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6 Cards in this Set
- Front
- Back
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Mutation of signal transduction protein K-RAS H-RAS N-RAS |
- colon ca, lung ca, pancreatic ca - bladder ca, kidney tumors - melanoma |
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Nuclear transcription factor mutation C-MYC N-MYC L-MYC |
Burkitt lymphoma Neuroblastoma Small cell ca of lung |
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Metastatic signature genes snail & twist Ezrin MIR 10 b |
Breast ca Rhabdo, osteosarcoma |
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Molecular scissors Most radiosensitive phase in cell cycle Most radioresistant phase most radiosensitive cell Most radioresistant cell |
- zinc finger nuclease, Meganuclease, TALEN, CRiSPR - G2M -S - lymphocyte - platelet |
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Marfan syn Diagnosis criteria Treatment Biopsy Elastin stain |
- Revised Ghent criteria Family history, signs and symptoms, fibrillin 1 gene mutation - TGF BETA Blocker - losartan - Cystic medial degeneration - Von gieon |
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Gaucher disease Gaucher cell stains Pseudogaucher |
PAS+, Oil red O+, Pearl Stain+ - PAS -ve, CML |
