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12 Cards in this Set
- Front
- Back
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Parathyroid Gland |
Chief cells |
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Chief Cells |
Regulates serum free calcium via PTH |
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Parathyroid Hormone |
Increases bone osteoclast activity Increases small bowel absorption of Ca and phosphate Increases renal calcium reabsorption |
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Parathyroid Glands |
Increased serum ionized calcium levels Provide negative feedback to dec PTH secretion |
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Primary Hyperparathyroidism |
Excess PTH due to to a disorder of the parathyroid gland itself |
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Parathyroid Adenoma |
Most common cause of primary hyperparathyroidism |
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Parathyroid Adenoma |
Benign neoplasm Usually involves one gland Asymptomatic hypercalcemia, inc PTH Inc PTH, Inc Ca, Dec PO4, Inc urinary cAMP, Inc ALP Treatment, surgical removal of affected gland |
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Secondary Hyperparathyroidism |
Excess production of PTH due to a disease process extrinsic to the parathyroid gland |
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Secondary Hyperparathyroidism |
Most common cause is chronic renal failure Inc PTH, Dec Ca, Inc PO4, Inc ALP |
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Hypoparathyroidism |
Low PTH Causes include autoimmune damage to the parathyroids, surgical excision, DiGeorge syndrome |
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Hypoparathyroidism |
Presents with symptoms related to low calcium Numbness and tingling Muscle spasms (tetany) Dec PTH, Dec Ca |
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Pseudohypoparathyroidism |
Due to end organ resistance to PTH Autosomal dominant Associated with short stature and short 4th and 5th digits Hypocalcemia with Inc PTH |
