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31 Cards in this Set

  • Front
  • Back

Most common malignancy of the vulva

squamous cell carcinoma

most common soft tissue sarcoma in childhood

Embryonal Rhabdomyosarcoma (ERMS)


- can be found in head/neck, upper/ lower extremities, retroperitoneum or GI tract.

What is a partial mole VS a complete mole?

Partial mole: 2 sperm fertilize one egg = 69 chromosomes




Complete mole: 2 sperm only = 46 paternal chromosomes

what is the best lab marker for determining menopause?

FSH levels (increased + LH increased)

What lab marker increases in polycystic ovarian syndrome (PCOS)?

Increased LH (more testosterone - get hairy)

what types pf HPV carry a high risk of malignancy?

HPV type 16 and 18.

What are the classifications of the Cervical Intraepithelial Neoplasm (CIN) types I-III?

CIN I - mild dysplasia of lower 1/3 of epithelium


CIN II - moderate dysplasia of lower 2/3 of epithelium


CIN III - severe dysplasia of FULL thickness of epithelium.

IntERlobular stroma VS. IntRAlobular stroma

Interlobular - separates one lobule from the other.


Intralobular - encloses each lobule.

Mastitis (Lactational mastitis)

fever and malaise that occurs in breastfeeding women. Localized and painful.

Which are non-invasive (in situ) carcinoma?

IntRAductal carcinoma and lobular carcinoma in situ.

Triple negative breast cancer

When there is absent expression of ER (estrogen receptor), PR (progesterone receptor) and HER2 (human epidermal growth receptor)


- very aggressive and most likely can only use chemo as tx.

Gynecomastia

hypertrophy of the male breast (when have increased estrogen, kleinfelter syndrome, chronic liver disease and testicular conditions in general).

Eisenmengar syndrome

when blood is being pumped from left to right and then reverses from right to left.

which is described as the artery of sudden death?

Left anterior descending artery obstruction.

stable VS. unstable angina

stable angina - pain upon physical activity


unstable angina - pain upon little or no physical activity.

STEMI vs. NSTEMI heart attack

STEMI - when the baseline on the ECG is elevated


NSTEMI - when the baseline on the ECG is decreased

In developed countries, rheumatic fever follows what bacteria?

Pharyngeal infection with rheumatogenic group A strep.


0.3-3% chance

Acute rheumatic fever (ARF) is developed after being exposed to what bacteria repeatedly?

Group A Strep

what accounts for the tissue injury that occurs in rheumatic fever?

Molecular mimicry

What are the symptoms of Acute Rheumatic Fever (ARF)?

Sore throat, symmetrical arthritis, Tenosynovitis (Disseminated gonococcal disease), syndehm chorea.



What is the major diagnostic criteria for ARF?

carditis, polyarthritis, chorea, erythema/ edema.


Make sure to confirm that there is fever, previous rheumatic fever, strep etc.

Which 'bodies' are very specific to rheumatic fever?

Aschoffs bodies (small giant cell granulomas)

What are the symptoms of Endocarditis?

Osler nodes - raised lesions on fingers


Roth spots - pale lesions in the retina surrounded by hemorrhage


Janeway lesion - lesions in the palm


Splinter hemorrhages in the nail beds.

What is the most characteristic cardiac manifestation of SLE?

Marantic endocarditis or Libman-Sacks endocarditis.




*NON-BACTERIAL endocarditis

What is the most common type of myocarditis?

Viral

Transudate VS. Exudate

Transudate - extracellular fluid as a result of increased fluid pressure or low oncotic pressure




Exudate - inflammatory fluid

What type of cancer possesses a propensity for cardiac metastasis?

Melanoma






*note: secondary cardiac tumors are 100X higher incidence than primary cardiac tumors.

Acute abdominal pain and diarrhoea and silent stomach sounds may indicate what - and is a serious condition?

Acute Peritonitis

What is Atresia?

Failure of embryological canalization of the proximal esophagus and the trachea.

Hiatus Hernia?

protrusion of the upper part of the stomach into the thorax

Mallory Weiss Syndrome VS. Boerhaave syndrome?

Mallory Weiss - rupture of the esophageal mucoda


Boerhaave - rupture of the whole thickness of the esophageal wall.