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26 Cards in this Set
- Front
- Back
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What are the 4 structures of the immune system?
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-skin
-phagocyte system -lymphoid system: spleen, lymph nodes -bone marrow |
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What is considered the "first line of defense" of the body?
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-skin and mucous membranes
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What is the role of IgA in epithelial barriers?
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-bind antigens on surface to prevent antigens from entering deeper tissue
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What are dendritic cells?
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-monocyte derived cells that capture and present antigens to T-cells
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Macrophages and Dendritic cells are first to...
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encounter pathogens and foreign bodies after they have entered the body.
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Hematopoiesis is the
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formation of blood cells
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Red Bone Marrow is located
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in the pelvis, sternum, ribs, and cranium
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Lymph Nodes
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carry fluids and protein and return them to circulation
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Spleen
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filtering function of the blood.
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Neutrophils
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are early responders to acute infection and arrive in large numbers
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Eosinophils are
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associated with allergic reactions and intestinal parasites; main purpose is to destroy helminths (parasites)
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Basophils
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migrate to connective tissue and bind to IgE bodies to create pro-inflammatory responses.
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Monocytes
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mature into macrophages which actively phagocytize large foreign particles.
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What is an antigen?
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-substance capable of producing an immune response.
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Kinins are
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a small polypeptide that cause vasodilation and have a role in clotting factors.
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Humoral Immune Response
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is the antibody mediated immune response produced by B-lymphocytes
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Cell Mediated Immune Response
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immune response to antigens that does not evoke the Humoral Immune Response.
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Antibodies are
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proteins produced by B cells that destroys or inactivates a specific antigen
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Macrophages and T-helper cells
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are the main source of the immune system cytokines.
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1.Granulocytes
2.Neutrophils 3.Eosinophils 4.Basophils 5.Monocytes |
1. 60-80%
2. 55-70% 3.1-4% 4.0.5-1% 5.2-3% |
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What does a dendritic cell do?
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Process antigen material and present it on the surface to other cells of the immune system.
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What is the function of a Basophil?
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Appear in many inflammatory reactions, and contain histamine to reduce the onset of allergic reactions.
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What is the function of a neutrophil?
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the first-responders of inflammatory cells to migrate towards the site of inflammation
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What are leukocytes?
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cells of the immune system involved in defending the body against both infectious disease and foreign materials
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What is the function of a macrophage?
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remove necrotic cellular debris, by engulfing the antigen and destroying it
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What is an antigen?
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is a substance or molecule that, when introduced into the body, triggers the production of an antibody by the immune system, which will then kill or neutralize the antigen that is recognized as a foreign and potentially harmful invader
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