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224 Cards in this Set

  • Front
  • Back
The generalized OPALESCENCE of the buccal mucosa is most likely...
Leukodema
Leukodema is caused by a significant intercellular edema in which layer of the stratified epithelium?
Prickle Cell Layer
Does leukodema require tx?
No, variant of normal
A bony, asymptomatic area found on the midline of the hard palate that appears radiopaque on a radiograph?
Torus palatinus
Which of the following cysts would create difficulty when swallowing?

-Dentigerous
-Thyroglossal
-Nasopalatine
-Mucocele
-Residual
Thyroglossal
Which disease may have oral characteristics similar to those in necrotizing ulcerative gingivitis (NUG)
Leukemia
A ranula is typically found...
Floor of the Mouth
A definitive dental dx of soft tissue oral cancer is made by:

-complete radiographs
-PAN
-scalpel biopsy
-exfoliative cytology
-brush biopsy
Scalpel Biopsy
Primordial cysts are most often found radiographically...
IN PLACE OF 3rd molar or posterior to an erupted 3rd molar

**tooth was never present, in place of tooth**
The usual location of periapical cemento-osseous dysplasia (cementoma) is...
ANT Mandible
A slightly raised, noncoated, red, glossy, rectangular area in the midline of the tongue has been present as long as pt can remember...thought to be assoc w/Candida albicans
Median Rhomboid Glossitis
What two viruses are caused by the varicella-zoster virus
1. Herpes Zoster (Shingles)

2. Chickenpox
40yr old pt w/lesion on her lips. Lesion appears as several discrete vesicles, some are ulcerated. She says she gets a sore like this right before she gets a cold.
Herpes Labialis
-sessily or pedunculated (rare)
-grows rapidly first to a max size, then stops
-typically assoc w/pregnancy
Pyogenic Granuloma
What cyst has the potential to develop into an ameloblastoma?
Primordial Cyst
Palatal condition common in elderly w/dentures, chronic irritation

-cobblestone appearance(erythematous papillary projections)

-vault of palate
Papillary Hyperplasia
Lesion found on the buccal mucosa of 30yr old white, woman. Pink, well-defined, SOFT to palpitation, consists of collagenous fibers, fibroblasts, fibrocytes. NO fat cells or bone
Fibroma
Radiolucent lesion assoc w/a cyst, cyst. Histology report shows salivary gland tissue in the cyst
Static Bone Cyst
Well-defined, yellowish blisterlike formation, rare, benign neoplasm, predominance of fat cell
Lipoma
A tooth involved w/a cyst is discovered to be nonvital pulp test
Radicular Cyst
What is the main characteristic for pemphigus vulgaris?
Nikolsky's Sign
35yr old woman Assessment reveals an inflamed, palpable, benign tumor in the anterior of the palate, lingual to the max incisors. The tumor arises from deeper tissue originating from periodontal ligament, infiltrates bone but isn't metastisized.

-caused by local irritant/trauma
-PDL origin
-Gingiva or Alveolar Mucosa
-females 2x more
Peripheral Giant Cell Granuloma
Severe hypersensitivity reaction w/lips and tongue
-bulls-eye lesions on skin
-blood crusted lips
Erythema Multiforme
What cyst forms is the result of extracting a tooth w/out the cystic sac

-Well-defined radiolucent area
-Round or Oval shaped
Residual Cyst
-White cauliflower-like
-similar to a wart
-long, finger-like projections of epithelium
Papilloma
What makes Behcet's syndrome different from recurrent ulcerative stomatitis
Triad effect
(eyes, mouth, genitals)
What is the causative agent of Herpangina?
Coxsackievirus
True or False

Palatal tori occur more frequently in woman.
True
What epithelial layer are melanocytes found in?
Basal Cell layer
-mass in midline of the dorsum of the tongue posterior to the circumvallate papilla made up of thyroid tissue

