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13 Cards in this Set

  • Front
  • Back
1. Definition: Etiology/Pathogenesis
a. Causes of changes producing disease
2. Definition: Pathophysiology
a. Mechanisms and morphologic alterations
b. Nature of the disease, how it progresses
3. Definition: Prognosis
a. Effect on a person
b. Probable outcome of the disease
4. Definition: epidemiology
a. Who tends to be affected
5. What is homeostasis?
a. Maintenance of structural and functional status quo
b. Regulation of the body in a balance by adjusting to internal and external stressors via inherent mechanisms of the cell, tissue, organ, systems, and body
6. What is Allostasis?
a. Maintaining body stability and viability through CHANGE
b. Change may be permanent
7. What would be an example of allostasis in the heart?
a. Hypertrophy
8. What is Allostatic Overload?
a. Response to stressors that overwhelm inherent homeostatic or allostatic mechanisms
b. Result in PATHOLOGIC structure/function alterations
9. What is characteristic nature of a disease?
a. How the disease generally appears in most people
10. What is a N:C ratio?
a. Nucleus relative to a cell’s cytoplasm
b. Used to detect neoplastic changes
11. What is the central dogma of molecular biology?
a. DNA to RNA to PROTEIN
12. What is the central dogma of Health and Disease?
a. Risks
i. Pathogenesis/etiology
1. Pathophysiology
a. Prognosis/natural history
14. Causes of disease and DDx (think mnemonic)
a. VINDICATE
i. Vascular
ii. Infectious
iii. Neoplastic
iv. Drugs
v. Immunologic/autoimmune
vi. Congenital/genetic
vii. Acid/base; metabolic
viii. Trauma/toxic/occupational
ix. Endocrine