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35 Cards in this Set
- Front
- Back
- 3rd side (hint)
What are the 4 features which determine inflammatory classification
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Organ involved
Onset and course Architectural pattern Type of exudate |
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Side 2: What is the response to viruses
Side 3: What is the classification of inflammation |
Immune mediated responses
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mononuclear and nonsupppurative
(Lymphocytes and plasma cells ) |
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Side 2: What is the response to extracellular bacteria
Side 3: What is the classification of inflammation |
Phagocytosis and killing
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Suppurative
(Pus or purulent exudate) |
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What is the response to Intracellular bacteria, fungi
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Granulomatous respones
(epithelioid macrophages and giant cells) |
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Side 2: What are the 4 classifications of inflammatory response based on time
Side 3: What is the time frame for each stage |
Peracute, acute, subacute, chronic
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Peracute - rapid and severe
Acute - min. to 48 hours (exudative phase) Subacute - 3-7 days (exudative and early proliferative features) Chronic - >7 days (proliferative - fibroplasia) |
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Describe what is seen in focal/multifocal inflammation
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One or multiple foci of discrete inflammation in an organ
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Describe what is seen in locally extensive inflammation
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Major part but not all of an organ is inflamed
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Describe what is seen in diffuse inflammation
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All or nearly all of an organ or part inflamed
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Describe what is seen in interstitial inflammation
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Inflammation focused on interstitium of an organ (eg. kidney, lung)
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Describe what is seen in generalized inflammation
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Somewhat redundant with "diffuse" and less desirable. Diffuse inflammation of multiple organs or surfaces
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Side 2: Describe necrotic inflammation
Side 3: Where does it generally occur |
Inflammatory reaction in which substantial necrosis occurs acutely
Pale yellow to white or gray necrotic tissue separated from viable tissue by a sharp red inflammatory border Inflammed tissue separated from viable tissue with difficulty |
Intestine, mouth, liver
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What is erosion
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Necrosis or loss of mucosa that etends to but not through the basement membrane
(erosive stomatitis, enteritis) |
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Side 2: What is an ulcer
Side 3: what is the mechanism of action |
Necrosis or loss of mucosa that extends through the basement membrane
(Ulcerative stomatitis, enteritis, keratitis) |
enzymatic digestion of inflamed tissue leads to sloughing revealing an ulcer often bordered by a red rim of inflammation
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Side 2: What are the characteristics of serous exudate
Side 3: What is its purpose |
Clear, watery exudate (may be faintly yellow) with low protein content; mild inflammatory response
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Dilute toxins, contain antibodies
Good environment for bacterial growth |
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Side 2: What are the characteristics of fibrinous exudate
Side 3: How does the organ appear |
Yellowish, opaque, adherent, elastic, friable exudate; severe inflammatory response
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dull, granular, slightly frosted appearance
Fibrinous exudate peels easily from surfaces without bleeding |
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Side 2: What is the terminology for the formation of a fibrinous layer of exudate on a surface
Side 3: Where does this generally occur |
Membranous or pseudomembranous exudates
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Oral pharynx, trachea, airways, gastrointestinal tract
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What are the two ways in which fibrinous exudate can resolve
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Fibrinolysis or organization (conversion to scar tissue)
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Etiologies of fibrinous exudate - where do they occur
Side 2: Fusobacterium necrophorum Side 3: Infectious bovine rhinotracheitis virus (bovine herpesvirus 1) |
Larynx of calves, "calf diphtheria"
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Nasal cavity and trachea of calves
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Etiologies of fibrinous exudate - where do they occur
Side 2: Infectious laryngotracheitis virus Side 3: Salmonella |
Larynx of trachea of chickens
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Enteritis in pigs, calves, etc
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Fibrinous exudate
Side 2: Positive attributes Side 3: Neagtive attributes |
Prevents spread of inflammation
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Hinders inflammatory process by excluding oxygen, entrapping fluid and enzymes, and by exerting pressure on adjacent tissues
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Compare and contrast fibrinous and fibrosis
Side 2: What is fibrinous Side 3: What is fibrosis |
A type of exudate that is broken down by fibrinolysis; from clotting system
May undergo 'organization' to form granulation (fibrous) tissue Elastic and friable |
Process of forming fibrous tissue "scar tissue"
Nonelastic, tough, difficult to tear or break down |
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What is mucoid exudate
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Excess of mucus on a mucosal surface (GI and respiratory tracts) caused by mild irritation
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What is mucopurulent exucate
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Excess mucus infiltrated by neutrophils and desquamated epithelial cells on a mucosal surface
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What is catarrhal exudate
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Mucoid or mucopurulent exudate in GI tract which has entrapped ingesta
(may be used interchangeably with mucopurulent) |
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Side 2: What is hemorrhagic exudate
Side 3: When is it seen |
Primarily escaped blood
Red to black May combine with other exudate (serohemorrhagic, fibrinohemorrhagic) |
Peracute to acute, usually severe inflammation
Occurs most often in ln, intestine, lung, urinary bladder May be accompanied by other signs of inflammation |
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What is suppurative or purulent exudate
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Diffuse or scattered accumulations of neutrophils in tissues
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Side 2: What is pus
Side 3: What are the characteristics |
liquid exudate composed of fluid dead or dying neutrophils and cell debris
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Watery to creamy or pasty
yellowish, white, gray, greenish (eosinophils), rusty (RBCs) Odorless or foul smelling (septic) |
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What is pyogenic exudate
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Pus forming
Pyogenic bacteria - cause pus formation (E.coli, Klebsiella, pseudomonas, Staphylococcus |
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Side 2: What is an abcess
Side 3: What is a chronic abscess |
a focal accumulation of pus in a tissue
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Abscess enclosed by a fibrous capsule; the thicker the capsule, the more chronic the abscess
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What is a fistula
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Suppurative tracts that dissect along lines of least resistance from a cavity to a surface
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Side 2: What is cellulitis
Side 3: What are some characteristics |
Dissecting inflammation of subcutaneous tissue that may aggressively spread along fascial planes
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Extensive tissue destruction and serous to seropurulent to suppurative exudate; +/- crepitation
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Side 2: What is eosinophilic exudate
Side 3: What are some characteristics |
Exudate in which large % of cells are eosinophils
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Gross - Greenish yellow
Sites - Skin, mucosa, muscle Etiologies - Allergic reactions, parasitic infections, salt poisoning of pigs |
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Side 2: What is nonsuppurative exudate
Side 3: What is it associated with |
Exudate dominated by varying numbers of lymphocytes, plasma cells and macrophages
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Associated with subacute to chronic inflammation and viral infections
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What is follicular exudate
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Conjunctivitis or pharyngitis - nodular accumulations of lymphocytes and plasma cells (lymphoid follicles)
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What is lymphoplasmacytic exudate
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More specific term than nonsuppurative
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