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35 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
What are the 4 features which determine inflammatory classification
Organ involved
Onset and course
Architectural pattern
Type of exudate
Side 2: What is the response to viruses
Side 3: What is the classification of inflammation
Immune mediated responses
mononuclear and nonsupppurative
(Lymphocytes and plasma cells )
Side 2: What is the response to extracellular bacteria
Side 3: What is the classification of inflammation
Phagocytosis and killing
Suppurative
(Pus or purulent exudate)
What is the response to Intracellular bacteria, fungi
Granulomatous respones
(epithelioid macrophages and giant cells)
Side 2: What are the 4 classifications of inflammatory response based on time
Side 3: What is the time frame for each stage
Peracute, acute, subacute, chronic
Peracute - rapid and severe
Acute - min. to 48 hours (exudative phase)
Subacute - 3-7 days (exudative and early proliferative features)
Chronic - >7 days (proliferative - fibroplasia)
Describe what is seen in focal/multifocal inflammation
One or multiple foci of discrete inflammation in an organ
Describe what is seen in locally extensive inflammation
Major part but not all of an organ is inflamed
Describe what is seen in diffuse inflammation
All or nearly all of an organ or part inflamed
Describe what is seen in interstitial inflammation
Inflammation focused on interstitium of an organ (eg. kidney, lung)
Describe what is seen in generalized inflammation
Somewhat redundant with "diffuse" and less desirable. Diffuse inflammation of multiple organs or surfaces
Side 2: Describe necrotic inflammation
Side 3: Where does it generally occur
Inflammatory reaction in which substantial necrosis occurs acutely
Pale yellow to white or gray necrotic tissue separated from viable tissue by a sharp red inflammatory border
Inflammed tissue separated from viable tissue with difficulty
Intestine, mouth, liver
What is erosion
Necrosis or loss of mucosa that etends to but not through the basement membrane
(erosive stomatitis, enteritis)
Side 2: What is an ulcer
Side 3: what is the mechanism of action
Necrosis or loss of mucosa that extends through the basement membrane
(Ulcerative stomatitis, enteritis, keratitis)
enzymatic digestion of inflamed tissue leads to sloughing revealing an ulcer often bordered by a red rim of inflammation
Side 2: What are the characteristics of serous exudate
Side 3: What is its purpose
Clear, watery exudate (may be faintly yellow) with low protein content; mild inflammatory response
Dilute toxins, contain antibodies
Good environment for bacterial growth
Side 2: What are the characteristics of fibrinous exudate
Side 3: How does the organ appear
Yellowish, opaque, adherent, elastic, friable exudate; severe inflammatory response
dull, granular, slightly frosted appearance
Fibrinous exudate peels easily from surfaces without bleeding
Side 2: What is the terminology for the formation of a fibrinous layer of exudate on a surface
Side 3: Where does this generally occur
Membranous or pseudomembranous exudates
Oral pharynx, trachea, airways, gastrointestinal tract
What are the two ways in which fibrinous exudate can resolve
Fibrinolysis or organization (conversion to scar tissue)
Etiologies of fibrinous exudate - where do they occur
Side 2: Fusobacterium necrophorum
Side 3: Infectious bovine rhinotracheitis virus (bovine herpesvirus 1)
Larynx of calves, "calf diphtheria"
Nasal cavity and trachea of calves
Etiologies of fibrinous exudate - where do they occur
Side 2: Infectious laryngotracheitis virus
Side 3: Salmonella
Larynx of trachea of chickens
Enteritis in pigs, calves, etc
Fibrinous exudate
Side 2: Positive attributes
Side 3: Neagtive attributes
Prevents spread of inflammation
Hinders inflammatory process by excluding oxygen, entrapping fluid and enzymes, and by exerting pressure on adjacent tissues
Compare and contrast fibrinous and fibrosis
Side 2: What is fibrinous
Side 3: What is fibrosis
A type of exudate that is broken down by fibrinolysis; from clotting system
May undergo 'organization' to form granulation (fibrous) tissue
Elastic and friable
Process of forming fibrous tissue "scar tissue"
Nonelastic, tough, difficult to tear or break down
What is mucoid exudate
Excess of mucus on a mucosal surface (GI and respiratory tracts) caused by mild irritation
What is mucopurulent exucate
Excess mucus infiltrated by neutrophils and desquamated epithelial cells on a mucosal surface
What is catarrhal exudate
Mucoid or mucopurulent exudate in GI tract which has entrapped ingesta
(may be used interchangeably with mucopurulent)
Side 2: What is hemorrhagic exudate
Side 3: When is it seen
Primarily escaped blood
Red to black
May combine with other exudate (serohemorrhagic, fibrinohemorrhagic)
Peracute to acute, usually severe inflammation
Occurs most often in ln, intestine, lung, urinary bladder
May be accompanied by other signs of inflammation
What is suppurative or purulent exudate
Diffuse or scattered accumulations of neutrophils in tissues
Side 2: What is pus
Side 3: What are the characteristics
liquid exudate composed of fluid dead or dying neutrophils and cell debris
Watery to creamy or pasty
yellowish, white, gray, greenish (eosinophils), rusty (RBCs)
Odorless or foul smelling (septic)
What is pyogenic exudate
Pus forming
Pyogenic bacteria - cause pus formation (E.coli, Klebsiella, pseudomonas, Staphylococcus
Side 2: What is an abcess
Side 3: What is a chronic abscess
a focal accumulation of pus in a tissue
Abscess enclosed by a fibrous capsule; the thicker the capsule, the more chronic the abscess
What is a fistula
Suppurative tracts that dissect along lines of least resistance from a cavity to a surface
Side 2: What is cellulitis
Side 3: What are some characteristics
Dissecting inflammation of subcutaneous tissue that may aggressively spread along fascial planes
Extensive tissue destruction and serous to seropurulent to suppurative exudate; +/- crepitation
Side 2: What is eosinophilic exudate
Side 3: What are some characteristics
Exudate in which large % of cells are eosinophils
Gross - Greenish yellow
Sites - Skin, mucosa, muscle
Etiologies - Allergic reactions, parasitic infections, salt poisoning of pigs
Side 2: What is nonsuppurative exudate
Side 3: What is it associated with
Exudate dominated by varying numbers of lymphocytes, plasma cells and macrophages
Associated with subacute to chronic inflammation and viral infections
What is follicular exudate
Conjunctivitis or pharyngitis - nodular accumulations of lymphocytes and plasma cells (lymphoid follicles)
What is lymphoplasmacytic exudate
More specific term than nonsuppurative