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28 Cards in this Set

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  • Back
inflammation
a reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues
edema
an increase in extravascular fluid
effusion
excess fluid in the cavities of the body
transudate
edema fluid with a loss of protein content
exudate
edema fluid with a high protein content
serous
effusion/exudate with absence of cellular response components
serosanguinous
effusion/exudate with erythrocytes
fibrinous
exudate with large amounts of fibrin from activation of the coagulation system
purulent
effusion/exudate with prominent cellular components
suppurative
purulent exudate is accompanied by significant liquefactive necrosis
vasoactive mediators
cellular components that influence responses of the microvasculature to injury
platelet
a peripheral blood component arising from bone marrow that plays a primary role in the initiation and regulation of clot formation
mast cell
cell within connective tissue containing receptors for IgE; when stimulated by an antigen, a variety of inflammatory mediators are secreted into extracellular tissues
complement system
a group of 20 plasma proteins that are a source of vasoactive mediators and play an important role in host defense against bacterial infection
anaphylatoxins
products of complement activation which have potent effects of smooth muscle contraction and vascular permeability
bacterial opsonization
the process by which a specific molecule binds to the surface of a bacterium
cellular recruitment
the second phase of the acute inflammatory response; involves the accumulation of leukocytes at sites of tissue injury
chemotaxis
movement of cells in response to chemicals
cytokine
a group of low molecular weight chemotactic (involved in the movement of cells) proteins secreted by cells at sites of inflammation

small secreted proteins which mediate and regulate immunity, inflammation, and hematopoiesis
phagocytosis
the process of recognizing, internalizing, and digesting foreign material or the debris of injured cells
lysosomal enzymes
enzymes involved in the intracellular degredation of phagocytosed material
neutropenia
an abnormally small presence of circulating polymorphonuclear leukocytes in the peripheral blood
macrophage
a pivotal cell in regulating the reactions that lead to chronic inflammation; a source of both inflammatory and immunologic mediators

destroy bacteria, protozoa, and tumor cells. They also release substances that stimulate other cells of the immune system. And they are involved in antigen presentation.
plasma cells
lymphoid cells that are the primary source of antibodies
lymphocytes
involved in both humoral and cell-mediated immune responses
eosinophils
cells often involved in allergic reactions and parasitic infestations
epithelioid cells
macrophages that have undergone characteristic changes in response to chronic inflammation
leukocytosis
an increase in the numbers of circulating leukocytes commonly accompanying acute inflammation