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This is most common type of necrosis seen under the
microscope. The nucleus initially becomes small and darkly basophilic (pyknosis) followed by disintegration (karyorrhexis) and eventual loss of staining (karyolysis). The cytoplasm is densely eosinophilic. |
Coagulative necrosis
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EX: acute myocardial infarction
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Essentially an abcess where the infiltration of neutrophils precludes (prevents) complete coagulative necrosis.
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2. Liquefactive necrosis:
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EX: wet gangrene of soft tissues as in diabetes
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Classically associated with tuberculosis and other necrotizing granulomatous disorders.
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Caseous necrosis
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EX: pulmonary tuberculosis
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Used to refer to necrosis of vascular walls in which the insudation of plasma proteins which stain intensely eosinophilic.
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Fibrinoid necrosis:
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EX: temporal (giant cell) arteritis
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