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11 Cards in this Set
- Front
- Back
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Describe the structure of Helicobacter pylori
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Small, curved, gram negative rods. non spore forming, motile by polar flagella, microaeophilic and capnophilic, grow at temperatures between 30 and 37 degrees celcius.
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Where does Helicobactor pylori grow?
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In the stomach epithelial cells.
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How can the helicobacter pylori survive in the stomach?
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produces urease which neutralizes stomach acid.
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What happens to the stomach while Helicobacter pylori survives in it?
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Inflammation and damage to the cells lining the stomach.
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How does transmission occur, and long does it last?
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Fecal-oral, and is usually life-long.
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How many people are colonized with Helicobacter pylori?
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half the world's population - most people in underdeveloped countries and fewer people in developed countries.
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What are some clinical diseases caused bye Helicobacter pylori?
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Gastritis, Gastric and duodenal ulcers, chronic ulcers can lead to carcinomas.
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What are the two types of gastric carcinomas?
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Gastric adenocarcinoma and gastric MALT lymphomas
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What is a gastric adenocarcinoma?
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A tumor that begins as glandular tissue.
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What is a gastric MALT lymphoma?
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mucosa associated lymphoid tissue.
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How can you treat Helicobacter pylori?
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Treatment with a single antimicrobial agent is ineffective, often 3-4 are used. Some antimicrobials are ineffective in the acidity of the stomach.
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