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23 Cards in this Set
- Front
- Back
diffusely circumscribed non-caseating granulomata
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Sarcoidosis - 10x more frequently in African Americans.... more in men!
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Mikulicz syndrome in sarcoidosis includes bilateral sarcoidosis of which glands?
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parotid, sublingual, submaxillary
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characteristic of Goodpasture
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Ab against BM (basement membrane) of lung and kidney (-crescentic glomerulonephritis)
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c-myc oncogene
males cigarette smoking |
Squamous cell carcinoma
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K-ras
females non-smoking mucin Carcinoembryonic antigen (CEA) |
Adenocarcinoma
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most aggressive form of lung cancer?
oat cell (scanty citoplasm, dark dark dark nucleus...many on slide) |
small cell carcinoma (inoperable->chemo)
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exophthalmos
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bulging eyes
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anhidrosis
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inability to tolerate heat (+exophthalmos, mitosis (pinned) and ptosis => Honer syndrome)
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Malignant Mesothelioma vs benign
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malignant is with massive pleural effusion (dull percussion)
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most dangerous size for particles in Pneumoconiosis
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1-5 micrometers because they can reach terminal airway alveoli
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NB no tuberculosis prophylaxis for pnt over 30 y.o. b/c hepatotoxic. Younger? go ahead!
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only primary tuberculosis has Ghon complex
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what's Ghon complex made of?
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a parenchimal subpleural lesion and enlarged caseating lymph nodes
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secondary tuberculosis is more damaging than primary. contains
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Langhans multinucleated giant cells in scars and tubercles
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lobar pneumonia
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red hepatization (Strep pneumo, Klebs., H.ifluenzae, Staph)
if mucoid secretions? Klebs is the agent (capsule!!!!!!!) |
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Bronchiectasis
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permanent dilation of bronchi (usu BASAL lobels) foul smelling bloody sputum
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Cruschman plugs and Charcott-Leyden crystals
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in asthma
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Drug induced asthma
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mostly aspirin (a woman in chronic pain taking OTC meds)
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Atopic asthma
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allergic-> eosinophilic IgE
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non-atopic asthma
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viral mostly-> irritation ->bronchoconstriction
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senile emphysema
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NO associated septal destruction
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alpha 1 antitrypsin is the enzyme that fights elastase
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nb
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panacinar emphysema
centriacinar |
basal lower lobes
upper lobers |
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in ARDS
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patchy atelectasis due to loss of surfactant, hyaline membrane. Dx is refractory to oxygen therapy
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