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59 Cards in this Set

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which type of hypersensitivity Rxn is IgE mediated?
Type I: ie anaphylactic
which type of hypersensitivity Rxn is antibody(IgG,IgM) mediated?
Type II
which type of hypersensitivity Rxn is cytotoxic, IgG, IgM, or complement mediated?
Type III
which type of hypersensitivity Rxn is a delay reaction T-cell mediated?
Type IV: PPD test
name a gram + bacteria that appears in chains
Streptococcus
name a gram + bacteria that appears in clusters
Staphylococcus
Which organism produces membraneous colitis and is usually assoc. with antibiotics?
C.Diff; Gram + organism found in the GI tract
which drugs are used to treat TB?
RIPE

Rifampin
INH
PZA
Ethambutol
What is Legionnaire's disease?
Caused by Gram negative bacteria Legionella; causes pneumonia
Name the CONDM drugs
Clotcicillin
Oxycillin
Nothcillin
Diclotcicillin
Methecillin
Name some Macrolides
clarithromycin
roxithromycin
erythromycin
azithromycin
dirithromycin
name a quinolone and it's target site
Ciprofloxacin; affects DNA synthesis
What is Toxoplasmosis
Protozoal disease that effects a fetus whose mother first contracts the disease during pregnancy through contact with an infected human or cat
This disease is caused by protozoan parasites of the genus Plasmodium
Malaria
name 2 protozoa
Trichomonas
Malaria
What is Toxoplasmosis
Protozoal disease that effects a fetus whose mother first contracts the disease during pregnancy through contact with an infected human or cat
which organism causes Lyme disease?
Borrelia
Which of these is NOT a Fungus?

Candida
Histoplasmosis
Aspergillus
Cryptococcus
Listeria
Listeria; this is a Gram + bacteria
what is the difference between the herpes ulcer and the syphlis ulcer?
Syphllis ulcer is painless
mycoplasma, legionella, and clamydiae usually cause?
Pneumonias (atypical)- stain does not show organism
This disease usually affects the lungs and is causes by a fungus found in poultry house litter, caves, areas harboring bats, and in bird roosts
Histoplasmosis
Which drugs are used to Tx fungal infections?
Amphotericin
Fluconazole
Intraconazole
name some examples of amino glycosides
NGTS

Neomycin
Gentomycin
Tobromycin
Streptomycin
Amikacin
What is the Ghon's complex?
progression of TB infection:

Formation of caseous (cheeselike) necrosis and lymph node granulomas
how do you treat MRSA?
Vancomycin which is a glycopeptide
Which drugs have hearing and kidney impairment as side effects?
aminoglycosides
which drugs have liver or bone marrow toxicity as side effects?
Chloramphenicol
Fluoroquinolones
what drugs is used to treat CMV infections?
Ganciclovir (antiviral)
this is a small molecule which can elicit an immune response only when attached to a protein
Hapten
what are the common organisms assoc. with otitis media?
H. flu
Streptococcus
M.catarallis
Auer Rods
AML
Philly Chromosome
CML
Bone lesions
Multiple myeloma
immunoglobulin assoc. with early immune response; ABO blood antigen
IgM
which organism causes syphlis?
Treponema Pallidum; gram - bacteria
drug assoc. with ototoxic and renal complications
Gentamycin
drug assoc. with pseudomembraneous colitis
clindamycin
this drug works by inhibiting the action of ribosomes
tetracyclin
These antibiotics work by inhibiting the bacterial cell wall synthesis
beta-lactam antibiotics
cephalosporin
etc
this drug treats a variety of bacterial infections and works by inhibiting successive steps in the folate synthesis pathway
Bactrim
what does activation complement lead to?
cytolysis
chemotaxis
opsonization
immune clearance
inflammation
marking of pathogens for phagocytosis
what is opsonization?
coating to act as a binding enhancer for the process of phagocytosis
what is the Membrane Attack Complex?
formed as a result of complement, it acts, analogically, like an oil rig by drilling into the cell and having the contents come out.
name 1st Gen. Cephalosporin
Velosf
Keflex
Duricef
2nd Gen. Cephalosporin to treat H.flu
Ceftin
this is an antibiotic with an increased spectrum of action against β-lactamase producing amoxicillin-resistant bacteria.
Augmentin: Amoxicillin + Clavulanic acid
what is Ampicillin/sulbactam (Unasyn) used to for?
treatment of infections caused by bacteria resistant to beta-lactam antibiotics
First-generation cephalosporins are predominantly active against?
Gram-positive bacteria
Gram negative
2nd Gen. Cephalosporins are active against what type of bacteria?
Gram negative
3rd Gen Cephalosporins treat?
Gram nagative

little activity for gram +
what are the 1st Gen Cephalosporins?
Cefazolin
Cefadroxil
Cephadine (Velosef)
Cephalothin
Cefalexin (Keflex)
a small molecule which can elicit an immune response only when attached to a large carrier such as a protein
A hapten
Organisms assoc. with otitis media
H.flu
Strep pneumonia
M.catarallis
how do quinolones work?
By inhibiting DNA synthesis
an infusion reaction from fast administration of Vancomycin
Red man syndrome or red neck syndrome

flushing and rash that affects the face, neck and upper torso
a nephrotoxic and ototoxic drug
vancomycin
Vaccine against TB
BCG
Which drugs target the cell wall
PCN
Cephalosporins
Monobactams
Carbapenem
Which drugs target ribosomes(protein synthesis)
Aminoglycosides
Tetracyclines
Macrolides

Glycopeptides
Oxazolidinone
Rifampin
Streptogramin