Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/17

Click to flip

17 Cards in this Set

  • Front
  • Back
Name the cardinal signs of inflammation
redness
swelling
heat
pain
loss of function
what are the 2 components of acute inflammation?
vascular stage
cellular stage
first WBC to arrive at inflammation site
Neutrophil
These cells increase in number during allergic reactions and parasitic infections
eosinophils
these cells contain histamine and produce symptoms assoc. with allergic rxns.
basophils
which chemical mediators are resposible for fever?
IL1
IL6
TNF
which chemical mediators are resposible for pain?
Bradykinin
Prostaglandins
which chemical mediators are resposible for swelling, redness, and tissue warmth?
Histamine
prostaglandins
leukotrienes
bradykinin
PAF
how does aspirin and NSAIDs work?
by inactivating an enzyme in the cyloocygenase pathway that produces prostaglandins
where does arachinodic acid come from?
Membrane phospholipids
which pathway forms leukotrienes
lipoxygenase
what is the most obvious sign of the acute phase response?
Fever
which cytokines are involved in the acute phase response?
IL1
IL6
TNF
which proteins are elevated during the acute phase response?
C-reactive protein
Fibrinogen

These reflect an accelerated ESR
what are the systemic effects of the acute phase response?
>ESR
fever
lethargy
> levels of CRP
Leukocytosis
in some cases, leukopenia
what is thromboxane?
a vasoconstrictor and a potent hypertensive agent, and it facilitates platelet aggregation
Most Common cause of nosocomial bacterial pneumonia
Streptococcus pneumoniae (pneumococcus)