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21 Cards in this Set
- Front
- Back
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the majority of your WBCs are composed of
a) neutrophil b) basophil c) monocytes d) lymphocytes |
Neutrophil 50-60%
Lymphocytes 20-30% |
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list the components of the lymph system
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lymph vessels, nodes
lymph tissue (SP, thymus) |
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____ = xs of body fluids
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lymph
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list the causes of neutropenia
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Low WBC due to
aplastic marrow drug rxn hyersplenism cancer therapy |
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list the causes of granulocytosis
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Xs WBC due to
inflammation infection |
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recurrect respiratory infections is a common manifestation of
a) neutropenia b) granulocytosis c) EBV d) leukemia |
neutropenia
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incorrect statement about neutropenia
a) Neutrophil <15000 b) G-CSF for tx b) infection of B cells d) none of the above |
infection of B cells = infectious mono
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T/F
if left untreated with mono- EBV will continue to proliferate |
F
self limiting lympho-prolif disorder |
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describe he pathogenesis of mono
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-EBV invades B cells of tonils/lymph tissue
-EBV replicates inside and causes death of B cells -EBV released in blood -immunologic response -infected B cells display virus directed membrane antigen -CD4/CD8 proliferation causes swollen lymph nodes/SP/LV |
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what is not true about mono
a) long incubation b) flu like syndrome c) leukocytosis d) all are true |
all
incubation- 4-8 weeks prodromal symptom= flu like lab test = leukocytosis (predom lymphocytes) |
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define leukemia
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malignant neoplasm of hematopoietic stem cells -> large # of immature WBCs in peripheral blood
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list the types of leukemia
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lymphocytic (ALL, CLL)
myelocytic (AML, CML) |
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depressed bone marrow function causes
a) acute leukemia b) chronic leukemia c) infectious mononucleosis d) none of the above |
acute leukemia
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list the symptoms of acute leukemia
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malaise, lethargy
weight loss fever, nite sweat bone/joint pain swollen lymphnodes/SP/LV |
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true statement about acute leukemia
a) leukocytosis w blast cell circulation b) hyperuricemia c) uric acid nephropathy d) all |
all
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list treatment options for acute leukemia
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chemo
radiation bone marrow transplant |
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T/F
ALL is most common in children and young adults |
T- responds well to bone marrow transplant 70% curable
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incorrect statement about AML
a) occurs mainly in adults, esp >60 b) lymphadenopathy is uncommon c) related to underlying congenital disorders or toxins |
lymphadenopathy incommon = CML
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T/F
CLL occurs mainly in children and young adults |
F- occurs in old
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exists in chronic, accelerated, acute or blast stage
a) ALL b) AML c) CLL d) CML |
CML
all elemnts of bone marrow are involved poor prognosis |
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incorrect statement about CML
a) poor prognosis b) all elements of bone marrow involved c) related to underlying toxins/congenital disorders |
related to underlying congenital disorders = AML
CML: no swollen lymph nodes 30% living post diagnosis 3-4 yr survival |
