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80 Cards in this Set

  • Front
  • Back
Dehydration
Fluid volume overload
Fluid compartments
Extracellular fluid
Intracellular fluid
Transcellular fluid,in epithelial cells, saliva, CSF
Infants H20
70 to 80%
Adults H20
60%
Elderly Adults
45 to 55% H2o
who has more water men or women
Men due to less fat content
The primary body fluid
lubricates
transports
solvent for electrolytes
Electrolytes
water balance
acid base balance
enzyme reaction
very important with neuromuscular activity
where do we get our water
ingested 2000
and it is oxidized in food
Water loss
skin 300 to 500
lung 400 to 500
urine 1000 to 5000
stool 100 ml
what are you looking for in urine
specific gravity which is urine concentration, this has a direct reflection on electrolytes
Diarrhea
an adult can have loose stools for 3 or 4 days but watch out for kids and elderly
dehydration can happen very fast
Meds what kinds of interaction will these cause
meds can throw off electrolytes, you will need to replace them example lasix
abnormal fluid losses
Fever
Burns
Hemorrhage
Emesis
Secretions
Wound Exudate
Diaphoresis
Heart Problems
Why do we lose so much water due to burns
because of the albumin leakage. water will follow it and the patient will lose a large amount of fluid, they can also 3rd space water keep an eye on them.
Purpose of IV solution
Maintenance
catch up
keep up
nutrition
adminstration
Emises
they lose potasium and become acidotic.
They lose fluids
Dont forget aspiration
Osmotic presure
the power of a solution to draw water across a membrane
Tonicity
Effect a solutions osmotic pressure has on water movement across a cell membrane within that solution
Isotonic solution
has the same solutes as plasma.
hypertonic solution
greater cconcentrations of solutes than plasma
Organs that maintain fluid and electrolyte balance
Kidney
Cardiovascular system
Lungs
Adrenal Glands
Pituitary Gland
Parathyroid
Thyroid
Hypothalamus
Intestine
What do the kidneys do
regulates I and O
Filters blood
Cardiovascular system
pumps and perfuses the kidney
problems here will cause all kinds of fluid build up
Lungs
asses for fluid build up
this is a source of water loss and can excrete co2 and change Ph balance
Adrenal glands
secretes aldosterone which will retain Na, and water and secrete K
Pituitary
stores ADH which retains water only
Parathyroid
PTH -CA
Thyroid
hormones increase-blood flow increases, and kidney perfusion
Hypothalamus
thirst center
Intestine
dehydration will cause the intenstines to take more water out of the stool, which can cause major impaction
insulin
allows potasium to enter the cell along with suger this causes the Na to go out and Hydrogen to go out ....and throws off the hydrogen ions
Plasma Protein
albumin, keeps fluid in our vessels
Glucose
important to keep vascular space normal sugar and water needs to be equal
How do the kidneys save water
Na is retained thus water is retained
Dehydration can cause
H/A
Fever can cause
Dehydration
Vasodilation
Vomiting
electrolyte imbalance
dehydration causes (isotonic)
Inadequate fluid intake
excessive fluid loss
third spacing
potasium
shaky people the potasium fires the neruons
Hypertonic Dehydration
2nd most common dehydration
loss of extracellular fluid
-increase in plasma osmotic pressure
-fluid is pulled from the Intracellular fluid
-cell dehydration
-ADH is released increasing H20 reabsorption
-the hypothalamus thirst center is activated to get you to drink more
norms for Na
Ca
K
What are they going to do to you if they swing to high or to low
answer this using patho book
remember nervous system
calciam is important
because the bones use it so keep your patient moving, and if you have too much ca you can get kidney scaring and stones
assesment priority
ABC
Discuss the functions of the regulatory mechanisms that maintain water and electrolyte balance in the body
Renal regulation adjusts the water balance and electrolyte balance This adjustment helps maintain normal plasma osmolality, electrolyte balance , blood volume and acid base balance
Describe cardiac regulation of fluids
ANP and BNP are hormones producd by cardiomyocytes. They are antagonists to the Renin angiotensin aldosterone system. When they sense increased arterial pressure or high serum sodium they suppress secretion of aldosterone, renin , and ADH
What is insensible water loss
it is invisible vaporization from the lungs and skin, assist in regulating body temp. about 600 to 900ml lost dailey
Describe a drenal corticla regulation of water
The hypothalamus tells the posterior pituitary gland to release ADH and the kidney holds on to water
It also tells the anterior pituitary to release ACTH which effects the adrenal cortex, this causes the release of aldosterone and cortisol causing the retention of Na and K+ excretion.
what is venous hydrostatic pressure
it is about 10 mmhg and elevation can be caused by fluid overload, heart failure,liver failure, thrombosis, varicose veins
Decreased plasma oncotic pressure
this can cause fluid to remain in the interstitium,
caused by excesive protien loss from kidney failure, malnutirition or failure of the liver to do protien synthesis
Elevation of interstitial oncotic pressure
this can cause albumin to leak out into the interstitium and cause a huge water loss
Normal electrolyte values for potassium K+ is
3.5 to 5.0 mEq/L
Normal electrolyte values for Magnesium Mg2+ is
1.5 to 2.5 mEq/L
Normal electrolyte values for Sodium Na+ is
135 to 145 mEq/L
Normal electrolyte values for Calcium Ca2+ is
4.5 to 5.5 mEq/L
Normal values for Bicarbonate HCO3- is
22-26 mEq/L
Normal values for Chloride cl- is
96 to 106 mEq/L
Normal values for Phosphate is PO43-
2.8 -4.5 mg/dl
What are some ways edema is managed
Medications such as colloids, dextran, mannitol, or hypertonic solutions. this will draw the fluid out of the interstitium
Increasing hydrostatic pressure is another way such and wearing elastic compression socks
what are the normal values for Na
135 to 145 mEq/L
what are the nomal values for potassium
3.5 to 5 mEq/L
What are the normal values for Calcium
4.5 to 5.5 mEq/L
What are the normal values for Magnesium
1.5 to 2.5 mEq/L
What are the normal values for Phosphate
1.7 to 4.6 mg/100ml
Symptoms of Hypernatremia
lethargy, weakness, irritability, and edema. With more severe elevations of the sodium level, seizures and coma may occur.

