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17 Cards in this Set
- Front
- Back
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Pyogenic bacterial infections and tissue necrosis, are associated with which leukocytes?
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They are associated with infiltrates of neutrophils into tissue and increased numbers of neutrophils in the blood, hence they are considered acute inflammatory cells.
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What are PMNs?
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Polymorphonuclear leukocytes or polys, because they characteristically have nuclei with 3-5 lobes.
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What is myeloperoxidase?
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It is an enzyme within the primary(azurophilic) granules of neutrophils.
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What is Alk-phos?
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It is alkaline phosphatase, and it is an enzyme in their secondary specific granules.
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Neutrophils have a short life span and do not divide. TRUE/FALSE
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TRUE.
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What are monocytes?
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They are mononuclear leukocytes with a bean shaped or horseshoe shaped nucleus.
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The activated form of macrophages have what type of cytoplasm?
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Eosinophilic and are called epithelioid cells. They secrete many different types of products and may fuse to form giant cells.
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What are lymphocytes?
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They are smaller mononuclear leukocytes that ave a round to oval nucleus and little cytoplasm.
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What are the two types of lymphocytes?
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B and T lymphocytes. They look histologically identical.
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What do B lymphocytes do?
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They mature into plasma cells, which have an eccentric nucleus with a clock face appearance of their chromatin. Plasma cells secrete immunoglobulins, while certain T lymphocytes(T cells) secrete lymphokines.
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Numbers of lymphocytes are increased in acute viral infections or chronic disease. TRUE/FALSE
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TRUE.
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What are eosinophils?
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They are bilobed leukocytes that contain abundant eosinophilic granules within their cytoplasm.
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What do eosinophilic granules contain?
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They contain many different types of substances such as major basic protein(which is toxic to helminthic parasites), arylsulfatase(which neutralizes leukotrienes) and histaminase(which neutralizes histamine.
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What role do eosinophils play?
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They participate in specific types of inflammatory processes, such as allergic disorders, parisitic infections, and some skin diseases.
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What are basophils?
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They are a leukocyte that have numerous deeply basophilic granules within their cytoplasm that completely hide the nucleus.
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What do basophils participate in?
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In certain types of immune reactions because they have surface receptors for IgE. When activated they release vasoactive substances such as histamine.
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Mast cells, although not exactly the same as basophils, are found in tissue and are very similar to basophils. TRUE/FALSE
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TRUE.
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