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13 Cards in this Set
- Front
- Back
Defects in humoral immunity (B cell), increases the risk of these types of infections
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Pyogenic:
Strep pneumoniae H.flu Staph aureus Pseudomonas |
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Release of mast cell mediators triggers this type of hypersensitivity reaction
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Type I: IgE antibody
Immediate hypersensitivity |
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complement-mediated opsonization and phagocytosis triggers this type of hypersensitivity reaction
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Type II: antibody mediated
Humoral antibodies participate in injuring cells by predisposing them to lysis or phagocytosis |
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what is the immune mechanism of Type II hypersensitivity reaction
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IgM, IgG antibodies against cell surface or extracellular matrix
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Formation of immune complexes is characteristic of this type of hypersensitivity
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Type III: Humoral antibodies bind antigen and activate complement
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What is type IV hypersensitivity?
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T-cell mediated: Cytokine mediated inflammation
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what causes B-cells to produce IgE?
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stimulation by an antigen-stimulated T-H2 cell
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Name examples of Type I reactions
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Anaphylactic
Atopic (urticaria,allergic rhinitis, atopic dermatitis, food allergies, asthma) |
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Which foods are most reponsible for anaphylactic reactions?
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peanuts
tree nuts shellfish |
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Blood transfusion reactions and hemolytic disease of the newborn are examples of this type of hypersensitivity reaction
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Type II
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vasculitis in SLE and glomerulonephritis are caused by this type of reaction
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Type III
Also responsible for: Serum sickness The Arthus reaction(localized tissue necrosis) |
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Give examples of a delayed-type hypersensitivity Type IV reaction
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TB test
Contact dermatitis(cosmetics, hair dyes, metals, topical drugs) |
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Type of reaction caused by latex gloves
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Can either be type I or type IV
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