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59 Cards in this Set
- Front
- Back
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which type of hypersensitivity Rxn is IgE mediated?
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Type I: ie anaphylactic
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which type of hypersensitivity Rxn is antibody(IgG,IgM) mediated?
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Type II
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which type of hypersensitivity Rxn is cytotoxic, IgG, IgM, or complement mediated?
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Type III
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which type of hypersensitivity Rxn is a delay reaction T-cell mediated?
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Type IV: PPD test
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name a gram + bacteria that appears in chains
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Streptococcus
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name a gram + bacteria that appears in clusters
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Staphylococcus
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Which organism produces membraneous colitis and is usually assoc. with antibiotics?
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C.Diff; Gram + organism found in the GI tract
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which drugs are used to treat TB?
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RIPE
Rifampin INH PZA Ethambutol |
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What is Legionnaire's disease?
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Caused by Gram negative bacteria Legionella; causes pneumonia
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Name the CONDM drugs
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Clotcicillin
Oxycillin Nothcillin Diclotcicillin Methecillin |
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Name some Macrolides
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clarithromycin
roxithromycin erythromycin azithromycin dirithromycin |
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name a quinolone and it's target site
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Ciprofloxacin; affects DNA synthesis
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What is Toxoplasmosis
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Protozoal disease that effects a fetus whose mother first contracts the disease during pregnancy through contact with an infected human or cat
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This disease is caused by protozoan parasites of the genus Plasmodium
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Malaria
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name 2 protozoa
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Trichomonas
Malaria |
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What is Toxoplasmosis
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Protozoal disease that effects a fetus whose mother first contracts the disease during pregnancy through contact with an infected human or cat
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which organism causes Lyme disease?
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Borrelia
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Which of these is NOT a Fungus?
Candida Histoplasmosis Aspergillus Cryptococcus Listeria |
Listeria; this is a Gram + bacteria
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what is the difference between the herpes ulcer and the syphlis ulcer?
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Syphllis ulcer is painless
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mycoplasma, legionella, and clamydiae usually cause?
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Pneumonias (atypical)- stain does not show organism
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This disease usually affects the lungs and is causes by a fungus found in poultry house litter, caves, areas harboring bats, and in bird roosts
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Histoplasmosis
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Which drugs are used to Tx fungal infections?
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Amphotericin
Fluconazole Intraconazole |
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name some examples of amino glycosides
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NGTS
Neomycin Gentomycin Tobromycin Streptomycin Amikacin |
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What is the Ghon's complex?
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progression of TB infection:
Formation of caseous (cheeselike) necrosis and lymph node granulomas |
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how do you treat MRSA?
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Vancomycin which is a glycopeptide
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Which drugs have hearing and kidney impairment as side effects?
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aminoglycosides
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which drugs have liver or bone marrow toxicity as side effects?
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Chloramphenicol
Fluoroquinolones |
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what drugs is used to treat CMV infections?
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Ganciclovir (antiviral)
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this is a small molecule which can elicit an immune response only when attached to a protein
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Hapten
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what are the common organisms assoc. with otitis media?
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H. flu
Streptococcus M.catarallis |
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Auer Rods
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AML
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Philly Chromosome
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CML
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Bone lesions
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Multiple myeloma
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immunoglobulin assoc. with early immune response; ABO blood antigen
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IgM
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which organism causes syphlis?
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Treponema Pallidum; gram - bacteria
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drug assoc. with ototoxic and renal complications
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Gentamycin
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drug assoc. with pseudomembraneous colitis
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clindamycin
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this drug works by inhibiting the action of ribosomes
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tetracyclin
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These antibiotics work by inhibiting the bacterial cell wall synthesis
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beta-lactam antibiotics
cephalosporin etc |
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this drug treats a variety of bacterial infections and works by inhibiting successive steps in the folate synthesis pathway
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Bactrim
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what does activation complement lead to?
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cytolysis
chemotaxis opsonization immune clearance inflammation marking of pathogens for phagocytosis |
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what is opsonization?
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coating to act as a binding enhancer for the process of phagocytosis
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what is the Membrane Attack Complex?
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formed as a result of complement, it acts, analogically, like an oil rig by drilling into the cell and having the contents come out.
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name 1st Gen. Cephalosporin
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Velosf
Keflex Duricef |
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2nd Gen. Cephalosporin to treat H.flu
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Ceftin
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this is an antibiotic with an increased spectrum of action against β-lactamase producing amoxicillin-resistant bacteria.
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Augmentin: Amoxicillin + Clavulanic acid
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what is Ampicillin/sulbactam (Unasyn) used to for?
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treatment of infections caused by bacteria resistant to beta-lactam antibiotics
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First-generation cephalosporins are predominantly active against?
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Gram-positive bacteria
Gram negative |
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2nd Gen. Cephalosporins are active against what type of bacteria?
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Gram negative
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3rd Gen Cephalosporins treat?
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Gram nagative
little activity for gram + |
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what are the 1st Gen Cephalosporins?
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Cefazolin
Cefadroxil Cephadine (Velosef) Cephalothin Cefalexin (Keflex) |
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a small molecule which can elicit an immune response only when attached to a large carrier such as a protein
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A hapten
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Organisms assoc. with otitis media
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H.flu
Strep pneumonia M.catarallis |
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how do quinolones work?
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By inhibiting DNA synthesis
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an infusion reaction from fast administration of Vancomycin
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Red man syndrome or red neck syndrome
flushing and rash that affects the face, neck and upper torso |
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a nephrotoxic and ototoxic drug
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vancomycin
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Vaccine against TB
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BCG
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Which drugs target the cell wall
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PCN
Cephalosporins Monobactams Carbapenem |
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Which drugs target ribosomes(protein synthesis)
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Aminoglycosides
Tetracyclines Macrolides Glycopeptides Oxazolidinone Rifampin Streptogramin |
