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28 Cards in this Set
- Front
- Back
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inflammation
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a reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues
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edema
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an increase in extravascular fluid
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effusion
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excess fluid in the cavities of the body
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transudate
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edema fluid with a loss of protein content
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exudate
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edema fluid with a high protein content
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serous
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effusion/exudate with absence of cellular response components
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serosanguinous
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effusion/exudate with erythrocytes
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fibrinous
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exudate with large amounts of fibrin from activation of the coagulation system
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purulent
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effusion/exudate with prominent cellular components
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suppurative
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purulent exudate is accompanied by significant liquefactive necrosis
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vasoactive mediators
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cellular components that influence responses of the microvasculature to injury
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platelet
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a peripheral blood component arising from bone marrow that plays a primary role in the initiation and regulation of clot formation
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mast cell
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cell within connective tissue containing receptors for IgE; when stimulated by an antigen, a variety of inflammatory mediators are secreted into extracellular tissues
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complement system
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group of 20 plasma proteins that are a source of vasoactive mediators and play an important role in host defense against bacterial infection
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anaphylatoxins
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products of complement activation which have potent effects of smooth muscle contraction and vascular permeability
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bacterial opsonization
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the process by which a specific molecule binds to the surface of a bacterium
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cellular recruitment
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the second phase of the acute inflammatory response; involves the accumulation of leukocytes at sites of tissue injury
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chemotaxis
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movement of cells in response to chemicals
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cytokine
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a group of low molecular weight chemotactic (involved in the movement of cells) proteins secreted by cells at sites of inflammation
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phagocytosis
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the process of recognizing, internalizing, and digesting foreign material or the debris of injured cells
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lysosomal enzymes
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enzymes involved in the intracellular degredation of phagocytosed material
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neutropenia
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an abnormally small presence of circulating polymorphonuclear leukocytes in the peripheral blood
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macrophage
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a pivotal cell in regulating the reactions that lead to chronic inflammation; a source of both inflammatory and immunologic mediators
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plasma cells
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lymphoid cells that are the primary source of antibodies
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lymphocytes
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involved in both humoral and cell-mediated immune responses
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eosinophils
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cells often involved in allergic reactions and parasitic infestations
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epithelioid cells
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macrophages that have undergone characteristic changes in response to chronic inflammation
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leukocytosis
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an increase in the numbers of circulating leukocytes commonly accompanying acute inflammation
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