-common in women assoc w/hormonal changes
Lingual Thyroid Nodule
What papilla does Median Rhomboid Glossitis effect
Filiform Papilla
What are the etiologic factors that affect Geographic Tongue
Idiopathic
Stress
Genetic (possible)
This increase in the amt of blood in the area is called active ______.
Causes erythema and heat.
Hyperemia
What is the process where the white blood cells are forced to adhere to endothelial cells, goes to sides of margins of blood vessels
Margination
What cells produce antibodies?
Plasma Cells
What is the process when endothelial cells become sticky, WBC adhere to endothelium
Pavementing
What cells are the link between the inflammatory and immune responses?
Macrophages
This is the production of sequential cascade of plasma proteins present in blood in an inactivated form.
Complement System
What is the body's first line of defense and assoc w/ACUTE inflammation
Neutrophil
What WBC is assoc w/CHRONIC inflammation
Macrophage
What is the formation of pus called?
Suppuration
5 Cardinal signs of Inflammation
1. Redness
2. Swelling
3. Heat
4. Pain
5. Loss of normal tissue fx
This is the increase in the NUMBER of cells
Hyperplasia
This is the increase in SIZE of cells/tissue
Hypertrophy
-epithelium blanched/whitened
-will eventually separate and slough leaving an ulcer
-a burn
Aspirin burn
-red/inflam of palate
-becomes keratinized w/red dots
Nicotine Stomatitis
Etiology: cumulative sun exposure

-border of lip is pale pink
-cracking present
-LOWER lip more severely affected
Solar Cheilitis
Etiology: salivary gland duct is severed mucous secretion spills in adjacent tissue

-blue in color if near to surface
-normal color if deeper
-solitary
-compressible
-not a true cyst
Mucocele
Etiology: mucocele that forms unilaterally on the floor of the mouth

-"frog's" belly
Ranula
Etiology: ill-fitting denture

-elongated folds
-dense, fibrous CT w/stratified squamous epithelium
-usually MANDIBLE
Denture-induced Fibrous Hyperplasia
What 3 meds are known to cause gingival hyperplasia
Cyclosporine (Immunosuppressive)

Dilantin (Epilepsy)

Procardia (hypertension/angina)
Etiology: obstruction of salivary gland duct or infection

-painful
-swelling of major salivary gland
Sialadentitis
Etiology: proliferation of chronically inflamed pulp tissue

-children/young adults
-overproduction of granulation tissue that herniates into oral cavity
Chronic Hyperplastic Pulpitis
(Pulp Polyp)
What is the only way to tell a Periapical Granuloma from a Radicular Cyst?
Biopsy
Etiology: localized mass of chronic, granulated tissue assoc w/a non-vital tooth

-mass w/lymphocytes, plasma cells, macrophages, and epithelial rests of Malassez

-if left untreated will turn into a Radicular Cyst
Periapical Granuloma
Etiology: true cyst, develops from pre-existing periapical granulomas
males 30-60yrs

*MOST COMMON cyst in oral cavity*
-fluid filled sac lined by stratified squamous epithelium
-root of non-vital tooth
Radicular Cyst
Etiology: change in bone near apex, MAND 1st MOLAR usually affected

**RADIOPAQUE**
Focal Sclerosing Osteomyelitis
What part of the antibody does the antigen attach to?
Fab
What part of the antibody does the macrophage attach to?

What does it help facilitate
Fc

Ingestion
What type of immunity doesn't depend on antibodies
Cell Mediated Immunity
What immunoglobulin acts as an opsonin?

-most numerous
-enhances phaGocytosis
IgG
What immunoglobulin activates the coMpliMent system?
IgM
What immunoglobulin prevents bacterial Adherence?
IgA
What immunoglobulin binDs to surface of B lymphocytes and triggers stimulation
IgD
What immunoglobulin releases histamines
IgE
What cell presents antigen to T cell?
Macrophage
What is the most important T cell, increase fx of B cells, enhance antibody response
T helper cell
what stimulates WBC growth b/c initial response wasn't good enough, antigens are multiplying
Interleukin
What cell releases lymphokines which then releases interleukins and interferons?
T cell
What cell activates macrophages to phagocytize better?
Interferon
What immunity involves plasma cells?
Hummoral Immunity
What immunoglobulin is the fist to respond?
IgG
In the complement cascade, what are the major components that lead to membrane lysis
C1-C9
What type of hypersensitivity is life threatening?

