria (e.g., minimal change disease)
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Etiology of asymptomatic urinary abnormalities
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IgA nephropathy (Berger's disease) - immune complex disease with diffuse mesangial IgA deposition
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Symptoms of nephritic syndrom
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Proteinuria
Hematuria Azotemia RBC casts Oliguria Hypertension |
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Symptoms of acute GN usually appear
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7-10 days after onset of acute pharyngeal or cutaneous infection
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Symptoms of acute GN
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1. Fatigue
2. Back pain 3. Mild to severe HTN - decreased GFR, sodium retention, or inappropriate release of renin 4. Oliguria (decreased GFR) 5. Micro or macro-hematuria 6. Proteinuria 7. Cough, with sputum (pharyngeal infxn) |
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Nephritic syndrome usually appears in
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1. Acute GN
2. RPGN 3. IgA nephropathy |
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Nephrotic syndrome usually appears in
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1. Minimal change disease
2. Membraneous nephropathy |
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In which age group is AGN most common?
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Children 3-10 years old
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Complications of AGN
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1. Pulmonary edema
2. Heart failure 3. Sepsis 4. Severe HTN 5. Cardiac hypertrophy 6. Nephrotic syndrome 7. Chronic GN 8. Renal failure 9. ESRD |
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Which test is used to confirm GN
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Kidney biopsy confirms post-streptococcal GN, but biopsies are usually not necessary
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30-40% of patients with RPGN have granular Ig deposits and antibody pattern typical of _____ . 5-20% of patients have linear anti-GBM antibody deposits in glomeruli, this is called ____ .
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1. Wegener's granulomatosis
2. Goodpasture's syndrome |
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What is Goodpasture's syndrome
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1. A disease that affects kidneys and lungs
2. Involves rapidly progressive kidney failure that develops in days to weeks along with lung disease 3. Cough, shortness of breath, and blood in sputum |
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RPGN symptoms
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1. Edema
2. Dark or smoke-coloured urine 3. Decreased urine volume 4. Other symptoms |
