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22 Cards in this Set
- Front
- Back
Lichen Planus
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4 P's: Purple, Pruritic Polygon Papules
Type IV disorder Sawtooth Rete Pegs Reticular Form: more common, asymp, Wickham's Striae, waxing and waning Erosive: pain/ulcer, desquam gingivitis Tx: corticos |
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Lichenoid Mucositis/Dermatitis
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Looks like Lichen Planus, but see perivaculitis! (lymphocytes around bv)
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What are some other causes for LP-like lesions?
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Ibuprofen/meds
Lupus Graft vs Host disease Cinnamon Dental materials Chronic Ulcerative Stomatitis |
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Benign Mucous Membrane Pemphigoid (Cicatricial pemphigoid)
"BMMP" |
Autoimmune
Vesiculobullous No skin lesions Scarring, Opthamologist consult Hemi-des and B-M atttacked (sub-epithelial cleave) ONLY DIF |
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Bullous Pemphigoid
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Autoimmune
Skin lesions present, oral uncommon No scarring Sub-epithelial split Both DIF and IIF |
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Pemphigus Vulgaris
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Auto-IgG's against DESMOGLEIN-3
Vessiculo-bullous Acantholysis (cell sep) suprabasilar cleavage Mild trauma = damage (bra..etc) Tzanck cells Tombstones & Chicken wire |
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Lupus Erythematosus: basic info
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Auto-ab's against nuclear stuff & Smith Antigen
Immune complex damage (Type III) DIF - detects B-M ab's |
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Systemic Lupus Eythematosus
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Butterfly rash, w/ photosensitivity
Oral lesions are vague and not diagnostic |
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Chronic Cutaneous Lupus Eythematosus (Discoid Lupus)
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Skin lesions in sun-exposed areas
Plaques that heal with scarring Intraorals look like LP erosive |
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Recurrent Aphtous Stomatitis basics
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Canker sores
Damage = T-cell mediated (CD8), with minimal CD4's |
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Minor Aphtous Stomatitis
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NON-KERA, moveable mucosa
Yellow-gray ulcer with eryth halo 3-10mm Heal without scarring 7-10 days |
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Major Aphtous Stomatitis
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>1cm
SCARS Deeper than minor Topical corticos and benzo Magic mouthwash... |
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Herpetiform Aphthous Ulcerations
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Rare, tons of little ulcers
BOTH kera and non-kera Many at one time Looks similar to herpes sores |
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Behcets Disease / Syndrome
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Chronic inflammatory dz
99.9% will have an oral component Focus on ocular / mucous / arthritic / neurologic Dx = 3x in one year, + ocular / skin lesion / +pathergy test (need 2 of 3) |
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Primary (aka Acute) Herpetic Gingivostomatitis
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Usually asymptomatic
Lots exposed in ado/college Symptomatics: constitutional signs..fever..lymphadeno KERA AND NONKERA Acantholysis / Tzanck cells Tx: just palliative |
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Where does HSV 1 lie latent?
HSV2? What does adult-onset HSV1 usually entail? |
HSV1: Trigeminal ganglion
HSV2: Sacral nerve root Onset = pharyngitis / tosilitis |
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Secondary (Recurrent) Herpes
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trauma/stress/mentrual/UV/pregnancy/systemic illness
Most common: herpes labialis vermilion border "Prodromals" precede (itchy/burn) IO: KERA ONLY One side, not diffuse Tx: Acyclovir, but only during prodromal |
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Herpes Zoster (shingles)
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Chpox trig from dental/immunosupp/alc
Rarely more than 1 occurrence Vesicles rupture, follow d-tome KERA and NONKERA SCARRING (V1------>ocular) |
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Erythema Multiforme Minor
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More common than major
Skin and mucosa, TARGET lesions (pathognomonic) Lips - bloody blisters w/ crust Tx is unclear |
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Erythema Multiforme Major (Stephen Johnson syndrome)
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Get OCULAR and genital in addition to the skin lesions in EM minor.
Scarring... Drug trigger |
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Toxic Epidermal Necrolysis (Lyell's Disease)
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Deadly form of EM
Drug trigger Diffuse skin sloughing |
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Desquamative Gingivitis
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NON-SPECIFIC TERM, just means loss of gingival epithel
Painful Might be: Erosive LP or Lichenoid Muc, Cicatricial pemphigoid, Pemphigus Vulgaris.. |