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18 Cards in this Set
- Front
- Back
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Macrophages |
monocytes - blood macrophages - tissue engulf and digest foreign material stimulate cytokines -> inflammatory response present antigen to lymphocytes |
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Lymphocytes |
WBC that acts as specific antigen/pathogen specific types make antibodies to fight infection |
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Natural Killer Cells |
Lymphocyte type Doesn't need to recognize antigen to kill is neither a B or T lymphocyte triggers phagocytes to come to site |
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T Cells |
Lymphocyte type cell mediated immunity recognize MHC, major defender against cells, orchestrates an immune response |
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Helper T cells |
CD4 cell initiate and orchestrate immune response causes B cell proliferation/maturation->Ab production->activity of cytotoxic T cells, other T cells, and macrophage system |
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Activated (Killer) T cells |
cytotoxic T lymphocytes CD8 kills cells with lyphokines count rises sharply during acute HIV infection and remains elevated over course of disease |
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B cells |
Lymphocyte type humoral immunity produce specific Ab -> Ag is recognized by APC and presented to T cell T cells activate B cells Plasma cells secrete Ag specific Ig |
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Type I Hypersensitivity reaction |
Allergic/Anaphylactic Histamine release causes bad reaction |
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Type II Hypersensitivity reaction |
Cytotoxic Ag presented on cell and IgG Ab reacts with non-foreign Ag and kills cell given wrong blood type |
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Type III Hypersensitivity reaction |
Immune complex introduction of drugs/foreign proteins that causes Ag-Ab complexes to form |
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Raynaud phenomenon |
Type III hypersensitivity reaction temperature dependant |
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Arthus reaction |
Type III hypersensitivity reaction repeated local exposure to exogenous Ag through: Ingestion - Celiac disease (gluten intolerance) Inhalation - Fungus (Farmer's lung) |
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Type IV Hypersensitivity reaction |
Cell mediated (delayed) late reaction to Ag (48-96 hrs) Examples: Purified Protein Derivative (PPD), Allergic dermatitis (poison ivy), transplanted graft (organ) rejection |
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Acquired immunity |
2 types: Cell mediated and Humoral |
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Cell mediated immunity |
T cells direct cell destruction memory: delayed hypersensitivity T cells |
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Humoral immunity |
B cells produce specific antibodies IgA: body secretions IgD: increase in chronic infection IgE: hypersensitivity, allergies, and parasites |
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Host rejects organ |
due to human leukocyte antigen more common form of organ rejection |
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Graft (organ) rejects host |
T cells within graft attack host cells |