-asthma
-anaphylactic shock
Type I Hypersensitivity
What type of hypersensitivity involves Rh incompatibility and is dependent upon the complement system?
Type II Hypersensivity
What type of hypersensitivity is acute inflammatory response and complement activation and the intensity of the reaction increases.

i.e. autoimmune disease
Type III Hypersensitivity
What type of hypersensitivity involves cell-mediated response instead of humoral and cause T lymphocytes damage to self

-contact dermatitis
-poison ivy

-ORGAN TRANSPLANT REJECTION
Type IV Hypersensitivity
What type of resorption occurs in the crown and usually involves one tooth
Internal Tooth Resorption
What type of resorption is commonly assoc w/ortho?
-from the outside surface
External Tooth Resporption
What do apthous ulcers begin as?
Macules
-white,yellowish fibrin surrounded by erythematous halo
-MOVEABLE MUCOSA only
-very painful
-anteriorly more common
Minor Apthous Ulcers
-ulcer that lasts longer
-results in greyish-pink scar
-POSTERIOR part of mouth
Major Apthous Ulcer
Etiology: idiopathic, increased level of stress

-common location on buccal mucosa
-tx only when painful
Lichen Planus
What is the name of the slender white lines assoc w/lichen planus?
Wickham's Striae
What condition affects salivary and lacrimal glands (XEROSTOMIA)

-very dry mouth (loss of filiform/fungiform papilla)
-candidiasis
Sjogren's Syndrome
Etiology: autoantibodies that react against epithelial cell attachment. Jewish women 40-50

-Painful Ulcers-->vesicles/bullae

-Bullae rupture leaving a grayish membrane

-involves Tzanck cells

-INTRAepithelial (above the basal cell layer)
Pemphigus Vulgaris
-Bullae are less fragile
-bullae are SUBepithelial
-basement membrane separates from CT
Cicatricial Pemhigoid
Etiology: primary lung infection, granulomatous disease

-ulcer in middle of the tongue
Tuberculosis
What drug is commonly used to treat tb
Isoniazid
With pemphigus vulgaris do oral or skin lesions occur first
Oral
What is the primary stage of Syphilis, highly infectious
Chancre
What is the tertiary stage of Syphilis
Gumma, hole in the palate
What is the most common form of candidiasis
Chronic Atrophic (denture stomatitis)

usually no pain/burning
What type of Candidiasis CAN'T be wiped away and what is it assoc with
Chronic Hyperplastic

HIV
Etiology: WHITE papillary caused by HPV

-LIPS most common site
Verruca Vulgaris (common wart)
Etiology: PINK, bulbous papillary masses (sexual contact)

-Very contagious
-tongue, buccal mucosa, palate, gingiva, alveolar ridge
Condyloma Acuminatum (venereal wart)
Etiology: usually in trigeminal ganglion
-recurrent lesion
-vermillion border (most common site)

What are other names is it known as
Recurrent Herpes

aka: Herpes Labialis
-cold sore
Pain, burning, tingling are all what type of symptoms for Herpes Labialis (recurrent herpes)
Prodromal Symptoms
painful HSV infection of fingers, can be primary or recurrent, occular herpes
Herpetic Whitlow
Etiology: Varicella zoster, thoracic area more common, follows the opthalmic division of trigeminal nerve

-extremely painful
Herpes Zoster (Shingles)
What two conditions are caused by Varicella zoster
Herpes Zoster (Shingles)

Chickenpox
Etiology: coxsackievirus, more common in the SUMMER months

-bilateral vesicles
-fever, malaise, sore throat, dysphagia, erythematous pharyngitis
Herpangina
Etiology: Paramyxovirus, highly contagious

-skin rash/Koplik's spots
Rubeola (Measles)
Etiology: paramyxovirus

-rash on face, extremely dangerous during 1st trimester of pregnancy
Rubella (German Measles)
Etiology: small mass of thyroid tissue located on the tongue

-immature or mature thyroid tissue
Ectopic Lingual Thyroid Nodule
What cyst is always assoc w/impacted or unerupted tooth

-most common cyst
-assoc w/ameloblastoma
Dentigerous
Etiology: located in place of the 3rd molar or posterior to an erupted 3rd molar

-can become an ameloblastoma
AGGRESSIVE
Primordial Cyst
Etiology: unique histologic appearance and high rate of recurrence

lining of cyst produces keratin

Well-defined multiocular radiolucency or unocular in the 3rd molar region
Odontogenic Keratocyst
Etiology: can be found in incisive papilla, located in the nasopalatine duct

