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9 Cards in this Set
- Front
- Back
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describe the morphology of acute cellular rejection as seen in the interstitium, tubules and the vessels of the kidney.
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The interstitium has a mononuclear infiltrate, In the tubules there are mononuclear cells beneath the basement membrane and the blood vessels have mononuclear cells within or beneath an abnormal endothelium.
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darker and smaller
than those of the tubular epithelial cells. |
The nuclei of the
mononuclear cells are, in general, darker and smaller than those of the tubular epithelial cells |
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“pink circles
drawn around the borders of the tubules”. |
the basement
membranes of the tubules can be seen as “pink circles drawn around the borders of the tubules |
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readily identifiable in biopsies of renal allografts as dark blue
nuclei. |
The mononuclear cells
responsible for acute cellular rejection |
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one of the most
important morphologic features of acute cellular rejection. |
Tubulitis
Mononuclear cells are seen beneath the tubular basement membranes, socalled “tubulitis”. |
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mononuclear cells within the
intima, which is edematous and elevated. |
endotheliitis in Morphology: Acute Cellular Rejection
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introduced to describe nonspecific multifactorial morphologic changes in renal
allografts |
“chronic allograft nephropathy”
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Reductions in cross‐sectional diameter due to
(intimal) thickening describes what |
the vessels of chronic allograft nephropathy
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describe the Morphology: Chronic Allograft Nephropathy
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Interstitial fibrosis, tubular atrophy, and blood vessels with reductions in cross sectional diameter due to intimal thickening.
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