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13 Cards in this Set

  • Front
  • Back
Defects in humoral immunity (B cell), increases the risk of these types of infections

Strep pneumoniae
Staph aureus
Release of mast cell mediators triggers this type of hypersensitivity reaction
Type I: IgE antibody

Immediate hypersensitivity
complement-mediated opsonization and phagocytosis triggers this type of hypersensitivity reaction
Type II: antibody mediated

Humoral antibodies participate in injuring cells by predisposing them to lysis or phagocytosis
what is the immune mechanism of Type II hypersensitivity reaction
IgM, IgG antibodies against cell surface or extracellular matrix
Formation of immune complexes is characteristic of this type of hypersensitivity
Type III: Humoral antibodies bind antigen and activate complement
What is type IV hypersensitivity?
T-cell mediated: Cytokine mediated inflammation
what causes B-cells to produce IgE?
stimulation by an antigen-stimulated T-H2 cell
Name examples of Type I reactions
Atopic (urticaria,allergic rhinitis, atopic dermatitis, food allergies, asthma)
Which foods are most reponsible for anaphylactic reactions?
tree nuts
Blood transfusion reactions and hemolytic disease of the newborn are examples of this type of hypersensitivity reaction
Type II
vasculitis in SLE and glomerulonephritis are caused by this type of reaction
Type III

Also responsible for:
Serum sickness
The Arthus reaction(localized tissue necrosis)
Give examples of a delayed-type hypersensitivity Type IV reaction
TB test
Contact dermatitis(cosmetics, hair dyes, metals, topical drugs)
Type of reaction caused by latex gloves
Can either be type I or type IV