-Heart-shaped radiolucency
Nasopalatine Cyst
Etiology: located POSTERIOR to incisive papilla in the midline of the hard palate

well-defined UNIocular

(just a nasopalatine cyst that moved posteriorly)
Median Palatine Cyst
What type of candidiasis is like cottage cheese accompanied by burning and metallic taste
Pseudomembranous
Etiology: between roots of max lateral and canine

pear-shaped radiolucency
Globulomaxillary Cyst
Etiology: originates from lower portion of nasolacrimal duct. Near MAX CANINE
Nasolabial Cyst
Etiology: originates from hair follicle
Epidermal Cyst
-above or below mylohyoid muscle
-"dough boy"
-very soft
Dermoid Cyst
Etiology: pseudocyst (lining of cyst is CT)

-well defined uniocular/multiocular w/scalloping around roots

-assoc w/punch to the face
Simple Bone Cyst
-honeycomb/soap-bubble appearance
Aneurysmal Bone Cyst
Etiology: absence of one or more teeth

what are the three most common teeth missing (in order from most common)
Hypodontia

1. 3rd molars

2. MAX canine

3. MAN 2nd Premolar
Are supernumerary teeth more common in the maxilla or mandible
maxilla, 8x more common
What is the most common type of supernumerary tooth?
Mesiodens
Does a distomolar commonly erupt
No
Etiology: one or more teeth smaller than normal

-assoc w/dwarfism
Microdontia
What is the most common tooth assoc w/microdontia
Peg Lateral (max)
Etiology: tooth germ attempts to split

-notched incisal edge
-1 Root; 2 Crowns
Gemination
Etiology: union of two normally separated adjacent tooth germs

-2 Roots; 1 Crown
Fusion
What dentition is fusion more common in and does it happen anterior or posterior
-Primary

-Anterior
Etiology: roots joined by cementum.

-Maxillary Molars

-CAN'T be observed clinically
Concrescence
Etiology: abnormal curve or angle in root or crown. Trauma to tooth germ during root formation
Dilaceration
Where is the most common place for an enamel pearl
Max Molars
Etiology: accessory cusp in cingulum area of max/man incisor

-normal enamel, dentin, and PULP HORN
Talon Cusp
Etiology: elongated, large pulp chambers and short roots
Taurodontism
"tooth within a tooth"

Max Left Lateral Incisor most commonly affected

-commonly decays
Dens in Dente
What tooth is the most common single rooted tooth to possible have two roots?
Mandibular Canine
Etiology: disturbance/damage to sensitive ameloblasts during enamel matrix formation
Enamel Hypoplasia
What type of hypoplasia effects a single tooth typically caused by decay from a primary tooth?
Turner's Tooth
What type of hypoplasia is assoc w/syphilis and causes incisors to be shaped like screwdrivers
Hutchinson's Incisors
Localized, chalky white spot on the middle third of smooth crowns
Enamel Hypocalcification
Etiology: Rh incompatability, or ingenstion of substance (tetracycline)

-yellow/green staining
Endogenous (Intrinsic) Stain
Very thin enamel, anterior maxilla is more common
Regional Odontodysplasia (ghost teeth)
What is the most common position for impacted 3rd molars
Mesioangular
Etiology: primary teeth in which bone has fused to the cementum and dentin preventing primary tooth exfoliation
Ankylosed Teeth
What is assoc w/permanent and avulsed teeth
Ankylosis
-open, painless lesions that don't resolve in 2wks

-wart-like growths

-persistent, scaly red patches w/irregular borders

-elevated growths w/rough surfaces and a central depression

-in the mouth
Squamous Cell Carcinoma
-Open, bleeding crusted lesions, don't heal w/in several wks

-reddish, raised or itchy areas of skin

-shiny pink, red, white or translucent nodules

-pink or red bordered lesions w/crusted centers

-involved w/skin
Basal Cell Carcinoma
What are the 5 parts of melanoma screening
Asymmetry: if lesion's cut in half, the halve don't look the same

Border: irregular

Color: different shades, multi

Diameter: anything bigger then a pencil eraser

Evolving: change in color, size, texture

ABCDE
What types of tumors are pleomorphic
Malignant Tumors
Etiology: tobacco use and drinking, HPV

