Pathology Cell Adaptaion, Injury And Death From Dr. Simms

Front 1

hyperplasia - definition

friction hyperplasia

Back 1

the presene of increased number of cells in an organ

constant friction and pressure on skin results in thickening of the epidermis and callus formation

Front 2

Atypical Aveolar Hyperplasia

Back 2

coinsidered a premalignant lesion for carcinomas of lung
presence of p53 (aka TP53) activity encoded at 17q13

Front 3

endommetrial Hyperplasia
causes

Back 3

abnormal proliferation of endometrial glands of irregular size and shapw w/ increase in gland/stroma

high amounts of estrogen over a prolonged time, also some estrogen antagonists

Front 4

hypertrophy

Back 4

number of cells in an organ stay the same but a number of individual cells get larger

Front 5

Hypoplasia

Back 5

a decrease in cell numer w/o a decrease in cell size

Front 6

atrophy

Back 6

the number of cells remain the same but there is a decrease in cell size

Front 7

difference in involution or atrophy, and agenesis

Back 7

agenesis is a failure of development of the embryonal tissues that precede and organ resulting in complete absence of the organ. where atropy or involution requires that the organ had achieved normal developmental size prior to involuting to becoming atrophic

Front 8

aplasia

Back 8

the embryonal cell mass develops and is visibly present tbut does not further differentiat into a mature functional organ

Front 9

dysgenesis

Back 9

cell mass undergoes develoment, but the microscopic architecture of the organ is abnormal and often has a mixture of immature and mature elements

Front 10

dysplasia

Back 10

an ambiguous term as it can be taken to relate ot either developmental abnormalities or premalignancy changes.