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12 Cards in this Set

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  • Back
What is the purpose of vaccines
To induce long-lasting protective immune responses not resulting in disease.
What is the primary mechanism of vaccines
Primary response is shortlived. May need boosters to increase immune response, numbers of memory cells and sustained protective levels of antibodies, T cells, or both.
What are live attenuated vaccines
Weakened forms of the pathogen. Usually viral. Ex: MMR, varicella. Cause a limited, easily controlled infection.
What are killed vaccines
Inactivated pathogen. Ex: Hep A. Cannot cause infection.
What is an example of a recombinant viral protein vaccine
Hep B. Purified viral antigen.
What are bacterial antigen vaccines.
Ex: pneumococcal pneumonia. Contains a mix of capsular polysaccharides from 10 strains.
What are toxoid vaccines
Purified, inactivated toxin that create an immune response. Ex: TDaP
What are MOAs of antibiotics
Prevent function of enzymes and damage bacterial structures, inhibit cell wall synthesis, damages cytoplasmic membrane, alters metabolism of nucleic acids, inhibits protein synthesis, modulates energy metabolism
How does penicillin work
Inhibits cell wall synthesis
How does HIV work
Suppresses immune response, rapid antigenic changes
How has TB adapted
Multidrug resistance
How does C.dif work
Treatment with clindamycin, causes overgrowth of C. dif, causes pseudomembranous colitis