-males, blacks, >45yrs old

-malignant tumor of squamous epithelium
Squamous Cell Carcinoma
Is oral cancer genetically tied?
No
What is the name for cell "suicide"
Apoptosis
What are the most common areas for squamous cell carcinoma (in order from most common)
1. floor of mouth
2. ventrolateral surface of tongue
3. soft palate
4. tonsillar pillars
5. retromolar areas
Advanced lesions, fixed ulcer w/raised ROLLED BORDERS
Squamous Cell Carcinoma
white, plaque-like lesion CAN'T be rubbed off and can't be diagnosed as a specific disease

Etiology: idiopathic, local irritation, tobacco, C albicans infections
Leukoplakia
Leukoplakia is commonly found in what two places?
(malignant or premalignant)

more common than erythroplakia
1. Floor of Mouth
2. Tongue
What is more aggressive and is more likely to be squamous cell carcinoma
Erythroplakia
Etiology: variant of squamous cell carcinoma, "good cancer," doesn't metastisize, tobacco use

-males >55
-slow growing
-pebbly white/red surface at labial commissures
-intact basement membrane
-resembles papilloma
Verrucous Carcinoma
Etiology: sun exposure. Malignant tumor of squamous epithelium that occurs on skin NOT in oral cavity. Strong genetic tie, blue/green eyes, red/blond hair

-non-healing ulcer of SKIN w/rolled borders

-proliferation of basal cells
Basal Cell Carcinoma
Etiology: benign salivary gland tumor. MOST COMMON salivary gland neoplasm

-painless
-NON-ulcerated
-35% recurrence
Pleomorphic Adenoma
What is the most common site for pleomorphic adenoma?
Palate- intraoral

Parotid Gland- extraoral
Etiology: malignant salivary gland tumor

-ULCERATED
-similar to SWISS CHEESE
-tends to surround nerves

parasthesia and bone destruction
Adenoid Cystic Carcinoma
Etiology: malignant salivary gland tumor, MUCOUS cells and squamous-like epithelial cells

Major=Parotid Gland

Minor=Palate

*transformed epithelial lining of a DENTIGEROUS CYST (impacted/unerupted tooth)
Mucoepidermoid Carcinoma
Etiology: benign, slow-growing but AGGRESSIVE epithelial odontogenic tumor

-may result from a dentigerous cyst left in mouth

-80% in mandible; molar/ramus area

-can be lethal in maxilla

-HONEYCOMBED appearance, multiocular

-COMMON RECURRENCE
Ameloblastoma
What type of tumor originates from tooth-forming tissues; composed of epithelium only, mesenchymal tissue, or a mix of both
Odontogenic Tumor
What type of ameloblastoma occurs in the GINGIVA, doesn't involve bone or recur
Peripheral Ameloblastoma
Etiology: benign, originating from mesechymal tissues of the tooth germ, dental papilla

10-29yrs old

-cause tooth displacement/root resorption

-MULTIocular, poorly defined margins
(honeycombed appearance)
Odontogenic Myxoma
well circumscribed tumor composed of fibrous CT and round globular calcification resembling CEMENTUM
Cementifying Fibroma
calcifications that resemble bone trabeculae
Ossifying fibroma
GLOBULAR calcifications and bone trabeculae
Cemento-ossifying fibroma
radioPAQUE

Tumors that have well-defined borders, radiolucent to radiopaque depending on calcified tissue
Cementifying and Ossifying Fibromas
Etiology: cementum producing lesion that's fused to the root.

-young men

-well defined radioPAQUE mass that is CONTINUOUS w/roots, surrounded by RADIOLUCENT HALO
Benign Cementoblastoma
Etiology: benign odontogenic tumor containing tissue similar to the dental papilla

-men <20
-common in MAND PREMOLAR/MOLAR region

-well/poorly demarcated uniocular/multiocular radiolucency
Ameloblastic Fibroma
Etiology: idiopathic

MOST COMMON odontogenic tumors

-failure of a permanent tooth to erupt
Odontoma
What are the 2 types of Odontomas? and where are they located

-composed of mature enamel, dentin, cementum, and pulp
Compound: Anterior Max

Complex: Post Mandible
What is assoc w/impacted, unerupted teeth, or odontogenic cysts and tumors.

