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22 Cards in this Set

  • Front
  • Back
apoptosis
programmed cell death of individual cells
benign
an innocent type of neoplasm; non-agressive and non-spready but CAN be space-occupying
cancer
malignant tumour of epithelial origin
carcinogen
chemical or other agent capable of causing cancer
carcinoma
malignant tumour of epithelial cells
contact inhibition
restriction on cell growth which occurs when the cells come into contact with other cells
differentiation
dvp of a specialised state, with expression of appropriate markers
dysplasia
abnormality of dvp or formation
hamartoma
focus of exaggerated normal or hyperplastic tissue components stimulating a tumour mass
leukaemia
malignant neoplasm of circulating WBC; includes bone marrow as well as circulating WBCs
lymphosarcoma
malignant neoplasia of the lymphocytes in the organised lymphoid tissues (ex. ln, spleen); can affect bone marrow less commonly
malignant
an aggressive, uncontrollable, infiltrating neoplasia, often spreading to other organs
metastasis
phenomenon of spread of tumour cells from a primary site to one or more (usually multiple) distant sites (usually other parenchymatous organs)
neoplasia
any disorder of cell proliferation resulting in uncontrolled cell growth
neoplasm
the group of cells resulting from neoplasia - usually but not always a tumour
oncogene
gene which is capable of causing xformation of cells in which it is aberrantly expressed
oncology
study of tumours or neoplasms
senescence
decline in cell viability and cell death assd with old age or multiple cell cycles - immortalised cells do not senesce
sarcoma
a malignant tumour of CT cells
xformation
occurs when a cell loses contact inhibition and anchorage dependence. xformed cells are not necessarily immortalised or tumourogenic
tumour
a solid cell mass formed within tissues by neoplasia, and not affected by the regulatory processes which exist in wound healing
tumourogenic
cells which when injected into an animal or tissue are capable of forming a tumour; chemicals which will induce a tumour