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4 Cards in this Set
- Front
- Back
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Diabetes Mellitus Type 1. hypersensitivity type? antigen?
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Type 4.
pancreatic islet Beta cells act as antigens (specifically glutamic acid decarboxylase, insulin, etc) so of course clinically see insulitis (islet chronic inflamm, destruction of beta cells). |
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Multiple Sclerosis. hypersensitivity type? antigen? describe disease manifestations.
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Type 4.
CNS myelin antigens (myelin basic protein, proteolipid protein) demyelination. perivascular inflamm. ocular lesions |
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Rheumatoid arthritis. hypersensitivity type? antigen?
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Type 4.
antigen in joint synovium. SEE CARTILAGE/BONE DESTRUCTION. versus SLE associated arthritis. |
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Peripheral neuropathy; Guillain-Barre syndrome. Hypersensitivity type? antigen?
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Type 4.
peripheral nerve myelin antigen. neuritis. paralysis. |