Severe symptoms are usually due to acute elevation of the plasma sodium concentration to above 158 mEq/L (normal is typically about 135-145 mEq/L). Values above 180 mEq/L are associated with a high mortality rate, particularly in adults. However such high levels of sodium rarely occur without severe coexisting medical conditions.
Symptoms of Hyponatremia
Severe hyponatremia may cause osmotic shift of water from the plasma into the brain cells. Typical symptoms include nausea, vomiting, headache and malaise. As the hyponatremia worsens, confusion, diminished reflexes, convulsions, stupor or coma may occur. Since nausea is, itself, a stimulus for the release of ADH, which promotes the retention of water, a positive feedback loop may be created and the potential for a vicious circle of hyponatremia and its symptoms exists
Symptoms of Hyperkalemia
malaise, palpitations and muscle weakness; mild breathlessness may indicate metabolic acidosis, one of the settings in which hyperkalemia may occur
what causes hypocalcemia
hypoparathyroidism
what are the symptoms of hypocalcemia
Perioral tingling and parasthesia, 'pins and needles' sensation over the extremities of hands and feet. This is the earliest symptom of hypocalcemia.
Tetany, carpopedal spasm are seen.
what are the symptoms of hypercalcemia
Hypercalcemia per se can result in fatigue, depression, confusion, anorexia, nausea, vomiting, constipation, pancreatitis or increased urination
what causes hypercalcemia
hyperthyroidism
what are the symptoms of Hypomagnesemia
hypokalemia
Deficiency of magnesium causes weakness, muscle cramps, cardiac arrhythmia, increased irritability of the nervous system with tremors, athetosis, jerking, nystagmus and an extensor plantar reflex. In addition, there may be confusion, disorientation, hallucinations, depression, epileptic fits, hypertension, tachycardia and tetany.
What are the symptoms of Hypermagnesemia
Weakness, nausea and vomiting
Hypotension
Impaired breathing
Arrhythmia and asystole, most prominent cardiac symptoms are due to conduction delays, since magnesium acts as physiologic calcium blocker
what are the symptoms of Hypophosphatemia
Muscle dysfunction and weakness. This occurs in major muscles, but also may manifest as diplopia, low cardiac output, dysphagia, and respiratory depression due to respiratory muscle weakness.
Mental status changes. This may range from irritability to gross confusion, delirium, and coma.
White cell dysfunction, causing worsening of infections
Instability of cell membrates due to low ATP levels: this may cause rhabdomyolysis
what causes Hypophosphatemia
Respiratory alkalosis Any alkalemic condition moves phosphate out of the blood into cells. This includes most common respiratory alkalemia
Increased excretion (e.g. in hyperparathyroidism)
Describe Hyperphosphatemia
Often, calcium levels are lowered (hypocalcemia) due to precipitation of phosphate with the calcium in tissues.
It can be caused by hypoparathyroidism and is commonly seen in chronic renal failure. High phosphate levels can be avoided with phosphate binders and dietary restriction of phosphate.

Signs and symptoms include ectopic calcification, secondary hyperparathyroidism, and renal osteodystrophy.
What can lower calcium levels
Hyperphosphatemia
what will blood gasses show in Acidosis
Arterial blood gasses will indicate low pH, low blood HCO3, and normal or low PaCO2.
how can you tell the difference between respiratory or metabolic acidosis
in respiratory acidosis, the CO2 is increased while the bicarbonate is either normal (uncompensated) or increased (compensated). Compensation occurs if respiratory acidosis is present, and a chronic phase is entered with partial buffering of the acidosis through renal bicarbonate retention.
What are the symptoms of Acidosis
Symptoms may include chest pain, palpitations, headache, altered mental status, decreased visual acuity, nausea, vomiting, abdominal pain, altered appetite (either loss of or increased) and weight loss (longer term), muscle weakness and bone pains. Those in metabolic acidosis may exhibit deep, rapid breathing
How does insulin effect Potasium
forces cells to absorb serum potassium; lack of insulin inhibits absorption.