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76 Cards in this Set
- Front
- Back
- 3rd side (hint)
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tetracycline
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microvesicular fatty change
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salicylates
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micrivesicular FC
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yellow phosphorus
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microvesicular FC
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ethanol
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Microvesicular or macrovesicular FC
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methotrexate
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macrovesicular fatty change
fibrosis-cirrhosis antifolate = megaloblastic anemia |
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amiodarone (class 3 beta blocker for arrythmias)
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macrovesicular fatty change
fibrosis/cirrhosis pneumitis leading to pulmonary fibrosis |
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bromobenzene
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centrilobular necrosis
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CCl4
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centrilobular necrosis
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acetaminophin
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centrilobular necrosis
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halothane
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centrilobular necrosis
diffuse/massive necrosis |
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rifampin
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centrilobular necrosis
thrombocytopenia, neutropenia red tears/orange urine |
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isoniazid
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diffuse/massive necrosis
hepatitis (acute/chronic) hemolysis IC type |
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methyldopa
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diffuse/massive necrosis
granuloma formation hepatitis (acute/chronic) |
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trinitrotuluene
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diffuse/massive necrosis (military/explosives)
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Amanita phalloides (mushroom toxin
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diffuse/massive necrosis
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nitrofurantoin
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hepatitis (acute/chronic)
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phenytoin
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hepatitis (antiepileptic, also folic acid def)
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oxyphenisatin
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hepatitis
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sulfonamides
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granuloma formation
hemolysis: IC type |
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quinidine
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granuloma
hemolysis: IC type |
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phenylbutazone
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granuloma (type of NSAID)
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hydralazine
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granuloma (smooth muscle relaxant, HTN)
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allopurinol
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granuloma
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chlorpromazine
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cholestasis
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anabolic steroids, oral contraceptives
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cholestasis
acute pancreatitis |
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erythromycin estolate
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cholestasis
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oral contraceptives
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cholestasis
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organic arsenicals (pesticides)
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cholestasis
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theophylline (asthma drug)
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decrease LES (reflux)
hyponatremia hypokalemia |
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PGE2, PGI2
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decrease LES pressure (reflux)
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Medperidine
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decrease LES pressure (reflux)
opiod resp depression (acidosis) |
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morphine
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decrease LES pressure (reflux)
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diazepam
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decrease LES pressure (reflux)
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Calcium channel blockers
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decrease LES pressure (reflux)
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barbiturates
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decrease LES pressure (reflux)
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antacids
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increase LES pressure
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metoclopramide
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increase LES pressure
(so you don't vomit! antiemetic) |
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domperidone
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increase LES pressure
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PGF2
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increase LES pressure
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digitalis
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diarrhea
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propanalol
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diarrhea
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quinidine
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diarrhea and granulomas in liver
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diuretics
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diarrhea
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cholchicines
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diarrhea (FORMER QUESTION)
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antibiotics
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diarrhea
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antacids (maalox)
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diarrhea
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chemotherapeutic agents
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diarrhea
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bile acids
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diarrhea
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meclomen
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diarrhea
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azathioprine (immune suppressant)
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acute pancreatitis
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mercaptopurine (antineoplastic)
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acute pancreatitis
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captain's pancreatitis
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thiazides
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acute pancreatitis
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hyperlipidemia! so of course this
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sulfonamides
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liver granulomas and acute pancreatitis
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tetracyclines
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microvesicular fatty change
acute pancreatitis |
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pentamidine (for PCP, dry walking cough of 29 year old female. or could use TMP-S for it)
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acute pancreatitis
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didanosine
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acute pancreatitis
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metronidazole
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acute pancreatitis
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erythromycin
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acute pancreatitis
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estrogen/oral contraceptives
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gallstones (cholestasis) and acute pancreatitis
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corticosteroids
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acute pancreatitis
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valproic acid
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acute pancreatitis
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metformin (oral antidiabetic)
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acute pancreatitis
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IV lipid infusion
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acute pancreatitis
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hemachromatosis
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iron.
metabolic acidosis w/ increased ion gap. pancreatitis. |
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dilated cardiomyopathies
restrictive cardiomyopathies |
dilated: infection (viral)
CT disease peripartum sarcoidosis alcoholism chemotherapeutic agens (doxorubicin) hypothyroidism hypocalcemia or hypophophatemia chronically muscular or myotonic dystrophy (muscular dystrophy also causes NM type of restrictive pulmonary disease w/ decrease in tidal volume) Restrictive: scleroderma amyloidosis sarcoidosis hemachromatosis glycogen storage diseases endomyocardial fibrosis radiation hypereosinophilic syndrome |
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valsalva maneuver
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decreases size of LV (decreases the venous return or something p 263 lily)
so if hypertrophic cardiomyopathy, murmur increases b/c leaflet closer to wall if aortic stenosis murmur, murmur lessons |
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Iron deficiency anemia
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decrease MCH, MCHC, MCV
see in chronic bleeding |
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malab via pancreatitis. no fat vitamins. ADEK, K for clotting factors so...
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prolong PT and PTT. bleeding time normal
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cor pulmonale and hemodynamic values
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- decrease LV end diastolic volume
- but stroke volume of left ventricle fine - ejection fraction fine too (hear working fine! unlike long term congestive heart failure) - PCWP aka left atrium pressure decreased (blood backed up in right heart, not getting there) - peripheral vascular resistnace increased because trying to compensate and raise blood pressure b/c it wnats to be low naturally b/c no blood there! |
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systolic murmur radiating into carotids
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aortic stenosis probably
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african american w/ joint pain and chronic jaundice
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sickle cell.
can predispose to cholethiasis |
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rbc destruction:
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decreased hematocrit, but increased retics. normocytic normochromic
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Heme: Reticulocytes. 3 situations
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1. destruction of rbcs (thalassemia, sickle cell). increased. normochromic, Hct decreased
2. making problem (folate def, lead, etc). decreased retics (duh b/c making problem) 3. hypoxic conditions. Hct decreased. increased retics b/c secondary polycythemia so Hct increased |
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Drug induced Lupas
• High risk: •Procainamide (antiarrhythmic) Hydralazine (antihypertensive) • Moderate to low risk: • Isoniazid (antibiotic) • Minocycline (antibiotic) • Pyrazinamide (antibiotic) • Quinidine (antiarrhythmic) • D-Penicillamine (anti-inflammatory) • Carbamazepine (anticonvulsant) • Oxcarbazepine (anticonvulsant) • Phenytoin (anticonvulsant) • Propafenone (antiarrhythmic) |
anti histone characteristic, but can also have the systemic sclerossis (SCL 70 top isomerase)
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cirrhosis
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by this time liver enzymes gone so neutral.
can't conjugate biliburin b/c lost hepatocytes CHOLESTEROL DECREASED |
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chloramphenicol
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aplastic anemia
(decreased retics, normochromic/cytic) |
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