Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
|
Gastrin
action? site of release? stimulus for release? any associated diseases? |
actions:
-acid secretion stimulation - growth of gastric oxyntic gland mucosa released: gastric antrum + duodenum stimulus for release: peptides, aa, distention, vagal stim disease: zollinger-Ellison syndrome, PUD |
|
|
CCK
action? site of release? stimulus for release? any associated diseases? |
action:
- stimulates gallbladder contraction - pancreatic enzyme and bicarb secretion - growth of exocrine pancreas site of release: duodenum/jejunum stimulus for release: peptides, aa, long chain FAs (acid) any associated diseases: no |
|
|
Secretin
action? site of release? stimulus for release? any associated diseases? |
action:
- stimulates panreatic and biliary bicarb secretion - growth of exocrine pancreas - inhib gastric acid secretion, trophic effects of gastrin site of release: duodenum stimulus for release: fat (acid) any associated diseases: no |
|
|
Gastric Inhibitory Peptide (GIP)
action? site of release? stimulus for release? any associated diseases? |
action:
- stimulates insulin release - inhibits gastric acid secretion site of release: duodenum/jejunum stimulus for release: glucose, aa, fatty acids any associated diseases: no |
|
|
Motilin
action? site of release? stimulus for release? any associated diseases? |
action: stimulates gastric and duodenal motility
site of release: duodenum/jejunum stimulus for release: unknown any associated diseases: - irritable bowel sydrome - diabetic gastroparesis |
|
|
Pancreatic Polypeptide
action? site of release? stimulus for release? any associated diseases? |
action: inhibits pancreatic bicarb and enzyme secretion
site of release: pancreatic islets of langerhans stimulus for release: protein (fat and glucose) any associated diseases: no |
|
|
Enteroglucagon
action? site of release? stimulus for release? any associated diseases? |
action: elevates blood glucose (?)
site of release: ileum stimulus for release: glucose, fat any associated diseases: no |
|
|
Somatostatin
action? site of release? stimulus for release? any associated diseases? |
action: inhibits release of most other peptide hormones
site of release: - GI tract mucosa - pancreatic islets of langerhans stimulus for release: acid stimulates, vagus inhibits release any associated diseases: gallstones |
|
|
Prostaglandins
action? site of release? stimulus for release? any associated diseases? |
action:
- promote blood flow - increase mucus and bicarb secretion from gastric mucosa site of release: various stimulus for release: various any associated diseases: NSAID induced gastritis and ulcers |
|
|
Histamine
action? site of release? stimulus for release? any associated diseases? |
action: stimulates gastric acid secretion
site of release: oxyntic gland mucosa stimulus for release: uknown any associated diseases: no |
|
|
Vasoactive intestinal peptide (VIP)
action? site of release? stimulus for release? any associated diseases? |
action:
- relaxes sphincter and gut circular muscle - stimulats intestinal and pancreatic secretion site of release: mucosa and smooth muscle of GI tract stimulus for release: enteric nervous system any associated diseases: secretory diarrhea |
|
|
Bombesin
action? site of release? stimulus for release? any associated diseases? |
action: stimulates gastrin release
site of release: gastric mucosa stimulus for release: enteric nervous system any associated diseases: no |
|
|
Enkephalins
action? site of release? stimulus for release? any associated diseases? |
action:
-stimulates smooth musc contraction - inhibits intestinal secretion site of release: mucosa and smooth musc. of GI tract stimulus for release: enteric nervous system any associated diseases: no |
|
|
Intrinsic Factor
action? site of release? stimulus for release? any associated diseases? |
action: binds to vit b12 to facilitate absorption
site of release: parietal cells of stomach stimulus for release: constitutive secretion any associated diseases: AI destruction --> pernicious anemia |
|
|
Mucin
action? site of release? stimulus for release? any associated diseases? |
action: lubrication and protection
site of release: goblet cells along entire GI tract mucosa stimulus for release: GI tract irritation any associated diseases: viscid mucus in cystic fibrosis; attenuation in some case of peptic ulcer |
|
|
Acid
action? site of release? stimulus for release? any associated diseases? |
action: prevents infection, initiates digestion
site of release: parietal cells of stomach stimulus for release: gastrin, histamine, Ach, NSAIDS (indirect) any associated diseases: Acid peptic disease |
