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19 Cards in this Set

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Thyroid Hormones


Thyroid gland secretes thyroid hormones:






› Thyroxine (T4)
› Triiodothyronine (T3)

Thyroid hormones




Follicular cells of the thyroid gland produce and


secrete what type of hormone?



thyroid hormones

Thyroid hormones




Approximately 90% of the thyroid hormone is in the form of ________, whereas 10% is _______

T4



T3

Thyroid hormones



Released T4 and T3 are lipid soluble and diffuse from what?

the follicle into circulation

Steroid Hormones



Adrenal medulla secretes ______________ and ____________ in response to sympathetic nervous system stimulation

epinephrine and norepinephrine

Steroid Hormones





Hormones produced by the adrenal cortex are


called steroids and include:

› Glucocorticoids (cortisol)
› Mineralocorticoids (aldosterone)


› Sex steroids (androgens)

Steroid Hormones




The outer zona glomerulosa produces the


mineralocorticoid aldosterone in response to


stimulation by what?

A II

Steroid Hormones



The middle zona fasciculata produces the


glucocorticoid, cortisol, in response to whAT?

ACTH

Steroid Hormones



The inner zona reticularis is adjacent to the adrenal medulla and produces what?

androgen, DHEA

Steroid Hormones



Made on demand and not stored in _____



cells.

Steroid Action on Target Cells

1. Travel in circulation bound to proteins



2. Diffuse through their target cell membranes and bind with their respective cytoplasmic receptors



3. Hormone-receptor complex rapidly translocates into the nucleus


Steroid Action on Target Cells


Glucocorticoids

› Primary effect on glucose metabolism

Steroid Action on Target Cells


Mineralocorticoids (aldosterone)



Maintain normal salt and water balance by promoting what?

sodium retention and potassium excretion at the distal renal tubules

Steroid Action on Target Cells


Mineralocorticoids (aldosterone)



Aldosterone secretion is regulated primarily by what?

renin-angiotensin system associated with the juxtaglomerular cells of the kidney

Hyposecretion



Primary hyposecretion occurs when an endocrine gland releases an __________ amount of hormone to meet physiologic needs

inadequate

Hyposecretion



Secondary hyposecretion occurs when secretion of a ________ _____________ is inadequate to cause the target gland to secrete adequate amounts of hormone

tropic hormone

Hypersecretion




› Primary hypersecretion occurs when there is a dysfunction of the __________ _________ that results in abnormally high secretion of hormone

endocrine gland

Hypersecretion



Secondary hypersecretion occurs when there is an elevation in the _______ __________ of one hormone that results in an increased plasma concentration of another hormone

tropin levels

Target cell hyporesponsiveness

Typically due to lack of or a deficiency in cellular receptors