-usually located BETWEEN the ROOTS of teeth
Odontoma
What type of odontoma is a cluster of numerous small teeth surrounded by a radiolucent halo?
Compound
What type of odontoma is a radiopaque mass surrounded by a thin radiolucent halo
Complex
benign tumor of mature fat cells

tongue, buccal mucosa, vestibule, and gingiva
Lipoma
Etiology: benign tumors of Schwann cells

-most common location TONGUE
Neurofibroma
Etiology: benign tumor either neural or primitive mesenchymal cell origin

-painless
-NONulcerated NODULE
-TONGUE, buccal mucosa
-female adults
Granular Cell Tumor
Etiology: benign growth of capillaries, affect gingiva causing hemorrhage

-deep red/blue color
-girls
-blanch upon pressure
-spontaneous remission
Hermangioma
What is the most common location for a hermangioma?
Tongue
What are the two types of hermangiomas and what do they involve?
Capillary: contains SMALL capillaries

Cavernous: LARGE blood vessels
Etiology: BENIGN tumor of melanocytes, usually extraoral

-brown macules or papules commonly located on hard palate and buccal mucosa
Melanocytic Nevus
Are all melanomas malignant?
Yes
Etiology: malignant tumor of melanocytes

-blistering sunburn
-hard palate and max gingiva
-rare in mouth
-Very Aggressive
-doesn't respond to chemo
Malignant Melanoma
Etiology: malignant growth of plasma cells which cause destructive bone lesions

-Fatal
-men>40
-mandible
-RADIOLUCENT LESIONS in SKULL
Multiple Myeloma
Etiology: idiopathic, teeth are VITAL

-black, women >30
-menopause

-disordered production of cementum and bone

-changes from radiolucent to radiopaque as it ages
Periapical Cemento-osseous Dysplasia
Etiology: idiopathic

Gritty pieces of hard and soft tissue

-posterior mandible
-white, women 30-50

May progress into florid cemento-osseous dysplasia
Focal Cemento-Osseous Dysplasia
Etiology: idiopathic

-black, women >40
-more extensive than periapical/focal cemento-osseous dysplasia

-MULTIPLE QUADS

-large posterior radiopaque mass, no radiolucent phase
Florid Cemento-osseous Dysplasia
Etiology: Viral. Chronic metabolic bone disease w/resorption, osteoblastic repair and remin

-COTTON WOOL appearance
-Maxilla
-enlargement of bone
Paget Disease
What type and name of bisphosphonate is commonly responsible for Osteonecrosis of the Jaw
IV: zoledronate (Zometa)
what oral bisphophonates are sometimes known to cause ONJ (osteonecrosis of the jaw)
alendronate (Fosamax)
risedronate (Actenol or Boniva)
How long after dental tx does ONJ typically occur
2 months
If a ct is on IV bisphosphonate what special instructions are there?
-AVOID extraction of M3 teeth
-if extraction needed, pre-med
-CHX rinse 2x a day for 2 months post surgery
If a ct has ONJ what are the special instructions
-Pre-med
-reduce sharp/rough areas of bone
-CHX 2x/day
-ONJ site should be debrided every 2-3wks
-Hyperbaric oxygen therapy
What form of oral cancer detection uses a chemiluminescent light source and a blue phenothiazine dye to mark lesions
ViziLite Plus w/TBlue
What type of oral cancer detection is computer assisted method of oral brush biopsy that allows dentists to test the common small white and red lesions that appear in the mouth
Oral CDx Brush test
What type of oral cancer detection emits a blue light into the oral cavity which excites the tissue from the epithelium's surface to the underlying CT causing it to FLUORESCE
VELscope
What type of oral cancer detection uses an LED light source and a mirror
Orascoptic DK
Etiology: nondisjunction assoc w/late maternal age

MOST FREQUENT of trisomies

Oglidontia: few teeth
Trisomy 21
Etiology: nondisjunction of X chromosome

-webbing of neck
Turner's Syndrome
Etiology: bandlike increase of several mm in width

-follows normal ging contour

*assoc only w/genetics

-perakeratosis where not normally found (retromolar pad area)
Gingival Hyperkeratosis
Etiology: autosomal-dominant, may also be related to number of trisomies

-gingival hypertrophy
-firm tissue w/a granular corrugated surface
-pale in color
-may cause protrusion of lip
Gingival Fibromatosis
Etiology: autosomal-dominant, males, begins at birth or early childhood

