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19 Cards in this Set

  • Front
  • Back
What are the characteristics of Scarlet Fever?
-Group A strep.
-strawberry tongue
-diffuse erythmatous rash
-desquamation of the skin 1 week after onset.
What are the bacterial characteristics of Group A strep?
-gram + cocci
-facultative anaerobes
-ferment glucose to lactose
-sensitive to bacitracin
Which factors act as protection for the group A strep?
--M protein (antiphagocytic)
-lipoteichoic acid (cell wall regidity and attachement to epithelium)
-Peptidoglycan wall
-group carbohydrates.
What factors act as defense agents for group A strep?
-streptokiinase (lyses fibrin)
-hyaluronidase and proteinase- spreads infection
-NADase- leukotoxic
-Hemolysins
What is the Therapy for Group A strep?
- Penicillin G or Penicillin V for 10 days.

-Macrolides( erythromycin or azithromycin) or cephalosporins.

-some infections have beta-lactamase producing organisms that protect from penicillin.
What are the 3 major etiologic agents for epiglotitts?
-Strep Pyogenes

-Haemophilus influenzae B

-Staph aureus
What is the treatment of choice for epiglotitis?
-Ceftriaxone!

-intubate if in the ER/OR

-Hib vaccine
What is the epidemiology of Diptheria?
less than 10 cases/yr in the US d/t vaccine
disease of infants and children
What is the pathogenesis of Diptheria?
-toxin absorbed by droplet infection, destroys epithelium and induces strong inflamm.

-necrotic epithelium + fibrin + blood makes a gray pseudomembrane over tonsils

-Toxin absorbed into bloodstream infecting heart, liver, kidneys, adrenals and peripheral nerves.
What is the Tx of choice for diptheria?
Penicillin

-also immunization (DTaP) at 2,4,6,18 mo and 4-6 yrs.
What are bacteriological characteristics of bordetella pertussis?
-small gram - coccobacilli
-strict aerobes!
-kills ciliated epithelial cells
What is the Tx for pertussis?
Erythromycin

DTaP vaccine.
Which agent causes major weight loss in TB?
TNF which interferes with lipid metabolism
Which agent causes fever in the manifestation of TB?
Interleukin 1 mediates fever!
What is the most common disease of the nasopharynx?
nasopharyngeal carcinoma.
-EBV
-seen in Asia/China
-diplopia, otitis media, epistaxis and cervical node enlargement.
What is the most common problem in the oropharynx?
What is the tx?
Pharyngitis (involving the lingual tonsils faucial tonsils and adenoids)
-penicillin for acute bacterial
-cefuroxime axetil is more effective for primary tx.
*if allergic to penicillin, use azithromcin.
What is the condition usually due to when a pt presents with:
sore throat, foul breath, halitosis, white yellow debris.?
Tonsils with deep crypts or crevices.
-susceptible to anaerobic infections especially group A streptococcus.
What is the typical treatment for thrush?
-Topical: clotrimazole or nystatin

-Systemic: fluconazole
What underlying conditions can cause thrush?
immuno D
diabetes
prolonged use of antibiotics
xerostomia