-Bilateral facial swelling
-usually mandible
-primary teeth lost by 3yrs old
-remission occurs 8-10yrs old

"Soap Bubble", MULTIocular appearance in ramus/molar/premolar area
Cherubism
Etiology: autosomal-recessive

-fusion of anterior portion of max ging to upper lip from canine to canine

-lack of max vestibule

-central incisors NOT present

-conical shaped and enamel hypoplasia

>50% of newborns have NATAL TEETH
Chondroectodermal Dysplasia
Etiology: autosomal-dominant or spontaneous mutation

-aplasia or hypoplasia of clavicles (allows shoulders to touch midline)

-MANY SUPERNUMERARY w/a possible THIRD DENTITION
Cleidocranial Dysplasia
What genetic disorder has a "fish"like mouth, high cleft palate in 30% of patients

-Hypoplastic Mandible
Mandibulofacial Dysostosis
What genetic disorder has numerous pin-point and spider-like telangiectases of lips, eyelids, nose, and scalp

Prominent on TIP and ANTERIOR DORSUM OF TONGUE
Hereditary Hemorrhagic Telangiectasia
Genetic disorder w/multiple neurofibromas, papules of various sizes located on eyelids and oral cavity

Cafe'-au-lait (coffee w/milk) skin pigmentation seen w/90% of patients
Neurofibromatosis of von Recklinghausen
Inherited disorder: small areas of CHIPPED enamel or no enamel covering dentin

*RARELY get CARIES
Amelogenesis Imperfecta
What type of inherited disease produces GRAY to BLUISH-BROWN teeth?

-more severe in PRIMARY dentition

-NO pulp chambers or root canals are visible

-THIN, SHORT ROOTS w/pariapical radiolucencies
Dentinogenesis Imperfecta
Etiology: autosomal-dominant

-normal crowns, ABNORMAL ROOTS

-short roots= PREMATURE LOSS
Dentin Dysplasia
Etiology: X-linked recessive and autosomal RECESSIVE

-HYPODONTIA

-Hyptrichosis (abnormal deficiency of hair)

-Hyphidrosis: diminished perspiration due to lack of sweat glands

-frontal bossing, saddle nose, protruding hair, thin/dry skin
Hypohidrotic Ectodermal Dysplasia
Etiology: Genetic CT disorder. Chemical make up of CT isn't normal=many structures aren't as stiff as they're supposed to be

-pt often TALL and THIN

-HIGH/ARCHED palate

-crowded teeth

-SMALL MANDIBLE

**PRE-MED (mvp) susceptible to endocarditis
Marfan Syndrome
What systemic disease has an increase of growth hormone during adulthood

-hand and feet enlargement
-CLASS III occlusion
-prognathic
-macroglossia
Acromegaly (Hyperpituitarism)
Etiology: decrease production of adrenal steroids

-pituitary gland secretes ACTH, which stimulates melanocytes
Addison Disease
These are oral manifestations of what disease:

-Candidiasis
-Hairy Leukoplakia
-Herpes Simplex
-Linear Gingival Erythema
-NUG
-NUP
-Kaposi's Sarcoma
-Oral Warts
-Herpes Zoster (shingles)
-Apthous Ulcers (major and minor)
-Non-Hodgkin's Lymphoma
-Salivary Gland Disease
HIV Infection
What is the most common EARLY oral manifestation of HIV and what is it a strong predictor of?
Candidiasis (larger area)

strong predictor of NUG
What oral manifestation is ALWAYS assoc w/HIV
Hairy Leukoplakia
Once hairy leukoplakia is discovered, how long does the pt have to live
4 years
What is used to treat Herpes Zoster (shingles) in HIV patients
Acyclovir

HIGH dose: 2400-3200mg/day
HIV patients w/NUP should use what type of rinse prior to debridement for pain control
Betadine (Providone Iodine)
What other meds can be used to control acute episodes w/pain for HIV patients w/NUP
Flagyl (metronidazole)
Augmentin

MT visits 2-3mos after acute phase is controlled
What oral manifestation in an HIV-positive patient ESTABLISHES DX of AIDS

HSV-8 is the cause of this neoplasm

-reddish/purple, flat/raised, single/multiple lesions

-PALATE
-facial ging of 8&9
Kaposi's Syndrome
Xerostomia in an HIV pt is typically caused by
Parotid Gland Enlargement